Results 101 to 110 of about 14,518 (334)

KCNJ2 is Required for NLRP3 Inflammasome Activation That Drives Allergic Airway Inflammation and Remodeling

Advanced Science, EarlyView.
This study aims to evaluate the impact of the potassium channel KCNJ2 on asthma development. KCNJ2 promotes NLRP3 inflammasome activation through both Ca2+ influx and K+ efflux in airway epithelial cells, which drives allergic airway inflammation and remodeling, suggesting a promising therapeutic target for asthma.
Yachao Cui, Shumei Wu, Yang Peng, Yiqi Liu, Li Che, Shiying Chen, Feng Zhang, Dajiang Qin, Shiyue Li, Pixin Ran, Wenguang Yin   +10 more
wiley   +1 more source

Efeito do fogo sobre a estrutura e composição da comunidade vegetal em paleo-levees, Pantanal, Brasil

Biodiversidade Brasileira
O Pantanal é um bioma brasileiro dependente do fogo. Tanto o pulso de inundação anual como os eventos de fogo são importantes drivers que condicionam a estrutura das suas formações vegetais.
Rosa Helena da Silva, Alexandre de Matos Martins Pereira, Maxwel Oliveira da Rosa, Anny Grazielly da Silva Arruda, Edna Scremin-Dias, Felipe Augusto Dias , Roberto Luiz Leme Klabin , Mario Buhrke Haberfeld, Luciana Fabbri, Julia de Matos Nogueira, Arnildo Pott, Rafael Arruda, Geraldo Alves Damasceno Junior   +12 more
doaj   +1 more source

Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) activate NF‐κB and provoke inflammation that limits therapeutic delivery. By encapsulating selective NF‐κB inhibitors within LNPs, localized suppression of inflammatory signaling is achieved without compromising mRNA expression.
Carolann L. Espy, Jichuan Wu, Serena Omo‐Lamai, Liuqian Wang, Fengyi Dong, Aleksa Milosavljevic, Sarah O'Neill, Taylor Brysgel, Yufei Wang, Michael Zaleski, Emily Wolfe, Rhea Maheshwari, Manthan Patel, Dirk Trauner, Jia Nong, Zhicheng Wang, Jacob S. Brenner   +16 more
wiley   +1 more source

Cambios en la estructura poblacional del caimán, Caiman crocodilus (Crocodylia: Alligatoridae) y su posible relación con el cambio climático, en Caño Negro, Costa Rica

Cuadernos de investigación UNED, 2017
El caimán, Caiman crocodilus, es importante ecológica y económicamente en algunas áreas de Latinoamérica. En Costa Rica no es abundante y existe poca información de su población.
J Manuel Aranda-Coello
doaj   +1 more source

Crocodiles - the Singular Beast in the Renaissance Cabinet

, 2017
Stuffed crocodiles often predominated many famous cabinets, hanging in the center of the ceiling. Crocodilians are the largest reptiles and the largest predator that spends time on land.
Zhang, Peter
core  

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

Advanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman, Carla Alvarez Rivas, Aashish Srivastava, Nora Marek, Kamal Mustafa, Alpdogan Kantarci   +5 more
wiley   +1 more source

Cranial shape variation in jacarean caimanines (Crocodylia, Alligatoroidea) and its implications in the taxonomic status of extinct species: The case of Melanosuchus fisheri [PDF]

, 2018
Cranial shape variation in jacarean caimanines (Crocodylia, Alligatoroidea) and its implications in the taxonomic status of extinct ...
Adams, Aguilera, Anderson, Barbosa-Rodrigues, Benson, Bocquentin-Villanueva, Bona, Bona, Bona, Bona, Bookstein, Bravard, Brazaitis, Brochu, Brochu, Brochu, Brochu, Brochu, Drake, Dryden, Fernandez Blanco, Foth, Foth, Foth, Gray, Gunz, Hammer, Hammer, Hastings, Hastings, Hrbek, Jackson, Klingenberg, Klingenberg, Korkmaz, Kälin, Linnaeus, Medina, Monteiro, Mook, Oaks, Okamoto, Pearcy, Pierce, Piras, Poe, Rohlf, Rovereto, Salas-Gismondi, Scheyer, Scheyer, Stubbs, Sánchez-Villagra, Thorbjarnarson, Watanabe, Wilberg, Wilkinson, Young, Zelditch   +58 more
core   +4 more sources

PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu, Shule Zhang, Ruofan Du, Lina Kang, Guodong Zhao, Xue Bao, Haochi Yang, Ziqing Xie, Tianyu He, Huiyong Sun, Haiping Hao, Lijuan Cao   +11 more
wiley   +1 more source

Illegal trade of crocodylians in Colombia: Spatiotemporal dynamics and implications on conservation efforts

Conservation Science and Practice
Crocodylian conservation efforts have encountered significant obstacles from species overhunting to negative local perception. While conservation strategies such as sustainable use have helped the recovery of several crocodylian species around the world,
Edison D. Bonilla‐Liberato, Maria C. Ojeda‐Rojas, Venetia Briggs‐Gonzalez, Frank J. Mazzotti, Sergio A. Balaguera‐Reina   +4 more
doaj   +1 more source

Habitat selection, parasites and injuries in Amazonian crocodilians

, 1985
Caiman crocodilus is found most frequently in relatively warm, shallow or grassy areas in the larger rivers, lakes and canals of Amazonia. The habitats that it uses are increasing in area because of human activities.
Magnusson, W.
core