Results 81 to 90 of about 11,542 (205)

Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management

Clinical Endocrinology, Volume 105, Issue 3, Page 271-284, September 2026.
ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu, Yue Li, Meng Sun, Yulin Li, Panpan Li, Hui Zou   +5 more
wiley   +1 more source

Managing Problem‐Framing in Public Procurement of Innovation: The Role of Control

R&D Management, Volume 56, Issue 4, Page 641-656, September 2026.
ABSTRACT Public procurement is increasingly employed as an instrument to stimulate innovation. However, little is known about how public actors manage problem‐framing processes in the context of public procurement of innovation. Drawing on the literature of problem‐framing and public procurement, we conduct an exploratory case study of three innovation
Ann Højbjerg Clarke, Outi Keränen, Sari Laari‐Salmela, Pauliina Ulkuniemi   +3 more
wiley   +1 more source

A new model for contact angle hysteresis of superhydrophobic surface

AIP Advances, 2019
Contact angle hysteresis (CAH) is essential to characterize the wetting properties of a surface. But its underlying causes are not yet understood. A model relating to CAH is presented through mathematical deduction.
Jiyuan Zhu, Xuanjun Dai
doaj   +1 more source

Biosimilar Rituximab in ANCA‐Associated Vasculitis Compared to the Originator: A Multicenter Cohort Study

ACR Open Rheumatology, Volume 8, Issue 8, August 2026.
Objective To evaluate the six‐month effectiveness and safety of rituximab biosimilars compared to the originator in granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), and outcomes following originator to biosimilar switching. Methods We recruited adults with GPA or MPA treated with the rituximab originator or a biosimilar for ...
Arielle Mendel, Lillian Barra, Hassan Behlouli, Sasha Bernatsky, Alison H. Clifford, Jan Willem Cohen Tervaert, Natasha Dehghan, Aurore Fifi‐Mah, Jean‐Paul Makhzoum, Rosalie‐Sélène Meunier, Nataliya Milman, Medha Soowamber, Elaine Yacyshyn, Nader Khalidi, Christian Pagnoux   +14 more
wiley   +1 more source

Quality indicators for safe and effective medication use in long‐term care facilities: A modified Delphi study

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2657-2671, August 2026.
Aim This modified Delphi study aimed to achieve expert agreement on quality indicators (QIs) suitable for application at the population level, to evaluate quality use of medications and pharmacist services in long‐term care facilities (LTCFs). Methods We conducted a two‐round modified online Delphi study with a multidisciplinary panel of Australian ...
Daria S. Gutteridge, Sara Javanparast, Annabel H. Calder, Gillian E. Caughey, Andrew C. Stafford, Gregory M. Peterson, Maria C. Inacio, Peter D. Hibbert, Elizabeth Manias, Jodie B. Hillen, Janet K. Sluggett   +10 more
wiley   +1 more source

AI‐Powered Gradient Echo Plural Contrast Imaging (AI‐GEPCI)—A Comprehensive Neurological Protocol From a Single MRI Scan

Journal of Magnetic Resonance Imaging, Volume 64, Issue 2, Page 346-358, August 2026.
ABSTRACT Background MRI is essential for diagnosing and monitoring neurological diseases. Conventional protocols require multiple sequences to obtain complementary contrasts, increasing scan time, cost, and tolerability. Generating multiple contrasts from a single acquisition may streamline workflow while maintaining clinical utility.
Jeramy Lewis, Manu S. Goyal, Gregory F. Wu, Yuyang Hu, Alexander L. Sukstanskii, Satya V. V. N. Kothapalli, Anne H. Cross, Ulugbek Kamilov, Dmitriy A. Yablonskiy   +8 more
wiley   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

Phytotherapy Research, Volume 40, Issue 8, Page 4880-4897, August 2026.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Insulin Resistance Emerges Early After Glucocorticoid Treatment in Adult Patients With 21‐Hydroxylase Deficiency

Journal of Diabetes, Volume 18, Issue 8, August 2026.
In adults with 21‐hydroxylase deficiency, ongoing glucocorticoid therapy, especially dexamethasone, was the main risk factor for insulin resistance. New‐onset insulin resistance emerged early, highlighting the need for metabolic monitoring within the first 1–2 years of treatment. ABSTRACT Background Metabolic disorders, particularly insulin resistance (
Chenchen Dong, Wencui Wang, Sichang Zheng, Lingxin Deng, Rulai Han, Weiqing Wang, Guang Ning, Shouyue Sun, Lei Ye   +8 more
wiley   +1 more source

Reproductive and fertility challenges in adolescents with congenital adrenal hyperplasia

Frontiers in Adolescent Medicine
Congenital adrenal hyperplasia (CAH) carries reproductive implications that begin to manifest in childhood and adolescence and extend into adulthood. This review examines the reproductive challenges that emerge during adolescence in individuals with CAH ...
Lea Tschaidse, Matthias K. Auer, Hanna F. Nowotny, Nicole Reisch   +3 more
doaj   +1 more source

The Relationship Between Polycystic Ovary Syndrome (PCOS) and Depression

Clinical Endocrinology, Volume 105, Issue 2, Page 131-140, August 2026.
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder, frequently accompanied by psychological comorbidities including depression. The aim of this narrative review is to summarise the latest research regarding potential contributors to and underpinning mechanisms of this relationship.
Asimina I. Karampela, Maralyn Druce
wiley   +1 more source