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The caffeine contracture test for malignant hyperthermia: caffeine citrate, caffeine benzoate or caffeine free base?

Acta Anaesthesiologica Scandinavica, 1991
The aim of the present study was to investigate whether the three different caffeine preparations — caffeine citrate, caffeine benzoate and the free base — used forin vitrodiagnosis of malignant hyperthermia susceptibility — produced the same amount of contracture in rat diaphragm.
James J. A. Heffron   +2 more
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Caffeine and headaches

Current Pain and Headache Reports, 2007
Caffeine is the most widely consumed psychostimulant drug. It is a potent antagonist of adenosine receptors at dosages consistent with common dietary intake. With infrequent exposure, caffeine may act as an analgesic for headache or an adjuvant for the actions of other analgesics. With chronic repetitive intake, caffeine is associated with an increased
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Caffeine: An Update

Drug and Chemical Toxicology, 1981
While the total annual volume of caffeine has increased over the years, the actual per capita daily intake has not. This is based on the fact that the quantity of caffeine in a soft drink is about the same or, in the case of diet drinks, less than in 1961 when the original GRAS (Generally Recognized as Safe) determinations were made.
Bernard L. Oser, Richard A. Ford
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Extraction of caffeine

Journal of Chemical Education, 1972
Much greater yields can be obtained by extracting caffeine from No-Doz tablets than coffee or tea.
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Caffeine and tremor

Neurology, 1987
Two percent of normal controls noted that drinking coffee made their hands shaky. Eight percent of essential tremor and 6% of Parkinson's disease patients thought that coffee worsened their tremor. In formal tests, a single oral dose of caffeine (325 mg) did not increase physiologic, essential tremor, or parkinsonian tremor at 1, 2, or 3 hours after ...
Gregory Herbster   +2 more
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Caffeine and the eye

Survey of Ophthalmology, 2019
Caffeine, a popular psychostimulant that acts as an adenosine receptor antagonist, is the most widely used drug in history, consumed daily by people worldwide. Knowledge of the physiological and pathological effects of caffeine is crucial in improving public health because of its widespread use.
Helen V. Danesh-Meyer, Jinny J. Yoon
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Metamorphosis of caffeine hydrate and anhydrous caffeine

Journal of the Chemical Society, Perkin Transactions 2, 1997
The phase stability, interconversion and physicochemical characterisation of caffeine (1,3,7-trimethylpurine-2,6-dione) hydrate and anhydrous caffeine relate to the strength of the available hydrogen-bonds. A hydrogen-bonded T-branched spine of hydrate molecules establishes a weak lattice bond for the caffeine hydrate which, under ambient conditions ...
E.E. Lawson   +4 more
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Caffeine and Performance

International Journal of Sport Nutrition, 1995
Caffeine ingestion (3-9 mg/kg body weight) prior to exercise increases performance during prolonged endurance exercise and short-term intense exercise lasting ~5 min in the laboratory. These results are generally reported in well-trained elite or recreational subjects.
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Caffeine and pain [PDF]

open access: possiblePain, 2011
abstract 2010 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved. 1. IntroductionCaffeine is widely consumed for its central nervous systemstimulant effects such as increased alertness and decreased fatigue.It is present in a variety of beverages (coffee, tea, energy drinks)and some foods (chocolate ...
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The pharmacology of caffeine

1987
Caffeine is a natural constituent of more than 60 plant species and as such is present in the human diet through drinks based on plant extracts. It has also been used as a flavoring agent in food (baked goods, dairy desserts, puddings and fillings, candy) and beverages (Dr.
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