Results 191 to 200 of about 164,322 (311)

Controlled breathing and heart rate variability biofeedback for substance use‐related outcomes: A systematic review and meta‐analysis

open access: yesAddiction, EarlyView.
Abstract Background and aim Substance use disorders (SUDs) contribute significantly to global social and economic burden. Breathing‐based interventions offer a low‐cost, scalable adjunct or alternative to traditional treatment, yet their effects on substance use‐related outcomes has not been systematically evaluated.
Ariel Dart Roxburgh   +7 more
wiley   +1 more source

Proof‐of‐concept trial of PP‐01 for mitigating cannabis withdrawal syndrome in participants with cannabis use disorder

open access: yesThe American Journal on Addictions, EarlyView.
Abstract Background and Objectives Cannabis withdrawal symptoms can be severe and protracted, significantly impeding the ability to abstain from cannabis use, resulting in failed quit attempts and relapse. This clinical trial evaluated safety and efficacy of PP‐01, a novel dual‑mechanism of action, investigational agent, for mitigating cannabis ...
Ashley F. Slagle   +4 more
wiley   +1 more source

Lactate‐Responsive Glycogen Dynamics Are Associated With Bull Sperm Motility and Fertilization Under Glucose‐Limited Conditions

open access: yesAndrology, EarlyView.
ABSTRACT Background Mammalian sperm need to undergo hyperactivation, capacitation, and acrosome reaction to achieve fertilization competence. However, the female reproductive tract presents contrasting metabolic environments. The uterus is glucose‐rich, and the oviduct is lactate‐rich and glucose‐limited.
Md Faizul Hossain Miraz   +5 more
wiley   +1 more source

Effects of Acute Caffeine Ingestion on Morning Temperature, Mood, Reactive Agility and Cognitive Measures in Males: A Standardized Approach. [PDF]

open access: yesNutrients
Edwards BJ   +8 more
europepmc   +1 more source

Safety pharmacology of acute mescaline administration in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber   +4 more
wiley   +1 more source

A qualitative investigation of the lived experiences of adults with anxiety and related disorders and ADHD: Interconnectedness of symptoms and implications for improving care

open access: yesBritish Journal of Clinical Psychology, EarlyView.
Abstract Background Attention‐deficit/hyperactivity disorder (ADHD) is highly prevalent in adults with anxiety and related disorders (ARDs). Quantitative research on this clinical population is mixed, with some studies suggesting that anxiety is protective against some symptoms of ADHD and others in which co‐occurring ARDs and ADHD are linked to poorer
Arij Alarachi   +3 more
wiley   +1 more source

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