Effects of Short‐Term Calcifediol Supplementation on Leukocyte Cytokine Production in Healthy Dogs: A Randomized, Double‐Blinded, Placebo‐Controlled Crossover Trial [PDF]
Background Vitamin D modulates the immune response in many species, including dogs. To date, research investigating the immunological effects of vitamin D in dogs is limited to in vitro studies.
Jared A. Jaffey +4 more
doaj +4 more sources
Calcifediol: Why, When, How Much? [PDF]
Vitamin D deficiency is a constantly growing health problem worldwide. Adults affected with hypovitaminosis D could experience negative consequences on their musculoskeletal system and extra-skeletal health.
Teresa Iantomasi +2 more
exaly +7 more sources
Rapid and dose-dependent increase of 25(OH)D levels after calcifediol supplementation in a woman with obesity, chronic liver disease, and osteoporosis [PDF]
VitaminD deficiency is a global concern, and calcifediol serves as an alternative to cholecalciferol for achieving and maintaining optimal vitamin D levels, despite the lack of international guidelines for calcifediol supplementation regimens. We present
Gustavo Kendy Camargo Koga +2 more
doaj +3 more sources
An open-label interventional study on efficacy and safety of 25 µg of daily calcifediol capsule versus 100 µg of cholecalciferol sachets in apparently healthy volunteers [PDF]
Despite the multiple advantages of 25-hydroxyvitamin D (calcifediol or 25(OH)D) compared to cholecalciferol, it is used sparingly. This study was planned to assess the safety and efficacy of supplementing daily 25 µg of calcifediol capsules vis-a-vis 100
Ravi Shah +7 more
doaj +3 more sources
Analysis of the Efficacy and Safety of Weekly Calcifediol 100 µg in Vitamin D Deficient Patients. [PDF]
Background/Objectives: Adequate vitamin D levels are critical for overall health, yet vitamin D deficiency remains prevalent. This study aims to evaluate the efficacy and safety of a standardized weekly supplementation regimen of 100 μg calcifediol for ...
Pérez Castrillón JL +5 more
europepmc +3 more sources
ALBACOVIDIOL Study: Effect of Calcifediol Treatment on Mortality in Patients Hospitalized for COVID-19: A Retrospective Analysis. [PDF]
Background: Immunomodulatory treatments targeting excessive host immune responses favorably shifting the course of COVID-19. High doses of calcifediol may reduce the mortality of this infection.
Blázquez-Cabrera JA +5 more
europepmc +3 more sources
Cholecalciferol vs. calcifediol supplementation on visceral adiposity in people with obesity: a real-world retrospective study [PDF]
IntroductionNowadays it is well known that obesity and vitamin D deficiency are closely linked. In this view, this study aimed to assess the effects of two different Vitamin D formulations, combined with a Mediterranean hypocaloric diet (MHD) on 25(OH)D ...
Martina Chiurazzi +9 more
doaj +3 more sources
Effect of calcifediol and cholecalciferol on muscle function in postmenopausal women: a randomized controlled trial. [PDF]
Brief rationale: Limited evidence exists on calcifediol’s effect on lower extremity function in postmenopausal women with osteoporosis or osteopenia. Main result: Calcifediol (20 µg/day) showed no greater benefit than vitamin D3 (3200 IU/day) or placebo.
Bischoff-Ferrari HA +7 more
europepmc +3 more sources
High-dose extended-release calcifediol successfully treated advanced secondary hyperparathyroidism in an end-stage kidney disease patient: a case report. [PDF]
Hemodialysis (HD) patients lose renal CYP27B1 (cytochrome P450 25-hydroxyvitamin D-1α-hydroxylase) as kidney function declines causing low serum total 25-hydroxyvitamin D (25D) and 1,25-dihydroxyvitamin D (1,25D), and elevated intact parathyroid hormone (
Ashfaq A +5 more
europepmc +2 more sources
Vitamin D3 is the typical vitamin D supplement in aquafeeds, but this form requires further metabolization to the active form. Calcifediol is used in livestock as an alternative, however it isn’t common in aquaculture.
David Dominguez +5 more
doaj +2 more sources

