An open-label interventional study on efficacy and safety of 25 µg of daily calcifediol capsule versus 100 µg of cholecalciferol sachets in apparently healthy volunteers. [PDF]
J Nutr SciDespite the multiple advantages of 25-hydroxyvitamin D (calcifediol or 25(OH)D) compared to cholecalciferol, it is used sparingly. This study was planned to assess the safety and efficacy of supplementing daily 25 µg of calcifediol capsules vis-a-vis 100
Shah R +7 more
europepmc +2 more sources
Animal Nutrition, 2018 This experiment was conducted to determine whether dietary cholecalciferol will alleviate a calcium and phosphorous (CaP) deficiency when one-alpha-hydroxy-cholecalciferol, 1α(OH)D3, is supplemented, and to determine the effects of adequate and ...
Majid Toghyani, Nasir Landy
exaly +3 more sources
Cholecalciferol (vitamin D3) is an agonist of the Alzheimer's disease–associated immune receptor TREM2 [PDF]
NeurotherapeuticsTriggering Receptor Expressed on Myeloid Cells 2 (TREM2) is one of the strongest genetic risk factors for late-onset Alzheimer's disease (AD). Several TREM2 ligands are known, including charged lipids and AD-associated proteins like apolipoprotein E and ...
Dean H +10 more
europepmc +2 more sources
Medicina (Lithuania), 2019 Background and objectives: Vitamin D is an essential vitamin that plays a key role in maintaining physiological calcium balance, and is also a pivotal element in the formation of bone structure.
Sjaak Pouwels, Johannes F Smulders
exaly +3 more sources
Thiamine and Micronutrient Deficiencies in Hospitalized Veterans Without Alcohol Use Disorder. [PDF]
DiseasesBackground: Micronutrient deficiencies (MiDs) can increase medical complexity in hospitalized adults, but the prevalence in those without alcohol use disorder (AUD) is unknown.
Mates EA +4 more
europepmc +2 more sources
Treatment of Hypovitaminosis D With Cholecalciferol in Dogs With Protein-Losing Enteropathies: A Randomized, Double-Blind, Placebo-Controlled, Clinical Trial. [PDF]
J Vet Intern MedBackground The effects of vitamin D supplementation are unknown in dogs with protein‐losing enteropathy (PLE). Objective To evaluate the safety, efficacy, and clinical benefit of orally administered cholecalciferol in dogs with PLE and decreased serum ...
Jablonski SA +6 more
europepmc +2 more sources
Oral versus intramuscular cholecalciferol replacement in hemodialysis patients with vitamin D deficiency [PDF]
Journal of Nephropharmacology, 2022 Introduction: Low 25-hydroxyvitamin D (25(OH)D) level in hemodialysis (HD) patients is associated with high bone turnover, secondary hyperparathyroidism, and decreased bone mineral density (BMD). Objective: To investigate the efficacy of equivalent doses
Maha A. Behairy +5 more
doaj +1 more source
Journal of Dairy Science, 2022 : The objectives of the present study were (1) to evaluate the effect of prepartum cholecalciferol treatment on serum Ca concentration during the first 10 d after calving and (2) to evaluate the effect of treatment on subsequent health and performance ...
P.L. Venjakob +6 more
doaj +1 more source
Relation between serum levels of Vitamin D and Immunoglobulin E in Allergic Rhinitis in Upper Egypt
SVU - International Journal of Medical Sciences, 2021 Objective: The object of this study is to evaluate the relation between 25- hydroxy cholecalciferol (vitamin D3) deficiency and allergic rhinitis by detecting level of 25-hydroxy cholecalciferol and Immunoglobulin E serum levels.
Aida A. Abdelmaksoud +3 more
doaj +1 more source
Review of bioequivalence studies of cholecalciferol drugs [PDF]
Research Results in Pharmacology, 2020 Introduction: The general requirements for assessing bioequivalence of endogenous drugs are described in the relevant guidelines, but they do not provide a complete picture of how to adequately develop a design of such a study. The aim of this article is
Alexander L. Khokhlov +1 more
doaj +3 more sources