Results 81 to 90 of about 5,415 (251)

Similarity‐Enhanced Representation Learning of Non‐Canonical Amino Acids for Therapeutic Peptide Modeling

Advanced Science, EarlyView.
Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu, Lesong Wei, Jianmin Wang, Yuanpeng Xiong, Ruochi Zhang, Yu Wang, Chao Zha, Qiangcheng Zeng, Xin Gao   +8 more
wiley   +1 more source

Poblaciones de babillas (caiman crocodilus) y caimán negro (melanosuchus niger) en la reserva biológica del abufari, amazonas, Brasil

Revista Colombiana de Ciencia Animal Recia, 2010
En el presente estudio fueran investigadas la densidad, tallas de la población y la utilización de los ambientes por Melanosuchus niger y Caiman crocodilus en la Reserva Biológica de Abufari, situada en el bajo río Purus.
JACKSON PANTOJA-LIMA, HENRIQUE REBÊLO, GEORGE, CARLOS BRITO PEZZUTI   +2 more
doaj   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

Advanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan   +10 more
wiley   +1 more source

Adaptive Network Stabilization Despite Profound Structural Reorganization in Human Organotypic Cultures

Advanced Science, EarlyView.
Adult human organotypic cortical slices undergo marked neuronal loss, laminar disruption, and glial activation, yet their network activity progressively stabilizes after a variable period. Electrophysiology, longitudinal calcium imaging, and quantitative histology show that structurally remodeled human circuits show adaptive capacity resulting in ...
Estilla Zsófia Tóth, Rebeka Stelcz, Réka Bod, Ábel Petik, Eszter Juhász, Kinga Tóth, Liza Szalai, Nour Essam, Fanni Somogyi, Beatrix Kovács, Amirmahdi Mojtahedzadeh, Attila György Bagó, Loránd Erőss, Péter Orbay, Johanna Petra Szabó, Dániel Fabó, Boglárka Hajnal, Bence Rácz, Daniel Hillier, István Ulbert, Lucia Wittner   +20 more
wiley   +1 more source

Efeito do fogo sobre a estrutura e composição da comunidade vegetal em paleo-levees, Pantanal, Brasil

Biodiversidade Brasileira
O Pantanal é um bioma brasileiro dependente do fogo. Tanto o pulso de inundação anual como os eventos de fogo são importantes drivers que condicionam a estrutura das suas formações vegetais.
Rosa Helena da Silva, Alexandre de Matos Martins Pereira, Maxwel Oliveira da Rosa, Anny Grazielly da Silva Arruda, Edna Scremin-Dias, Felipe Augusto Dias , Roberto Luiz Leme Klabin , Mario Buhrke Haberfeld, Luciana Fabbri, Julia de Matos Nogueira, Arnildo Pott, Rafael Arruda, Geraldo Alves Damasceno Junior   +12 more
doaj   +1 more source

Growth rates of black caiman (Melanosuchus niger) and spectacled caiman (Caiman crocodilus) from two different Amazonian flooded habitats

, 2013
Rates of growth and survival in wild populations are affected by the physical environment, biotic interactions, and density-dependent processes, such as growth and fecundity.
Silveira, Ronis da, Thorbjarnarson, John B., Campos, Zilca M.S., Magnusson, William Ernest   +3 more
core   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

Caiman meat from the Pantanal (Caiman yacare): characterization, obtaining mechanically separated meat and technological application

, 2021
A produção de jacaré do Pantanal (Caiman yacare) em cativeiro, no Brasil, tem sido explorada comercialmente para obtenção de carne (cortes comerciais) e pele, com alta valorização de mercado nacional e internacional.
Paiva, Gilmar Borges de
core  

Caiman yacare distribution

, 2020
Supplementary material for research: Assessing the role of protected areas over the Yacare caiman geographic distribution under current and future climate conditions in ...
Rodriguez-Cordero, A (via Mendeley Data)
core   +1 more source

Developmentally Guided Differentiation of Ventral Midbrain Dopaminergic Cells Validated in Proteopathy‐Based Parkinson's Disease Models

Advanced Science, EarlyView.
A developmentally guided protocol reproducibly specifies EN1‐positive ventral midbrain dopaminergic (vmDA) progenitors from human pluripotent stem cells and yields functional vmDA neurons. Optogenetic induction of α‐synuclein aggregation elicits selective degeneration of TH‐positive neurons in 2D cultures and 3D neurospheroids, while transplanted ...
Heechang Moon, Heejeong Kim, Elliot H. Lee, Hanseul Kim, Ji Hun Kim, Huisu Jeong, Jiwon Cheon, Ga Ram Jeong, Byoung Dae Lee, Jae‐Won Cho, Soo‐Jin Oh, Yunjong Lee, Yohan Oh   +12 more
wiley   +1 more source