Calcifediol: Mechanisms of Action
Due to its essential role in calcium and phosphate homeostasis, the secosteroid hormone calcitriol has received growing attention over the last few years. Calcitriol, like other steroid hormones, may function through both genomic and non-genomic mechanisms.
Simone Donati +7 more
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Calcifediol: Why, When, How Much?
Vitamin D deficiency is a constantly growing health problem worldwide. Adults affected with hypovitaminosis D could experience negative consequences on their musculoskeletal system and extra-skeletal health. In fact, an optimal vitamin D status is essential to ensure the correct bone, calcium, and phosphate homeostasis.
Simone Donati +7 more
openaire +4 more sources
Hidroferol 0,266 mg, 10 ampollas bebibles (calcifediol) [PDF]
Abad Santos, Francisco
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A Systematic Review on the Implication of Minerals in the Onset, Severity and Treatment of Periodontal Disease [PDF]
Periodontal disease is an inflammatory disease with high prevalence in adults that leads to destruction of the teeth-supporting tissues. Periodontal therapy has been traditionally directed at reduction of the bacterial load to a level that encourages ...
Battino, Maurizio +4 more
core +5 more sources
Consensus document for the detection and management of chronic kidney disease. [PDF]
Chronic kidney disease (CKD) is a major public health problem that, in its different stages, may affect up to 10% of the Spanish population and results in high morbidity and mortality, as well as high consumption of National Health System resources.
Cebollada, Jesús +19 more
core +1 more source
Calcifediol in patients with hip fractures
Vitamin D deficiency has a high prevalence in the elderly population. This condition can cause sarcopenia and osteoporomalacia, which are associated with an increased risk of falls and fractures, especially of the proximal femur. These fractures have devastating consequences in terms of mortality, disability, and healthcare and social costs ...
Moretti, Antimo +6 more
openaire +1 more source
Genetic Background Can Result in a Marked or Minimal Effect of Gene Knockout (GPR55 and CB2 Receptor) in Experimental Autoimmune Encephalomyelitis Models of Multiple Sclerosis [PDF]
PMCID ...
A Compston +92 more
core +3 more sources
Integral pharmacological management of CKD-MBD II [PDF]
INTRODUCTION: Chronic kidney disease-mineral and bone disorders (CKD-MBD) are associated with costly complications and dismal hard-outcomes. AREAS COVERED: In two comprehensive articles we review contemporary and future pharmacological options for ...
Ballarín, José +9 more
core +2 more sources
Calcifediol for Use in Treatment of Respiratory Disease
Calcifediol is the prohormone of the vitamin D endocrine system (VDES). It requires hydroxylation to move to 1,25(OH)2D3 or calcitriol, the active form that exerts its functions by activating the vitamin D receptor (VDR) that is expressed in many organs, including the lungs. Due to its rapid oral absorption and because it does not require first hepatic
Marta Entrenas-Castillo +3 more
openaire +3 more sources
Diagnosis and management of pseudohypoparathyroidism and related disorders: first international Consensus Statement [PDF]
This Consensus Statement covers recommendations for the diagnosis and management of patients with pseudohypoparathyroidism (PHP) and related disorders, which comprise metabolic disorders characterized by physical findings that variably include short ...
Ahmed, S.F. (Sayed) +45 more
core +2 more sources

