Results 41 to 50 of about 288,938 (268)
Animal Welfare and Food Safety Aspects of Confining Broiler Chickens to Cages
Animals, 2013 In most areas of the world, broiler chickens are raised in floor systems, but cage confinement is becoming more common. The welfare of broiler chickens in cages is affected by movement restriction, poor bone strength due to lack of exercise, and ...
Sara Shields, Michael Greger
doaj +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Communications, 2014 The aim of this paper is to detail the creation of a large tapered roller bearing model with flexible body cages in the Adams program suite for subsequent dynamic analysis and to obtain information about kinematic and dynamic relationships of steel and ...
Robert Kohar, Slavomir Hrcek
doaj +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Housing and Management Practices on 33 Pullet Farms in Canada
Animals, 2019 Although Canada is one of the first to provide guidelines on pullet rearing in a new Code of Practice which came into effect in March 2017, little information is available about the housing and management of pullets on Canadian farms.
Nienke van Staaveren +5 more
doaj +1 more source
Caging and Uncaging Genetics [PDF]
PLOS Biology, 2016 It is important for biology to understand if observations made in highly reductionist laboratory settings generalise to harsh and noisy natural environments in which genetic variation is sorted to produce adaptation. But what do we learn by studying, in the laboratory, a genetically diverse population that mirrors the wild?
Little, Tom J, Colegrave, Nick
openaire +4 more sources
FastNano Liquid: An Automated Platform for Small‐Angle X‐ray Scattering‐Based Materials Discovery
Advanced Engineering Materials, EarlyView.We present FastNano Liquid, an automated small‐ and wide‐angle X‐ray scattering platform for the combined synthesis and characterization of (nano)materials. The platform is coupled to varied reactor workflows for both in situ studies of reaction kinetics and ex situ screening of synthesis conditions to support machine learning‐guided exploration ...
Pierre‐Baptiste Flandrin +16 more
wiley +1 more source
Mathematics of the Faraday Cage [PDF]
SIAM Review, 2015 Summary: The amplitude of the gradient of a potential inside a wire cage is investigated, with particular attention to the 2D configuration of a ring of \(n\) disks of radius \(r\) held at equal potential. The Faraday shielding effect depends upon the wires having finite radius and is weaker than one might expect, scaling as \(|\log r|/n\) in an ...
S. Jonathan Chapman +2 more
openaire +3 more sources