Results 31 to 40 of about 786,573 (309)

Vitamin D3 and D3 Metabolites in Young Goats Fed Varying Amounts of Calcium and Vitamin D3

Journal of Dairy Science, 1986
Twenty-four male goats, 2 to 4 wk of age, were allotted to four dietary treatments in a 2 X 2 factorial design and, for 20 wk, were fed a milk diet at 12.5% body weight. Treatments varied in amounts of supplemental calcium and vitamin D3. Daily allowances per kilogram body weight were: 9.4 IU vitamin D3 (basal), 9.4 IU vitamin D3 plus 406 mg calcium ...
T G, Hines, R L, Horst, E T, Littledike, D C, Beitz, N L, Jacobson   +4 more
openaire   +2 more sources

Vitamin D3 an ever green molecule [PDF]

Frontiers in Bioscience, 2013
Vitamin D3 is a key regulator of vertebrates homeostasis. It is synthesized from the precursor 7-dehydrocholesterol upon UVB exposure in the skin and then hydrolyzed in the liver in position 25, to be finally converted into its active form, 1,25-dihydroxyvitamin D (1,25(OH)2D or calcitriol), in the kidneys.
DI ROSA, MICHELINO DANIELE ANTONIO, MALAGUARNERA, Lucia, Nicolosi A, Sanfilippo C, MAZZARINO, Maria Clorinda, Pavone P, Berretta M, Cosentino S, CACOPARDO, Bruno Santi, Pinzone MR, Nunnari G.   +10 more
openaire   +4 more sources

The Vitamin D3 1alpha-Hydroxylase Gene and Its Regulation by Active Vitamin D3 [PDF]

Bioscience, Biotechnology, and Biochemistry, 2011
Vitamin D has a pivotal role in a many biological processes, including the maintenance of calcium homeostasis, cell differentiation and proliferation. Most of these actions are mediated by transcriptional regulation of target genes through vitamin D receptor (VDR), a member the steroid/thyroid hormone receptor superfamily.
TAKEYAMA, Ken-ichi, KATO, Shigeaki
openaire   +2 more sources

1,25(OH)2 vitamin D3, and retinoic acid antagonize endothelin-stimulated hypertrophy of neonatal rat cardiac myocytes.

, 1996
1,25 (OH)(2) Vitamin D-3 (VD3) and retinoic acid (RA) function as ligands for nuclear receptors which regulate transcription, Though the cardiovascular system is not thought to represent a classical target for these ligands, it is clear that both cardiac
Gardner, D. G., J Wu, Garami, Miklós, Cheng, T., T Cheng, Wu, J., M Garami, D G Gardner   +7 more
core   +1 more source

Vitamin D supplementation and breast cancer prevention : a systematic review and meta-analysis of randomized clinical trials [PDF]

, 2013
In recent years, the scientific evidence linking vitamin D status or supplementation to breast cancer has grown notably. To investigate the role of vitamin D supplementation on breast cancer incidence, we conducted a systematic review and meta-analysis ...
Nancy Santesso (435397), Pizzuti, Laura, Pizzuti, L, Montella, Maurizio, Nancy Santesso, Santesso Nancy, Patrizia Vici (85361), Santesso, Nancy, Barba, Maddalena, Anna Crispo (435403), Mariani, Luciano, Barba M., Maugeri-Saccà, Marcello, Maddalena Barba, Montella Maurizio, Laura Pizzuti, Mottolese Marcella, Sergi D., Patrizia Vici, Domenico Sergi, Francesca Sperati, Stranges, Saverio, Luigi Di Lauro (435401), Vici Patrizia, Luciano Mariani (435398), Antonio Giordano, Barba Maddalena, Montella, M, Marcella Mottolese (85368), Sperati, Francesca, Francesca Sperati (95245), Mottolese M., Sperati Francesca, Saverio Stranges, Mariani L., Crispo, A, Di Lauro, L, Laura Pizzuti (435400), Pizzuti L., Saverio Stranges (73786), Marcella Mottolese, Giordano, A, Pizzuti Laura, Crispo A., Marcello Maugeri-Saccà, Barba, M, Maugeri-Saccà Marcello, Stranges, S, Santesso N., Di Lauro, Luigi, Stranges S., Maurizio Montella, Marcello Maugeri-Saccà (435396), Antonio Giordano (55096), Vici P., Sperati, F, Di Lauro Luigi, Sergi, D, Sergi, Domenico, Santesso, N, Mariani, L, Luigi Di Lauro, Giordano, Antonio, MD, Giordano A., Mottolese, M, Giordano, Antonio|, Stranges Saverio, Di Lauro L., Mottolese, Marcella, Maddalena Barba (82927), Sergi Domenico, Crispo Anna, Luciano Mariani, Maurizio Montella (435402), Sperati F., Giordano Antonio, Vici, P, Montella M., Crispo, Anna, Maugeri-Saccà, M, Vici, Patrizia, Mariani Luciano, Anna Crispo, Domenico Sergi (435399), Maugeri-Sacca M.   +84 more
core   +1 more source

Vitamin D3 regulates apoptosis and proliferation in the testis of D-galactose-induced aged rat model

Scientific Reports, 2019
The age-associated imbalances between proliferation and apoptosis lead to impaired spermatogenesis and infertility. The age-associated decline in vitamin D3 levels has been reported and suggested the anti-aging potential of vitamin D3.
M. Jeremy, G. Gurusubramanian, V. Roy
semanticscholar   +1 more source

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

Advanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni, Robin Dolgos, Thomas Menter, Boris Dasen, Arnaud Scherberich, Clémentine Le Magnen, Manuele G. Muraro, Ivan Martin   +7 more
wiley   +1 more source

Pulmonary activation of vitamin D3 and preventive effect against interstitial pneumonia

Journal of clinical biochemistry and nutrition, 2019
Calcitriol [1,25(OH)2D3] is usually investigated in studies on the preventive effect of activated vitamin D against interstitial pneumonia. Although cholecalciferol (vitamin D3) can be easily obtained in the diet and has a longer half-life than ...
I. Tsujino, Ryoko Ushikoshi-Nakayama, T. Yamazaki, N. Matsumoto, I. Saito   +4 more
semanticscholar   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Transposase‐Assisted Donor Tethering Boosts Large‐Fragment HDR in Plants

Advanced Science, EarlyView.
A transposase‐assisted donor tethering strategy is developed to enhance homology‐directed repair in plants. By recruiting donor DNA to double‐strand breaks and synergizing with repair pathway reprogramming and transcription‐coupled donor design, this system markedly improves large‐fragment targeted insertion efficiency, providing a robust platform for ...
Sha Wei, Kai Zhang, Shuke Deng, Jinjie Chen, Xiaomei Huang, Jingfei Guo, Yuqing Wu, Yingjie Guo, Zhen Liang   +8 more
wiley   +1 more source