Results 41 to 50 of about 3,013 (168)

Vitamin D supplementation is effective for olanzapine-induced dyslipidemia

Frontiers in Pharmacology, 2023
Olanzapine is an atypical antipsychotic drug that is clinically applied in patients with schizophrenia. It increases the risk of dyslipidemia, a disturbance of lipid metabolic homeostasis, usually characterized by increased low-density lipoprotein (LDL ...
Zijian Zhou, Takuya Nagashima, Takuya Nagashima, Chihiro Toda, Mone Kobayashi, Takahide Suzuki, Kazuki Nagayasu, Hisashi Shirakawa, Satoshi Asai, Shuji Kaneko   +9 more
doaj   +1 more source

Steroid Recognition in Adhesion GPCRs: A Structural and Pharmacological Perspective

Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
ABSTRACT Emerging evidence suggests steroids may act as generalizable ligands for adhesion GPCRs, a receptor class with considerable pharmacological potential. While most studies have focused on the ADGR‘G' subfamily, recent cryo‐EM structures of the androgens 5α‐dihydrotestosterone (5α‐DHT) and methenolone bound to ADGRD1 revealed a putative steroid ...
Bethany Fleming, Abdul‐Akim Guseinov, Irina G. Tikhonova, Graeme Milligan, Nicole A. Perry‐Hauser   +4 more
wiley   +1 more source

Calcifediol boosts efficacy of ChAdOx1 nCoV-19 vaccine by upregulating genes promoting memory T cell responses

npj Vaccines
The ChAdOx1 nCoV-19 (COVISHIELD) vaccine has emerged as a pivotal tool in the global fight against the COVID-19 pandemic. In our previous study eligible subjects were supplemented with calcifediol, a direct precursor to the biologically active form of ...
Himanshu Singh Saroha, Swati Bhat, Liza Das, Pinaki Dutta, Michael F. Holick, Naresh Sachdeva, Raman Kumar Marwaha   +6 more
doaj   +1 more source

Real world evidence of calcifediol or vitamin D prescription and mortality rate of COVID-19 in a retrospective cohort of hospitalized Andalusian patients

Scientific Reports, 2021
COVID-19 is a major worldwide health problem because of acute respiratory distress syndrome, and mortality. Several lines of evidence have suggested a relationship between the vitamin D endocrine system and severity of COVID-19.
Carlos Loucera, María Peña-Chilet, Marina Esteban-Medina, Dolores Muñoyerro-Muñiz, Román Villegas, Jose Lopez-Miranda, Jesus Rodriguez-Baño, Isaac Túnez, Roger Bouillon, Joaquin Dopazo, Jose Manuel Quesada Gomez   +10 more
doaj   +1 more source

Evaluation of Therapies for Secondary Hyperparathyroidism Associated with Vitamin D Insufficiency in Chronic Kidney Disease

Kidney Diseases, 2023
Introduction: Parathyroid hormone-lowering responses after administration of three different therapies capable of raising serum total 25-hydroxyvitamin D (25OHD) were evaluated in patients with secondary hyperparathyroidism (SHPT), vitamin D ...
Stephen A. Strugnell, Philipp Csomor, Akhtar Ashfaq, Charles W. Bishop   +3 more
doaj   +1 more source

Optimizing Muscle Health in Sarcopenia With Dietary Supplements: A Narrative Review

JCSM Communications, Volume 9, Issue 1, January/June 2026.
ABSTRACT Aims Sarcopenia, the age‐related decline in skeletal muscle mass, strength and functionality, significantly contributes to frailty, falls and disability among older adults, resulting in increased morbidity, mortality and healthcare expenditures.
McKenna W. Box, Troy B. Puga, Nathan R. McKenzie, Joseph J. Ruff, Humza Razaq, Lachlan F. Anderson, John T. Riehl   +6 more
wiley   +1 more source

Intersections of vitamin D deficiency, HIV and chronic liver diseases

HIV Medicine, Volume 27, Issue 1, Page 4-17, January 2026.
Abstract Objectives Despite effective antiretroviral therapy (ART), chronic liver diseases remain a leading cause of morbidity and mortality among people with HIV, with metabolic dysfunction–associated steatotic liver disease (MASLD) now the predominant etiology. Vitamin D deficiency is also highly prevalent in this population.
Francesca Farina, Aurgho Datta, Suzanne N. Morin, Sahar Saeed, Bertrand Lebouche, Giovanni Guaraldi, Salvatore Petta, Giada Sebastiani   +7 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

Physiological Basis for Using Vitamin D to Improve Health

Biomedicines, 2023
Vitamin D is essential for life—its sufficiency improves metabolism, hormonal release, immune functions, and maintaining health. Vitamin D deficiency increases the vulnerability and severity of type 2 diabetes, metabolic syndrome, cancer, obesity, and ...
Sunil J. Wimalawansa
doaj   +1 more source

Nutritional Deficiencies Following Bariatric Surgery: A Rapid Systematic Review of Case Reports of Vitamin and Micronutrient Deficiencies Presenting More Than Two Years Post‐Surgery

Clinical Obesity, Volume 15, Issue 6, December 2025.
ABSTRACT Bariatric surgery is the most clinically‐ and cost‐effective intervention for severe obesity. However, without adequate follow‐up, it can lead to nutritional deficiencies. Patients require life‐long nutritional supplements and follow‐up to prevent nutritional deficiencies from developing.
Sophie Haughton, Sarah Gentry, Helen M. Parretti   +2 more
wiley   +1 more source