Results 251 to 260 of about 118,692 (314)

Cryo‐EM structure of ALC1 in an open conformation bound to a PARylated nucleosome

open access: yesActa Crystallographica Section D, Volume 82, Issue 6, Page 683-699, June 2026.
Reanalysis of a publicly available cryo‐EM dataset identifies a new conformation of the oncogenic chromatin remodeler ALC1/CHD1L bound to a PARylated nucleosome. This new structure reveals the position of the macro domain in the complex, and may help to understand the large conformational change leading to the activation of ALC1.Nucleosomes are the ...
Hannah R. Bridges   +3 more
wiley   +1 more source

Predator–Microbe Dynamics Inform Strategies for Robust Synthetic Community Assembly

open access: yesEnvironmental Microbiology, Volume 28, Issue 6, June 2026.
This Review introduces ecological principles of predator–prey interactions as a new dimension in SynCom design. By linking microbial defence traits, encounter dynamics, and adaptive buffering, it outlines a framework for constructing predator‐resistant synthetic communities with enhanced resilience, stability, and functional performance under natural ...
Eleonora Egidi, Uffe N. Nielsen
wiley   +1 more source

Genomic Map of Escherichia coli and Single Nucleotide Polymorphism Markers in Colorectal Cancer

open access: yesMicrobial Biotechnology, Volume 19, Issue 6, June 2026.
This study identified colorectal cancer‐associated SNPs in Escherichia coli using PacBio full‐genome sequencing, establishing a highly accurate SNP‐based model for non‐invasive colorectal cancer risk prediction. ABSTRACT Gut microbial single nucleotide polymorphisms (SNPs) offer stable, specific genetic markers for disease diagnosis.
Yang Xi   +10 more
wiley   +1 more source

Loss of SMARCAD1 Mitigates Tauopathy

open access: yesAging Cell, Volume 25, Issue 6, June 2026.
Using genetics approaches in a C. elegans transgenic model of tauopathy, we uncover a role for the homolog of human SMARCAD1, a regulator of chromatin dynamics. ABSTRACT Tauopathies are neurodegenerative diseases characterized by the accumulation of misfolded tau protein and include Alzheimer's disease (AD) and related dementia disorders.
Vaishnavi S. Jadhav   +7 more
wiley   +1 more source

Lipid Analysis in Live <i>Caenorhabditis elegans</i> Using Solution-State NMR Spectroscopy. [PDF]

open access: yesBio Protoc
Guastaferri FV   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy