Results 171 to 180 of about 14,518 (334)

Targeted senotherapy improves electrographic and behavioral outcomes in a mouse model of temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Current pharmacotherapy for temporal lobe epilepsy (TLE) is limited to symptomatic treatment and leaves approximately one third of patients with inadequate seizure control. Discovering disease‐modifying targets is an unmet clinical need. We have previously identified senescent cells (SCs) as one such target. Many drugs that eliminate
David J. McFall, Abbas I. Hussain, Michelle Cho, Patrick A. Forcelli   +3 more
wiley   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Carcinology in The Natural History Museum, London; the brachyuran crab collections and their curation from 1813-1904 (Leach to Caiman)

, 1991
R. W. Ingle
openalex   +1 more source

The History of Tipping - From Sixteenth-Century England to United States in the 1910s [PDF]

Tipping is a multi-billion-dollar phenomenon that challenges the traditional assumption of selfish economic agents who have no feelings and do not care about social norms.
Ofer H. Azar
core  

CCL26‐Mediated Modulation of Endothelial Secretome by Hypoxia‐Induced Tumor‐Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Tumor cells adapt to hypoxia by releasing hiTDExs enriched with bioactive molecules that modulate endothelial behavior and promote tumor progression. This study aimed to characterize how hypoxia‐induced HNSCC exosomes reshape the endothelial secretome and contribute to metastatic potential.
Ozel Capik, Sevil Tekman, Betul Gundogdu, Ahsen Kilic, Rumeysa Polat, Omer Aydin, Omer Faruk Karatas   +6 more
wiley   +1 more source

Electron microscopic studies on the ultrastructure of ameloblasts during amelogenesis in Caiman Cro-codilus

, 1976
Yasuo Yamashita
openalex   +2 more sources

Histomorphological changes in testes of broad‐snouted caimans (Caiman latirostris) associated with in ovo exposure to endocrine‐disrupting chemicals [PDF]

, 2015
Milena Durando, Guillermina Canesini, Laura L. Cocito, G.H. Galoppo, Marcelo A. Zayas, Enrique H. Luque, Mónica Muñoz‐de‐Toro   +6 more
openalex   +1 more source

Caiman Lizards in the Wild [PDF]

, 1998
B. Draut, T. Léricolais
openalex  

Efeito da temperatura no desenvolvimento de filhotes de jacare-de-papo-amarelo, >i<Caiman latirostris>/i< (Daudin, 1802) em cativeiro [PDF]

, 2019
Veronica Oliveira Vianna
openalex   +1 more source

Lymphocyte Micronucleus Formation Is Driven by Inflammation‐Induced Oxidative DNA Damage in Oesophageal Cancer Development

International Journal of Cancer, EarlyView.
Chromosomal instability is a hallmark of cancer, but minimally invasive ways to detect systemic DNA damage and cancer risk remain limited. Here, using patient blood samples, the authors investigated lymphocyte micronuclei (MN) frequency as a potential marker of DNA damage across the progression from gastroesophageal reflux disease to Barrett's ...
Kathryn Munn, Rachel Lawrence, Hasan Haboubi, Hamsa Naser, Kate Hurlow, Ume‐Kulsoom Shah, Lisa Williams, Sarah Gwynne, Owen Bodger, Jiri Zavadil, Francois Virard, Shareen Doak, Laura E. Thomas, Gareth Jenkins   +13 more
wiley   +1 more source