Effects of Short‐Term Calcifediol Supplementation on Leukocyte Cytokine Production in Healthy Dogs: A Randomized, Double‐Blinded, Placebo‐Controlled Crossover Trial [PDF]
Journal of Veterinary Internal MedicineBackground Vitamin D modulates the immune response in many species, including dogs. To date, research investigating the immunological effects of vitamin D in dogs is limited to in vitro studies.
Jared A. Jaffey +4 more
doaj +4 more sources
European Journal of Nutrition, 2023 Background: In addition to the role of vitamin D in bone mineralization, calcium and phosphate homeostasis, and skeletal health, evidence suggests an association between vitamin D deficiency and a wide range of chronic conditions.
Esteban Jódar +2 more
exaly +3 more sources
ALBACOVIDIOL Study: Effect of Calcifediol Treatment on Mortality in Patients Hospitalized for COVID-19: A Retrospective Analysis. [PDF]
NutrientsBackground: Immunomodulatory treatments targeting excessive host immune responses favorably shifting the course of COVID-19. High doses of calcifediol may reduce the mortality of this infection.
Blázquez-Cabrera JA +5 more
europepmc +3 more sources
Cholecalciferol vs. calcifediol supplementation on visceral adiposity in people with obesity: a real-world retrospective study [PDF]
Frontiers in NutritionIntroductionNowadays it is well known that obesity and vitamin D deficiency are closely linked. In this view, this study aimed to assess the effects of two different Vitamin D formulations, combined with a Mediterranean hypocaloric diet (MHD) on 25(OH)D ...
Martina Chiurazzi +9 more
doaj +3 more sources
npj VaccinesThe ChAdOx1 nCoV-19 (COVISHIELD) vaccine has emerged as a pivotal tool in the global fight against the COVID-19 pandemic. In our previous study eligible subjects were supplemented with calcifediol, a direct precursor to the biologically active form of ...
Himanshu Singh Saroha +6 more
doaj +3 more sources
Synergistic Tuning of Conformational Dynamics, Electron Tunneling, and Substrate Positioning Enhances Electron Transfer in a P450 Chimera for Calcifediol Biosynthesis [PDF]
Advanced ScienceElectron transfer (ET) efficiency dictates catalytic performance in multi‐domain self‐sufficient cytochrome P450s. Conventional engineering, however, predominantly focuses on localized optimization of either the active‐site pocket or linker regions ...
Ziqi Liang +9 more
doaj +3 more sources
Journal of Steroid Biochemistry and Molecular Biology, 2020 OBJECTIVE: The vitamin D endocrine system may have a variety of actions on cells and tissues involved in COVID-19 progression especially by decreasing the Acute Respiratory Distress Syndrome. Calcifediol can rapidly increase serum 25OHD concentration. We
Marta Entrenas Castillo +2 more
exaly +3 more sources
Cholecalciferol or Calcifediol in the Management of Vitamin D Deficiency [PDF]
Nutrients, 2020 Vitamin D deficiency is a global health problem due to its high prevalence and its negative consequences on musculoskeletal and extra-skeletal health. In our comparative review of the two exogenous vitamin D supplementation options most used in our care ...
Manuel Sosa-Henriquez
exaly +8 more sources
Vitamin D Endocrine System and COVID-19: Treatment with Calcifediol [PDF]
Nutrients, 2022 The COVID-19 pandemic is the greatest challenge facing modern medicine and public health systems. The viral evolution of SARS-CoV-2, with the emergence of new variants with in-creased infectious potential, is a cause for concern. In addition, vaccination
JOSÉ Manuel Quesada-Gómez +2 more
exaly +8 more sources
Efficacy of Oral Supplementation with Cholecalciferol Versus Calcifediol in Patients with Hypovitaminosis D After Stroke. [PDF]
NutrientsBackground/Objectives: Cholecalciferol and Calcifediol are commonly used for oral supplementation in patients with vitamin D deficiency. Several studies have compared these two molecules; however, the studied population has only included healthy ...
Canneva S +8 more
europepmc +3 more sources