Results 21 to 30 of about 4,051 (202)

Efficacy of Oral Supplementation with Cholecalciferol Versus Calcifediol in Patients with Hypovitaminosis D After Stroke. [PDF]

open access: yesNutrients
Background/Objectives: Cholecalciferol and Calcifediol are commonly used for oral supplementation in patients with vitamin D deficiency. Several studies have compared these two molecules; however, the studied population has only included healthy ...
Canneva S   +8 more
europepmc   +2 more sources

Vitamin D in the prevention of left ventricular remodelling after an acute myocardial infarction: a randomized clinical trial [PDF]

open access: yesScientific Reports
No clinical trial has yet assessed the effect of vitamin D on patients experiencing ST-segment elevation myocardial infarction (STEMI). In this multicentre, randomised (2:1), double-blind, placebo-controlled trial, 93 patients with anterior STEMI were ...
José Tuñón   +27 more
doaj   +2 more sources

Calcifediol for Use in Treatment of Respiratory Disease

open access: yesNutrients, 2022
Calcifediol is the prohormone of the vitamin D endocrine system (VDES). It requires hydroxylation to move to 1,25(OH)2D3 or calcitriol, the active form that exerts its functions by activating the vitamin D receptor (VDR) that is expressed in many organs, including the lungs. Due to its rapid oral absorption and because it does not require first hepatic
Marta Entrenas-Castillo   +3 more
openaire   +4 more sources

Randomized trial of activated vitamin D for acute kidney injury prevention in critically ill patients [PDF]

open access: yesJCI Insight
BACKGROUND Active vitamin D metabolites, including 25-hydroxyvitamin D (25D) and 1,25-dihydroxyvitamin D (1,25D), have potent immunomodulatory effects that attenuate acute kidney injury (AKI) in animal models.METHODS We conducted a phase 2, randomized ...
David E. Leaf   +11 more
doaj   +2 more sources

Pharmacokinetics of oral vitamin D3 and calcifediol

open access: yesBone, 2014
Long-term pharmacokinetics after supplementation with vitamin D3 or calcifediol (the 25-hydroxyvitamin D3 metabolite) is not well studied. Additionally, it is unclear whether bolus doses of vitamin D3 or calcifediol lead to 25(OH)D3 plasma concentrations considered desirable for fracture prevention (30 ng/mL).
Alexander Jetter   +7 more
openaire   +3 more sources

Ross 708 broiler small intestine morphology and immunity improvements in response to in ovo Marek's Disease vaccine administration alone or in conjunction with in ovo and dietary supplemental calcifediol

open access: yesPoultry Science
: Investigations were performed to determine the systemic immune and small intestine (SI) morphological responses of Ross 708 broilers to the Marek's Disease vaccine (MDV) administered alone or in conjunction with the in ovo and dietary administration of
S.A. Fatemi, A.W. Levy, E.D. Peebles
doaj   +2 more sources

Calcifediol supplementation to reduce pulse pressure in a limited sample of vitamin D deficient older adults with elevated parathyroid hormone levels

open access: yesClinical Nutrition Experimental, 2019
Summary: Vitamin D is proposed as an antihypertensive agent, but current evidence is inconclusive. Calcifediol is more potent in raising vitamin D status.
Pol Grootswagers   +3 more
doaj   +2 more sources

Adjunctive Active Vitamin D Decreases Kidney Function during Treatment of Secondary Hyperparathyroidism with Extended-Release Calcifediol in Non-Dialysis Chronic Kidney Disease in a Randomized Trial.

open access: yesAm J Nephrol
Introduction: Sustained 30% reductions of intact parathyroid hormone (iPTH) with extended-release calcifediol (ERC) are associated with slower decline in estimated glomerular filtration rate (eGFR) in non-dialysis chronic kidney disease (ND-CKD) patients
Ashfaq A   +9 more
europepmc   +2 more sources

Efficacy and Safety of Weekly Calcifediol Formulations (75 and 100 µg) in Subjects with Vitamin D Deficiency: A Phase II/III Randomised Trial. [PDF]

open access: yesNutrients
Background/Objective: Optimal vitamin D levels are required for bone health and proper functionality of the nervous, musculoskeletal and immune systems. The objective of this study was to assess the efficacy and safety profiles of new weekly calcifediol ...
Jódar-Gimeno E   +12 more
europepmc   +2 more sources

Home - About - Disclaimer - Privacy