Results 201 to 210 of about 5,415 (251)

2P-FENDO-II: A fiber bundle microscope for all-optical, large field-of-view brain studies in freely moving mice. [PDF]

Cell Rep Methods
Blot FGC, Decombe D, Lorca-Cámara A, Anquetil M, de Sars V, Tourain C, Forget BC, Accanto N, Emiliani V.   +8 more
europepmc   +1 more source

Amylin Receptor Signalling in the Laterodorsal Tegmental Nucleus Controls Food Intake Through Projections to the Ventral Tegmental Area

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background The role of amylin signalling in energy balance control has been understudied in calcitonin receptor (CTR) expressing nuclei such as the mesopontine laterodorsal tegmental nucleus (LDTg). Our lab has shown that LDTg amylin signalling reduces feeding and body weight, but the neuronal phenotype and downstream targets of LDTgCTR cells ...
Marcos J. Sanchez Navarro, Carlie Zhang, Samantha M. Fortin, Matthew R. Hayes   +3 more
wiley   +1 more source

Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs. [PDF]

Anat Rec (Hoboken)
Cornille A, Beguesse K, Wolff E, Zinner C, Asbach P, Clarac F, Witzmann F.   +6 more
europepmc   +1 more source

Microbiome‐mediated immunity: Limited support from the gazelle dung beetle

Ecological Entomology, EarlyView.
Digitonthophagus gazella rely on a maternally inherited microbiome passed across generations via a maternal faecal pellet called the pedestal. We experimentally manipulated the presence of the pedestal, providing it to some individuals while withholding it from others to determine how pedestal microbiota may affect beetle immune potential.
Joshua A. Jones, Irene L. G. Newton, Armin P. Moczek   +2 more
wiley   +1 more source

The effects of cryptic diversity on diversification dynamics analyses in Crocodylia. [PDF]

Proc Biol Sci
Darlim G, Höhna S.
europepmc   +1 more source

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

The FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati, Chandra Sekhar Yadavalli, Md Monirul Hoque, Swapna Thota, Gadiparthi N. Rao   +4 more
wiley   +1 more source

Size, not phylogeny, explains the morphology of the endosseous labyrinth in the crown clade Crocodylia. [PDF]

J Anat
Pochat-Cottilloux Y, Perrichon G, Hautier L, Rinder N, Amiot R, Raselli I, Adrien J, Lachambre J, Fernandez V, Martin JE.   +9 more
europepmc   +1 more source

A live‐cell autophagy reporter reveals reversible vacuolation in naked mole‐rat skin fibroblasts under lysosomal stress

The FEBS Journal, EarlyView.
A tandem fluorescent mCherry–EGFP–LC3 reporter enables live‐cell visualisation of autophagy–lysosome dynamics in naked mole‐rat skin fibroblasts. Chloroquine‐induced lysosomal stress promotes accumulation of neutral LC3‐positive compartments and triggers pronounced LC3‐associated vacuolation.
Fangze Tong, Mateo P. Hoare, Laura J. Grundy, Filomena Gallo, Karin H. Müller, Ewan St. John Smith, Janet R. Kumita   +6 more
wiley   +1 more source

How Happy Do These Animals Look? Exploring Factors Influencing Children's Perceptions of Animal Welfare at the Zoo. [PDF]

Animals (Basel)
Vera-Concha MI, Rojas M, Cartes D, Ceballos MC, Villarroel MC, Pérez M, Venegas V, Briceño C, Calderón-Amor J, Luna D.   +9 more
europepmc   +1 more source

Linoleic Acid Enhances Murine Natural Killer Cell Function In Vitro but Compromises Mitochondrial Bioenergetic Function During Retroviral Infection

Immunology, EarlyView.
Natural Killer (NK) cells are potent effectors against virus‐infected and tumour cells. During Friend Virus (FV) infection, fatty acid metabolism supports NK‐cell effector functions. Here, we found that NK cells from FV‐infected mice preferentially take up linoleic acid (LA), which reduced proliferation, mitochondrial function, and increased reactive ...
Vaasudevan Sridhar, Simone Schimmer, Tanja Werner, Rachel Giesen, Mohamed Saad, Constantin P. Krempe, Sven W. Meckelmann, Ulf Dittmer, Elisabeth Littwitz‐Salomon   +8 more
wiley   +1 more source