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Vitamin D3 and calcidiol are not equipotent
Despite the discussion on the optimal threshold of 25-hydroxyvitamin D serum level continues, there is now consensus on the fact that post-menopausal and elderly populations have inadequate Vitamin D serum levels worldwide. The adjustment of these levels is necessary to improve both bone and general health, as it is to optimize bone response to ...
Navarro-Valverde, Cristina +3 more
openaire +4 more sources
Importance The efficacy of vitamin D3 supplementation in coronavirus disease 2019 (COVID-19) remains unclear. Objective To investigate the effect of a single high dose of vitamin D3 on hospital length of stay in patients with COVID-19.
Igor H. Murai +16 more
semanticscholar +1 more source
Background Two previous meta-analyses showed smaller differences between vitamin D3 and vitamin D2 in raising serum 25-hydroxyvitamin D [25(OH)D] and a consistently high heterogeneity when only including daily dosing studies.
E. G. van den Heuvel +4 more
semanticscholar +1 more source
Objective: Vitamin D deficiency has been associated with an increased risk of COVID-19 severity. This multi-center randomized clinical trial aims to determine the effects of 5000 IU versus 1000 IU daily oral vitamin D3 supplementation in the recovery of ...
Shaun Sabico +11 more
semanticscholar +1 more source
Importance Low levels of 25-hydroxyvitamin D have been associated with higher risk for depression later in life, but there have been few long-term, high-dose large-scale trials.
O. Okereke +12 more
semanticscholar +1 more source
Effect of Vitamin D3 Supplements on Development of Advanced Cancer
Key Points Question Does vitamin D3 supplementation reduce the risk of developing advanced (metastatic or fatal) cancer among adults without a diagnosis of cancer at baseline? Findings In this secondary analysis of a randomized clinical trial with 25 871
P. Chandler +10 more
semanticscholar +1 more source
Importance Severe asthma exacerbations cause significant morbidity and costs. Whether vitamin D3 supplementation reduces severe childhood asthma exacerbations is unclear.
E. Forno +13 more
semanticscholar +1 more source
Microalgae Nannochloropsis oceanica as a future new natural source of vitamin D3.
For the last two decades there has been a rise in awareness about the general low dietary intake of vitamin D3. Fish have the highest natural content of vitamin D3, which is suggested to originate from zooplankton and microalgae.
A. Ljubic +3 more
semanticscholar +1 more source
1alpha,25-Dihydroxyvitamin D3 is a potent suppressor of interferon gamma-mediated macrophage activation. [PDF]
peer reviewed1alpha,25-Dihydroxyvitamin D3 (1alpha,25(OH)2D3), the activated vitamin D3 hormone, is a key regulator of calcium homeostasis and thereby indispensable for bone metabolism.
Bose, Jens +8 more
core +1 more source

