Results 121 to 130 of about 14,518 (334)
Descrição histológica e ultra-estrutural da absorção de óleo de soja pelo intestino do jacaré do pantanal (Caiman yacare, Daudin, 1802). [PDF]
, 2014 Ricardo Moraes Borges
openalex +1 more source
Covalent Reprogramming of Kinase Binders to Modulate Protein Abundance
Advanced Science, EarlyView.Electrophilic remodeling of a broad‐spectrum kinase binder reveals how subtle chemical changes reprogram protein fate. An acrylamide analog of a multi‐kinase binder selectively stabilizes Aurora kinase A (AURKA) by suppressing its ubiquitination, while a short‐linker variant converts this stabilizer into a degrader.
Chen Mozes +4 more
wiley +1 more source
Avian Conservation and Ecology, 2021 Seabirds, being long-lived top-level marine predators, are often considered to be valuable environmental indicators. With growing evidence of seabird declines worldwide, it is essential to monitor changes in populations and determine drivers of change ...
April J. Burt +8 more
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Dissecting Pirtobrutinib Resistance in Mantle Cell Lymphoma Through Single‐Cell Multi‐Omics
American Journal of Hematology, EarlyView.ABSTRACT Pirtobrutinib (PBN), a non‐covalent BTK inhibitor, has been approved by the FDA for relapsed/refractory mantle cell lymphoma (MCL); however, resistance to PBN has been observed. To dissect the molecular dynamics driving PBN resistance, we performed integrative single‐cell multi‐omic profiling (scRNA‐seq, scATAC‐seq, and scDNA‐seq) on ...
Fangfang Yan +10 more
wiley +1 more source
WG1N5327 - Medical image database for lossless codec evaluation [PDF]
, 2010 This document presents the CAIMAN Project medical image database for JPEG commitee evaluation works purposes.This document describes the CAIMAN ANR project contribution on medical images to be considered for AIC.
Babel, Marie +4 more
core +2 more sources
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Autosomal recessive loss‐of‐function variants in PPP1R13L cause an ultra‐rare cardiocutaneous syndrome characterized by rapidly progressive arrhythmogenic cardiomyopathy (ACM). PPP1R13L encodes iASPP, which has two potentially overlapping mechanisms driving ACM as both a regulator of NFκB‐mediated inflammation and a binding partner within the ...
Aaron Renberg +9 more
wiley +1 more source
Algorithms Implemented for Cancer Gene Searching and Classifications [PDF]
Understanding the gene expression is an important factor to cancer diagnosis. One target of this understanding is implementing cancer gene search and classification methods.
Al-Rajab, Murad, Lu, Joan
core
Animal Models and Experimental Medicine, EarlyView.Transcriptome sequencing identified secreted phosphoprotein 1 (SPP1) as a crucial target through which methylophiopogonanone A (MOA) ameliorates pulmonary fibrosis. Molecular docking and microscale thermophoresis (MST) assays confirmed a favorable binding affinity between MOA and SPP1.
Fan Yang +10 more
wiley +1 more source
Revista de Biología Tropical, 2013 The Paraguayan caiman (Caiman yacare) is the main Caimaninae species occurring in the Brazilian Pantanal Wetland. Despite the relative availability of works focused on biology and conservation of the Paraguayan caiman, almost nothing is known about its ...
Fernando L. Sicuro +3 more
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