An open-label interventional study on efficacy and safety of 25 µg of daily calcifediol capsule versus 100 µg of cholecalciferol sachets in apparently healthy volunteers. [PDF]
Despite the multiple advantages of 25-hydroxyvitamin D (calcifediol or 25(OH)D) compared to cholecalciferol, it is used sparingly. This study was planned to assess the safety and efficacy of supplementing daily 25 µg of calcifediol capsules vis-a-vis 100
Shah R +7 more
europepmc +2 more sources
Cholecalciferol (vitamin D3) is an agonist of the Alzheimer's disease–associated immune receptor TREM2 [PDF]
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) is one of the strongest genetic risk factors for late-onset Alzheimer's disease (AD). Several TREM2 ligands are known, including charged lipids and AD-associated proteins like apolipoprotein E and ...
Dean H +10 more
europepmc +2 more sources
This experiment was conducted to determine whether dietary cholecalciferol will alleviate a calcium and phosphorous (CaP) deficiency when one-alpha-hydroxy-cholecalciferol, 1α(OH)D3, is supplemented, and to determine the effects of adequate and ...
Nasir Landy, Majid Toghyani
doaj +3 more sources
Thiamine and Micronutrient Deficiencies in Hospitalized Veterans Without Alcohol Use Disorder. [PDF]
Background: Micronutrient deficiencies (MiDs) can increase medical complexity in hospitalized adults, but the prevalence in those without alcohol use disorder (AUD) is unknown.
Mates EA +4 more
europepmc +2 more sources
Treatment of Hypovitaminosis D With Cholecalciferol in Dogs With Protein-Losing Enteropathies: A Randomized, Double-Blind, Placebo-Controlled, Clinical Trial. [PDF]
Background The effects of vitamin D supplementation are unknown in dogs with protein‐losing enteropathy (PLE). Objective To evaluate the safety, efficacy, and clinical benefit of orally administered cholecalciferol in dogs with PLE and decreased serum ...
Jablonski SA +6 more
europepmc +2 more sources
Oral versus intramuscular cholecalciferol replacement in hemodialysis patients with vitamin D deficiency [PDF]
Introduction: Low 25-hydroxyvitamin D (25(OH)D) level in hemodialysis (HD) patients is associated with high bone turnover, secondary hyperparathyroidism, and decreased bone mineral density (BMD). Objective: To investigate the efficacy of equivalent doses
Maha A. Behairy +5 more
doaj +1 more source
Relation between serum levels of Vitamin D and Immunoglobulin E in Allergic Rhinitis in Upper Egypt
Objective: The object of this study is to evaluate the relation between 25- hydroxy cholecalciferol (vitamin D3) deficiency and allergic rhinitis by detecting level of 25-hydroxy cholecalciferol and Immunoglobulin E serum levels.
Aida A. Abdelmaksoud +3 more
doaj +1 more source
: The objectives of the present study were (1) to evaluate the effect of prepartum cholecalciferol treatment on serum Ca concentration during the first 10 d after calving and (2) to evaluate the effect of treatment on subsequent health and performance ...
P.L. Venjakob +6 more
doaj +1 more source
Review of bioequivalence studies of cholecalciferol drugs [PDF]
Introduction: The general requirements for assessing bioequivalence of endogenous drugs are described in the relevant guidelines, but they do not provide a complete picture of how to adequately develop a design of such a study. The aim of this article is
Alexander L. Khokhlov +1 more
doaj +3 more sources
The aim of this single-center, open-label, randomized controlled study was to evaluate which formulation of vitamin D—between cholecalciferol and calcifediol—is most effective in the treatment of hypovitaminosis D in older adults.
Chukwuma Okoye +9 more
doaj +1 more source

