Heat shock factor-1 alleviates ER-stress in Caenorhabditis elegans. [PDF]
Ahmed S +12 more
europepmc +1 more source
The Effect of Protein Tagging on Aggregation and Phase Separation
ABSTRACT Protein tags are widely used for purification, solubilization, detection, and imaging, yet they can substantially alter protein self‐assembly. This interference is particularly significant for intrinsically disordered proteins and low‐complexity domains, whose aggregation and phase separation are mediated by weak multivalent interactions that ...
Harunobu Saito, Kenji Sugase
wiley +1 more source
BCAS-3 is required for the progression of autophagosome formation to degrade paternal mitochondria in <i>Caenorhabditis elegans</i>. [PDF]
Norizuki T +7 more
europepmc +1 more source
RNAs Associated With Bacterial Outer Membrane Vesicles: Structural Insights Into Surface Composition
This work uncovers a new layer of bacterial communication. We show that RNAs, aided by the Hfq RNA‐chaperone, are not only packed inside Gram negative Outer Membrane Vesicles (OMVs) but can also be embedded in their membranes. This suggests that bacteria may use surface‐exposed RNAs to directly interact with host cells. Overall, our results broaden the
Kevin Mosca +4 more
wiley +1 more source
An epifluorescence microscope design for naturalistic behavior and cellular activity in freely moving Caenorhabditis elegans. [PDF]
Wittekindt SN +4 more
europepmc +1 more source
Intranasal Delivery of Bacterial Extracellular Vesicles Enables RNA Cargo Entry Into the Brain
ABSTRACT Extracellular vesicles (EVs) released by bacteria are potent mediators of host–microbe interactions. They modulate immune responses, deliver functional molecules and influence disease progression. However, whether bacterial EVs can access the brain and functionally affect host cells remains unclear.
Jae Yeong Ha +8 more
wiley +1 more source
Multilayered regulation of longevity in Caenorhabditis elegans. [PDF]
Bong D, Kwon HC, Lee SV.
europepmc +1 more source
GravSorter: a forward-genetics tool for studying gravity response in <i>Caenorhabditis elegans</i>.
Ma H, Raizen DM, Bau HH.
europepmc +1 more source
Neuronal Activity Regulating the Dauer Entry Decision in Caenorhabditis elegans. [PDF]
Prakash SJ +6 more
europepmc +1 more source
ParaHox Genes Revisited: From Gut Patterning to Integrated Axial and Neural Organization in Rotifera
In rotifers, ParaHox genes show a dispersed genomic organization, with Xlox absent across gnathiferans. Exclusive neuronal expression of Gsx and Cdx reveals that ancestral ParaHox genes coordinated neural and epithelial development beyond gut patterning, suggesting an integrated role in early bilaterian body plan organization.
Andreas C. Fröbius +2 more
wiley +1 more source

