Results 91 to 100 of about 190,941 (272)
Advanced Intelligent Discovery, EarlyView.A physics‐guided machine learning framework estimates Young's modulus in multilayered multimaterial hyperelastic cylinders using contact mechanics. A semiempirical stiffness law is embedded into a custom neural network, ensuring physically consistent predictions. Validation against experimental and numerical data on C.
Christoforos Rekatsinas +4 more
wiley +1 more source
Imaging the Pharynx to Measure the Uptake of Doxorubicin in Caenorhabditis elegans
Bio-Protocol, 2017 Caenorhabditis elegans offers an array of advantages to investigate the roles of uptake transporters. Herein, an epifluorescent microscopy approach was developed to monitor the uptake of the autofluorescent anticancer drug, doxorubicin, into the pharynx ...
Sivathevy Amirthagunabalasingam +3 more
doaj +1 more source
Histone deacetylase HDA-1 modulates mitochondrial stress response and longevity
Nature Communications, 2020 Caenorhabditis elegans responds to mitochondrial stress by activating the mitochondrial unfolded protein response (UPRmt). Here the authors show that HDA-1, the C.
Li-Wa Shao +7 more
doaj +1 more source
CemOrange2 fusions facilitate multifluorophore subcellular imaging in C. elegans [PDF]
, 2019 Due to its ease of genetic manipulation and transparency, Caenorhabditis elegans (C. elegans) has become a preferred model system to study gene function by microscopy.
Buland, Justin R +14 more
core +3 more sources
CAENORHABDITIS ELEGANS AND ANGIOGENESIS
TURKISH MEDICAL STUDENT JOURNAL, 2019 Abstract: Angiogenesis is sprouting of new capillaries from already existing ones. It is a dynamic process that can be seen in every phase of human life. It is among the dynamic mechanisms of both physiological and pathological processes. Vascular endothelial growth factor is one of the many molecules that play a role in angiogenesis.
KILIÇÇALAN, İbrahim +2 more
openaire +3 more sources
Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases
Animal Models and Experimental Medicine, EarlyView.Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam +4 more
wiley +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
A practical guide to ordering C. elegans strains for biological research
Molecules and Cells: Caenorhabditis elegans (C. elegans) is a widely used model organism in biological research, contributing to our understanding of fundamental processes in areas such as development, neurobiology, and aging. Accessing the appropriate C.
Yeon-Ji Park +2 more
doaj +1 more source
Data on the effects of Glochidion zeylanicum leaf extracts in Caenorhabditis elegans
Data in Brief, 2019 The present article contains the data on the effects of Glochidion zeylanicum leaf extracts in C. elegans, which is related to the article '' Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in ...
Chatrawee Duangjan +5 more
doaj +1 more source
The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
Animal Research and One Health, EarlyView.A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source