Results 241 to 250 of about 118,692 (314)

Sex Determination in Sponges

open access: yesMolecular Reproduction and Development, Volume 93, Issue 6, June 2026.
ABSTRACT Sex determination in Porifera remains one of the least understood aspects of early metazoan biology despite the group's key phylogenetic position. Sponges display exceptional diversity in sexual systems—ranging from stable gonochorism to sequential hermaphroditism and sex reversal—yet lack morphological dimorphism and any discrete gonadal ...
Jose M. Lorente‐Sorolla, Ana Riesgo
wiley   +1 more source

Sequence and structural alignments reveal insights into ANKLE2 evolution and function

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract ANKLE2 is an enigmatic protein with emerging roles in cell division, development, and virus replication. While ANKLE2 orthologs are present in all animals, its domain composition has evolved over time. ANKLE2's two namesake domains, the ankyrin repeat and LEM domains (named for LAP2, Emerin, and MAN1), have clear and defined roles; however ...
Adam T. Fishburn   +8 more
wiley   +1 more source

The role of the nucleus in the control of mitochondrial precursor proteins in yeast

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Mitochondria are essential organelles of eukaryotic cells, with vital roles in energy production, biosynthesis of macromolecules, and intracellular signaling. Their function depends on a complex proteome with proteins targeted to different mitochondrial sub‐compartments.
Kira Ritzenhofen   +3 more
wiley   +1 more source

Biophysical assessment of the molecular mechanisms of Tau aggregation and its role in Alzheimer's disease

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Alzheimer's disease (AD) is characterized by the intracellular aggregation of the microtubule‐associated protein Tau. While the presence of large, insoluble neurofibrillary tangles has long been the primary focus of this research, a paradigm shift in the field now highlights smaller, soluble oligomers as the more neurotoxic Tau species leading
Joshua T. Skrehot, Dmitry Kurouski
wiley   +1 more source

Boron‐10 carriers and their applications in boron neutron capture therapy

open access: yesPrecision Radiation Oncology, Volume 10, Issue 2, Page 205-241, June 2026.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang   +7 more
wiley   +1 more source

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