Results 191 to 200 of about 168,979 (308)

Acute caffeine and carbohydrate strategies for fatigue-related sport-specific performance in team-sport athletes: a systematic review and multilevel meta-analysis. [PDF]

J Int Soc Sports Nutr
Xie S, Wen X.
europepmc   +1 more source

Safety, Tolerability, Pharmacokinetics and Exploratory Pharmacodynamics of Melanin‐Concentrating Hormone Receptor‐1 Antagonist RGH‐706 in Healthy and Overweight or Obese Men

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim This Phase 1 program evaluated the safety, tolerability, pharmacokinetics and exploratory pharmacodynamics of the novel melanin‐concentrating hormone receptor‐1 antagonist RGH‐706. Methods Study A was a first‐in‐man, randomized trial comprising a double‐blind, placebo‐controlled single‐ascending‐dose part (0.1–162.5 mg) and a two‐way ...
Thomas Brevig, Borbála Szepes, Zsófia Borbála Dombi, Gabriella Magyar, Zoltán Juhász, Margit Kapás, Éva Cseh, Zsuzsa Hegedűs, Tibor Farkas, Zsuzsanna Kiss, Balázs Szatmári   +10 more
wiley   +1 more source

Effects of Maternal Caffeine Exposure During Gestation on Neurobehavior, Glucose Metabolism and Circadian Rhythm in Offspring Rats. [PDF]

Toxics
Sun M, Pan H, Yang G, Zhang Y, Li J, Li X, Zhu W.   +6 more
europepmc   +1 more source

Sleep Architecture, Glucose Regulation and Subclinical Cardiovascular Risk in Adults With Type 1 Diabetes Mellitus: A Wearable Sleep Tracking and Continuous Glucose Monitoring Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Objective To investigate the associations of wearable‐derived sleep architecture with CGM‐derived glucose metrics, HbA1c and markers of subclinical atherosclerosis in adults with Type 1 diabetes mellitus (T1DM) in the CORDIA study. Study Design and Methods One hundred and seventy‐nine adults (79 women) with long‐standing T1DM wore an Apple ...
Natália Marhefková, Viktória Mikušová, Robert Roland, Michal Pazderník, Peter Wohlfahrt, Peter Novodvorský, Martin Sládek, Alena Sumová, Martin Haluzík, Michal Dubský   +9 more
wiley   +1 more source

High-dose caffeine reduces neurite branching and alters expression of selected genes in immature primary rat cortical and hippocampal cell cultures. [PDF]

IBRO Neurosci Rep
Bjurling SFL, Stam F, Nylander E, Grönbladh A.   +3 more
europepmc   +1 more source

Using grape seed extract to reduce erosive potential of drinks

European Journal of Oral Sciences, EarlyView.
Abstract The aim of this study was to verify whether supplementation of grape seed extract (GSE) to different erosive beverages reduces their erosive potential on dentine in vitro. One‐hundred dentine specimens were randomly assigned to 5 groups (n = 20/group): control‐deionized water, 1%‐citric acid, Red Bull, Coca‐Cola, and Powerade.
Samira Helena Niemeyer, Jessica Schuler, Sara Kim Plüss, Tommy Baumann, Florian Just Wegehaupt, Thiago Saads Carvalho   +5 more
wiley   +1 more source

Comparative Analysis of the Central Nervous System Safety Pharmacology Profiles of Caffeine and Taurine in Male and Female Mice Using a Modified Irwin Test. [PDF]

Prev Nutr Food Sci
Cho SH, Zheng J, Kim BH, Kim M, Doo M, Ha JH.   +5 more
europepmc   +1 more source

The epigenetic landscape of skeletal muscle in response to exercise and aging

The FEBS Journal, EarlyView.
Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley   +1 more source

Acute Effects of Caffeine on Choroidal Structure and Vascularity in Healthy Young Adults: A Time-Resolved OCT and OCT-Angiography Study. [PDF]

Nutrients
D'Aniello E, Vitiello L, De Bernardo M, Lee D, De Pascale I, La Padula G, Gallo S, Pellegrino A, Rosa N.   +8 more
europepmc   +1 more source

Functional and transcriptomic analyses in Neurospora crassa reveal a crucial role for the N‐glycoprotein deglycosylation process in fungal homeostasis

The FEBS Journal, EarlyView.
In Neurospora crassa, a cytosolic GH18 endo‐β‐n‐acetylglucosaminidase (ENGase) functions as an active deglycosylating enzyme. Deletion of this severely alters tolerance to multiple stress conditions and causes extensive transcriptomic reprogramming, including upregulation of a GH20 exo‐β‐n‐acetylhexosaminidase under ER stress, indicating that N. crassa
Anastasios Samaras, Tanim Jabid Hossain, Magnus Karlsson, Georgios Tzelepis   +3 more
wiley   +1 more source