Results 181 to 190 of about 193,403 (293)

Modulation of EGF receptor-mediated vulva development by the heterotrimeric G-protein G{alpha}q and excitable cells in C. elegans [PDF]

, 2003
Garcia, L. Rene, Iwasaki, Kouichi, Khan, Liakot A., Moghal, Nadeem, Sternberg, Paul W.   +4 more
core   +1 more source

Phosphorylation of an RNA‐Binding Protein Rck/Me31b by Hippo Is Essential for Adipose Tissue Aging

Aging Cell, EarlyView.
Evolutionary conserved Hippo/Mst1 signaling non‐canonically regulates the stability of mRNAs through directly phosphorylating a subset of RNA binding proteins to stabilize lipolytic mRNAs. Hpo pathway contributes to the regulation of Drosophila lifespan by modulating the expression and activity of Me31b/RCK, which subsequently affects mRNA levels of ...
Eunbyul Yeom, Hyejin Mun, Jinhwan Lim, Yoo Lim Chun, Kyung‐Won Min, Johana Lambert, L. Ashley Cowart, Jason S. Pierce, Besim Ogretmen, Jung‐Hyun Cho, Jeong Ho Chang, J. Ross Buchan, Jason Pitt, Matt Kaeberlein, Sung‐Ung Kang, Eun‐Soo Kwon, Seungbeom Ko, Kyoung‐Min Choi, Yong Sun Lee, Yoon‐Su Ha, Seung‐Jin Kim, Kwang‐Pyo Lee, Hyo‐Sung Kim, Seo Young Yang, Chang Hoon Shin, Je‐Hyun Yoon, Kyu‐Sun Lee   +26 more
wiley   +1 more source

HLH‐30/TFEB Rewires the Chaperone Network to Promote Proteostasis Upon Perturbations to the Coenzyme A and Iron–Sulfur Cluster Biosynthesis Pathways

Aging Cell, EarlyView.
Proteostasis enhancing treatments are potential therapies for many age‐related diseases. We discovered that interference with the CoA biosynthesis pathway and limiting iron‐sulfur cluster availability improve proteostasis in C. elegans. Proteostasis improvement under these conditions depends on the conserved HLH‐30/TFEB transcription factor, which ...
Rewayd Shalash, Dror Michael Solomon, Mor Levi‐Ferber, Henrik von Chrzanowski, Mohammad Khaled Atrash, Barak Nakar, Matan Yosef Avivi, Hagit Hauschner, Aviya Swisa, Alicia Meléndez, Yaron Shav‐Tal, Sivan Henis‐Korenblit   +11 more
wiley   +1 more source

Multiple forms of histone H2B from the nematode Caenorhabditis elegans [PDF]

, 1986
Jacques R. Vanfleteren, S M Van Bun, L. Delcambe, Jozef J. Van Beeumen   +3 more
openalex   +1 more source

Alternate Day Fasting Enhances Intestinal Epithelial Function During Aging by Regulating Mitochondrial Metabolism

Aging Cell, EarlyView.
Alternate day fasting alleviates aging‐induced intestinal epithelial barrier damage by regulating mitochondrial metabolism in small intestinal stem cells. ABSTRACT With advancing age, the decline in intestinal stem cell (ISC) function can lead to a series of degenerative changes in the intestinal epithelium, a critical factor that increases the risk of
Heng Quan, Yao Lu, Yingying Lin, Peng Xue, Yuning Zhang, Yuqi Wang, Weiru Yu, Xiaoya Lin, Wuqi Yang, Cong Lv, Yafei Zhang, Fazheng Ren, Huiyuan Guo   +12 more
wiley   +1 more source

Age-specific nuclear proteins in the nematode worm Caenorhabditis elegans [PDF]

, 1987
Lydie Meheus, Jozef J. Van Beeumen, A. Coomans, Jacques R. Vanfleteren   +3 more
openalex   +1 more source

3D Mitochondrial Structure in Aging Human Skeletal Muscle: Insights Into MFN‐2‐Mediated Changes

Aging Cell, EarlyView.
Changes in mitochondrial structure and dynamics during aging provide a mechanism for the development of age‐related sarcopenia, a condition characterized by muscle mass loss. Through the creation of three‐dimensional models of mitochondria from quadriceps muscle tissue taken from old and young humans, a loss in mitochondrial complexity was observed to ...
Estevão Scudese, Andrea G. Marshall, Zer Vue, Vernat Exil, Benjamin I. Rodriguez, Mert Demirci, Larry Vang, Edgar Garza López, Kit Neikirk, Bryanna Shao, Han Le, Dominique Stephens, Duane D. Hall, Rahmati Rostami, Taylor Rodman, Kinuthia Kabugi, Jian‐qiang Shao, Margaret Mungai, Salma T. AshShareef, Innes Hicsasmaz, Sasha Manus, Celestine N. Wanjalla, Aaron Whiteside, Revathi Dasari, Clintoria R. Williams, Steven M. Damo, Jennifer A. Gaddy, Brian Glancy, Estélio Henrique Martin Dantas, André Kinder, Ashlesha Kadam, Dhanendra Tomar, Fabiana Scartoni, Matheus Baffi, Melanie R. McReynolds, Mark A. Phillips, Anthonya Cooper, Sandra A. Murray, Anita M. Quintana, Nelson Wandira, Okwute M. Ochayi, Magdalene Ameka, Annet Kirabo, Sepiso K. Masenga, Chanel Harris, Ashton Oliver, Pamela Martin, Amadou Gaye, Olga Korolkova, Vineeta Sharma, Bret C. Mobley, Prasanna Katti, Antentor Hinton   +52 more
wiley   +1 more source

GENE INTERACTIONS AFFECTING MUSCLE ORGANIZATION IN CAENORHABDITIS ELEGANS [PDF]

, 1985
Susan J. Brown, Donald L Riddle
openalex   +1 more source

The Proprotein Convertase BLI‐4 Is Required for Axenic Dietary Restriction Mediated Longevity in Caenorhabditis elegans

Aging Cell, EarlyView.
In ADR‐induced longevity in C. elegans, neuronal BLI‐4 processes neuropeptides, which are then released with the assistance of UNC‐31 and GOLG‐2. ABSTRACT Dietary restriction (DR) is a well‐established method for extending lifespan across various species, including C. elegans.
Ping Wu, Lieselot Vandemeulebroucke, Huaihan Cai, Bart P. Braeckman   +3 more
wiley   +1 more source

A pheromone-induced developmental switch in Caenorhabditis elegans: Temperature-sensitive mutants reveal a wild-type temperature-dependent process.

, 1984
James W. Golden, Donald L Riddle
openalex   +1 more source