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Vitamin D3 and calcidiol are not equipotent

open access: yesThe Journal of Steroid Biochemistry and Molecular Biology, 2016
Despite the discussion on the optimal threshold of 25-hydroxyvitamin D serum level continues, there is now consensus on the fact that post-menopausal and elderly populations have inadequate Vitamin D serum levels worldwide. The adjustment of these levels is necessary to improve both bone and general health, as it is to optimize bone response to ...
Navarro-Valverde, Cristina   +3 more
openaire   +4 more sources

Vitamin D3 [PDF]

open access: yesSpringer Reference Medizin, 2019
Aryeh Grossman
openaire   +2 more sources

Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2021
Importance The efficacy of vitamin D3 supplementation in coronavirus disease 2019 (COVID-19) remains unclear. Objective To investigate the effect of a single high dose of vitamin D3 on hospital length of stay in patients with COVID-19.
Igor H. Murai   +16 more
semanticscholar   +1 more source

Comparison of the Effect of Daily Vitamin D2 and Vitamin D3 Supplementation on Serum 25-Hydroxyvitamin D Concentration (Total 25(OH)D, 25(OH)D2, and 25(OH)D3) and Importance of Body Mass Index: A Systematic Review and Meta-Analysis

open access: yesAdvances in Nutrition, 2023
Background Two previous meta-analyses showed smaller differences between vitamin D3 and vitamin D2 in raising serum 25-hydroxyvitamin D [25(OH)D] and a consistently high heterogeneity when only including daily dosing studies.
E. G. van den Heuvel   +4 more
semanticscholar   +1 more source

Effects of a 2-Week 5000 IU versus 1000 IU Vitamin D3 Supplementation on Recovery of Symptoms in Patients with Mild to Moderate Covid-19: A Randomized Clinical Trial

open access: yesNutrients, 2021
Objective: Vitamin D deficiency has been associated with an increased risk of COVID-19 severity. This multi-center randomized clinical trial aims to determine the effects of 5000 IU versus 1000 IU daily oral vitamin D3 supplementation in the recovery of ...
Shaun Sabico   +11 more
semanticscholar   +1 more source

Effect of Long-term Vitamin D3 Supplementation vs Placebo on Risk of Depression or Clinically Relevant Depressive Symptoms and on Change in Mood Scores: A Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2020
Importance Low levels of 25-hydroxyvitamin D have been associated with higher risk for depression later in life, but there have been few long-term, high-dose large-scale trials.
O. Okereke   +12 more
semanticscholar   +1 more source

Effect of Vitamin D3 Supplements on Development of Advanced Cancer

open access: yesJAMA Network Open, 2020
Key Points Question Does vitamin D3 supplementation reduce the risk of developing advanced (metastatic or fatal) cancer among adults without a diagnosis of cancer at baseline? Findings In this secondary analysis of a randomized clinical trial with 25 871
P. Chandler   +10 more
semanticscholar   +1 more source

Effect of Vitamin D3 Supplementation on Severe Asthma Exacerbations in Children With Asthma and Low Vitamin D Levels: The VDKA Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2020
Importance Severe asthma exacerbations cause significant morbidity and costs. Whether vitamin D3 supplementation reduces severe childhood asthma exacerbations is unclear.
E. Forno   +13 more
semanticscholar   +1 more source

Microalgae Nannochloropsis oceanica as a future new natural source of vitamin D3.

open access: yesFood Chemistry, 2020
For the last two decades there has been a rise in awareness about the general low dietary intake of vitamin D3. Fish have the highest natural content of vitamin D3, which is suggested to originate from zooplankton and microalgae.
A. Ljubic   +3 more
semanticscholar   +1 more source

1alpha,25-Dihydroxyvitamin D3 is a potent suppressor of interferon gamma-mediated macrophage activation. [PDF]

open access: yes, 2005
peer reviewed1alpha,25-Dihydroxyvitamin D3 (1alpha,25(OH)2D3), the activated vitamin D3 hormone, is a key regulator of calcium homeostasis and thereby indispensable for bone metabolism.
Bose, Jens   +8 more
core   +1 more source

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