Results 131 to 140 of about 44,889 (252)

Cannabinoid and adenosine A2A receptor crosstalk regulates postnatal and adult hippocampal neurogenesis

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and purpose Adult neurogenesis is a tightly regulated process affected by both cannabinoid receptors (CB1 and CB2) and adenosine 2A (A2A) receptors, both of which modulate neural progenitor cell activity. While emerging evidence suggests an interaction between these neuromodulatory systems, the extent and mechanism of their interplay in ...
Rui S. Rodrigues   +8 more
wiley   +1 more source

Inhibition of late sodium current prevents pathological hyperactivation of calcium/calmodulin‐dependent protein kinase IIδ in a murine model of acute doxorubicin‐related cardiotoxicity

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Doxorubicin (DOX) is a highly effective anthracycline, whose clinical application for cancer is limited by cardiotoxicity. The mechanisms underlying doxorubicin‐induced toxic cardiomyopathy (DICM) involve electrophysiological remodelling with intracellular Na+ overload because of increased late INa and hyperactivation of
Anna‐Lena Feder   +7 more
wiley   +1 more source

Cardiovascular Autonomic Neuropathy and Indices of Heart Failure in Type 2 Diabetes: The CANCAN Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To quantify the association between cardiovascular autonomic neuropathy (CAN) and heart failure (HF) in individuals with type 2 diabetes (T2D). Materials and Methods Two hundred T2D individuals were recruited from two Danish outpatient clinics between 2021–2024. CAN was defined by abnormal cardiovascular autonomic reflex test results.
Jonas R. Schaarup   +7 more
wiley   +1 more source

Impact of Sleep Quality on Oral Surgical Complications in Dental Interns

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Introduction Many dentistry students suffer from intense stress, insomnia, and anxiety throughout their education, especially when they start clinical practice. This study aims to evaluate the effects of sleep quality on complication rates among 5th‐grade dentistry students undergoing oral and maxillofacial surgery internships.
Tolgahan Kara   +2 more
wiley   +1 more source

Caffeine consumption patterns, motivations, and adverse effects among Brazilian esports players: a cross-sectional study. [PDF]

open access: yesJ Int Soc Sports Nutr
Abhulime EWM   +5 more
europepmc   +1 more source

Personalized machine learning prediction of next‐day migraine persistence using digital headache diary data

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Migraine is a disabling neurological disorder with substantial interindividual variability. Predicting whether an ongoing migraine attack will persist into the following day remains challenging. We evaluated the feasibility and predictive performance of personalized machine learning models for predicting next‐day migraine
Ya‐Hsiu Tsai   +7 more
wiley   +1 more source

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