Results 121 to 130 of about 279,189 (378)

Organogenesis of the Caenorhabditis elegans Intestine

Developmental Biology, 1999
The intestine of Caenorhabditis elegans is an epithelial tube consisting of only 20 cells and is derived clonally from a single embryonic blastomere called E. We describe the cellular events that shape the intestine. These events include cytoplasmic polarization of cells in the intestinal primordium, the intercalation of specific sets of cells, the ...
Ben Leung, James R Priess, Greg J. Hermann, Greg J. Hermann   +3 more
openaire   +3 more sources

The laboratory domestication of Caenorhabditis elegans [PDF]

Trends in Genetics, 2015
Model organisms are of great importance to our understanding of basic biology and to making advances in biomedical research. However, the influence of laboratory cultivation on these organisms is underappreciated, and especially how that environment can affect research outcomes.
Sterken, M.G., Snoek, L.B., Kammenga, J.E., Andersen, E.C.   +3 more
openaire   +3 more sources

Two New Cases Expand the Phenotypic Spectrum of TUBG1 Missense Variants

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The gamma‐tubulin ring complex (γ‐TuRC) plays a role in coordinating centrosome and spindle pole body formation during cell division. TUBG1 encodes a critical component of the γ‐TuRC. Pathogenic TUBG1 variants can cause a range of alterations in cortical gyral patterning, microcephaly, and other neurological manifestations.
Roser Urreizti, Jessica Vissicchio, Mohamed Idries, Monica Cozar, Raquel Rabionet, Tyhiesia Donald, Elizabeth J. Bhoj, Tomoki T. Nomakuchi, Shannon C. Shipley, Andrew E. Timms, Ghayda M. Mirzaa, Mercedes Serrano, Andrew K. Sobering   +12 more
wiley   +1 more source

Lifespan extension in Caenorhabditis elegans insulin/IGF-1 signalling mutants is supported by non-vertebrate physiological traits [PDF]

, 2017
The insulin/IGF-1 signalling (IIS) pathway connects nutrient levels to metabolism, growth and lifespan in eukaryotes ranging from yeasts to humans, including nematodes such as the genetic model organism Caenorhabditis elegans. The link between ageing and
Braeckman, Bart, Dhondt, Ineke
core   +2 more sources

Lipid and Carbohydrate Metabolism in Caenorhabditis elegans

Genetics, 2017
Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all aspects of organismal biology. Caenorhabditis elegans eat bacteria, which consist of lipids, carbohydrates, and proteins that are broken down during digestion into ...
J. Watts, M. Ristow
semanticscholar   +1 more source

The microRNAs ofCaenorhabditis elegans [PDF]

Genes & Development, 2003
MicroRNAs (miRNAs) are an abundant class of tiny RNAs thought to regulate the expression of protein-coding genes in plants and animals. In the present study, we describe a computational procedure to identify miRNA genes conserved in more than one genome.
Earl G. Weinstein, Nelson C. Lau, Lee P. Lim, Soraya Yekta, Aliaa Abdelhakim, David P. Bartel, Matthew W. Rhoades, Christopher B. Burge   +7 more
openaire   +3 more sources

Advanced Contactless Bioassembly Approaches: Leveraging Sound, Optical, and Magnetic Fields

Advanced NanoBiomed Research, EarlyView.
This review explores innovative contactless bioassembly techniques driven by sound, light, and magnetic fields, which enable the precise organization of cells, biomaterials, and bioactive substances into complex 3D structures. These technologies, crucial for in vitro modeling and regenerative medicine, are examined in detail, highlighting their ...
Micaela Natta, Greta Cocchi, Riccardo Tognato, Alessandro Cianciosi, Tiziano Serra   +4 more
wiley   +1 more source

Copper Oxide Nanoparticles Impact Several Toxicological Endpoints and Cause Neurodegeneration in \u3cem\u3eCaenorhabditis elegans\u3c/em\u3e [PDF]

, 2016
Engineered nanoparticles are becoming increasingly incorporated into technology and consumer products. In 2014, over 300 tons of copper oxide nanoparticles were manufactured in the United States.
Andersen, Erik C., Hristova, Krassimira R., Kappell, Anthony D., Mashock, Michael Joseph, Petrella, Lisa N., Zanon, Tyler   +5 more
core   +1 more source

The native microbiome of the nematode Caenorhabditis elegans: gateway to a new host-microbiome model

BMC Biology, 2016
Host-microbe associations underlie many key processes of host development, immunity, and life history. Yet, none of the current research on the central model species Caenorhabditis elegans considers the worm’s natural microbiome.
P. Dirksen, Sarah Arnaud Marsh, Ines Braker, N. Heitland, Sophia Wagner, Rania Nakad, Sebastian Mader, Carola Petersen, Vienna Kowallik, P. Rosenstiel, M. Félix, H. Schulenburg   +11 more
semanticscholar   +1 more source

Data set of differentially expressed microRNAs in sanguinarine-treated Caenorhabditis elegans and its F3 progeny

Data in Brief, 2018
This article presents small RNA sequencing data of Caenorhabditis elegans consist of P0 control worms (untreated), P0 worms treated with a plant alkaloid, sanguinarine, and its F3 offspring.
Yit-Lai Chow, Fumihiko Sato
doaj