Results 131 to 140 of about 2,525 (172)

Low Serum Calcidiol Concentration in Older Adults with Reduced Muscular Function

Journal of the American Geriatrics Society, 1999
OBJECTIVE : To examine the association between muscular function and the serum concentrations of 25‐hydroxyvitamin D (calcidiol) and 1,25‐dihydroxyvitamin D (calcitriol). DESIGN : A randomized population survey.
M Mowé
exaly   +3 more sources

Calcidiol [25(OH)D3]: from diagnostic marker to therapeutical agent

Current Medical Research and Opinion, 2013
Osteoporosis is a skeletal disorder characterized by diminished bone strength, which results in an increased risk of fracture. Currently, osteoporosis is a public health priority due to the large number of individuals affected and the detrimental effect on quality of life.
Salvatore Minisola, Maria Luisa Brandi
exaly   +5 more sources

Effect of Clodronate on Calcidiol Serum Levels in Women with Breast Cancer

Calcified Tissue International, 1997
Maria TERESA Del Campo, Martinez M E, M E Martinez   +2 more
exaly   +3 more sources

Calcidiol and prostate cancer

The Journal of Steroid Biochemistry and Molecular Biology, 2005
Epidemiological studies suggest that serum calcidiol (25(OH)-Vitamin D3) seems to be associated with several cancers including prostate cancer. We have made several experimental studies in order to clarify the mechanism(s) involved in the association.
P, Tuohimaa, O, Golovko, A, Kalueff, N, Nazarova, S, Qiao, H, Syvälä, R, Talonpoika, Y-R, Lou   +7 more
openaire   +2 more sources

A synthesis of 17-epi-calcidiol

Tetrahedron Letters, 2004
Abstract The first synthetic approach to 17- epi -calcidiol 4 and congeners is presented. Key steps of the synthesis involve Pd-catalyzed reaction of the androst-16-ene derivative 6 with alkyl diazoacetates producing the respective cyclopropane derivatives 5 , and lithium in liquid ammonia reduction of 5 leading to 17α-pregnane-20 ...
Alicja Kurek-Tyrlik, Karol Michalak, Zofia Urbanczyk-Lipkowska, Jerzy Wicha   +3 more
openaire   +1 more source

Intraocular calcidiol: Uncovering a role for vitamin D in the eye

The Journal of Steroid Biochemistry and Molecular Biology, 2020
Vitamin D has emerged as a potentially important molecule in ophthalmology. To date, all ophthalmic data pertaining to vitamin D has been restricted primarily to tear and serum analysis in human patients. Considering the isolated nature of the eye, we sought to determine the presence of intraocular vitamin D in ocular disease.25-Hydroxyvitamin D3 (25 ...
Jacob, Rullo, Tracie, Pennimpede, Parsa, Mehraban Far, Yi Ning, Strube, Isabella, Irrcher, Todd, Urton, Mark, Bona, Tom, Gonder, Robert J, Campbell, Martin, Ten Hove, Sanjay, Sharma, James, Farmer, Martin, Petkovich   +12 more
openaire   +2 more sources

Calcidiol and PTH Levels in Women Attending an Osteoporosis Program

Calcified Tissue International, 1999
We performed a retrospective study of 237 patients attending a specialty osteoporosis practice. Secondary causes for reduced bone mineral density (BMD) were evaluated in 196 postmenopausal women and 41 premenopausal women; mean age was 56 +/- 13.8 years (mean +/- SD).
S T, Haden, G E, Fuleihan, J E, Angell, N M, Cotran, M S, LeBoff   +4 more
openaire   +2 more sources

Bone loss after cardiac transplantation: Effects of calcium, calcidiol and monofluorophosphate

Osteoporosis International, 1993
Of 203 patients who underwent cardiac transplantation and were given long-term treatment with cyclosporine and 0.3 mg/kg per day prednisone, 123 were studied prospectively for at least 6 months and 46 for up to 2 years to evaluate the effects on lumbar bone mineral density (BMD) and calcium metabolism of a combined therapy with calcium, calcidiol and ...
E, Meys, F, Terreaux-Duvert, T, Beaume-Six, G, Dureau, P J, Meunier   +4 more
openaire   +2 more sources

Calcitonin, Etidronate, and Calcidiol Treatment in Bone Loss after Cardiac Transplantation

Calcified Tissue International, 1997
Cardiac transplantation is associated with severe bone loss caused by glucocorticoids, immunosuppressive treatment, and other factors. Treatment protocols for the prevention of bone loss is being studied. Forty patients who underwent cardiac transplantation were randomly given calcitonin (n = 13; 100 UI/d, nasal route), etidronate (n = 14; cyclical ...
I, Garcia-Delgado, S, Prieto, L, Gil-Fraguas, E, Robles, J J, Rufilanchas, F, Hawkins   +5 more
openaire   +2 more sources

Interlaboratory Comparison of Calcidiol Determination

1990
Vitamin D must be metabolized before it exerts biological effects. The first step, 25-hydroxylation, is believed to occur mainly in the liver [21]. Subsequently, 25-hydroxyvitamin D (25-OH-D) is further processed in the kidney to 1,25(OH)2D, the biologically most active vitamin D metabolite, or to 24,25(OH)2D [18, 22].
openaire   +1 more source