Results 51 to 60 of about 143,255 (299)

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

Advanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Melissa A. Willman, Alexander Rabassa, Ashley L. Joubert, Tommaso Bo, Letizia Franco, Marzia Conte, Ana L. Anaya‐García, Gabrielle E. Rome, Rim Ouni, Henry J. Seaborne, Camden A. Caffey, Dora M. Berman, Junjun Zheng, Jesus Paez‐Mayorga, Corrine Ying Xuan Chua, Shu Hsia Chen, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

The role of vitamin D3 in follicle development

Journal of Ovarian Research
Vitamin D3 plays a crucial role in female reproduction. As research progresses, the mechanisms of action of vitamin D3 on follicular development have been widely discussed.
Mingxia Li, Shuhui Hu, Jiaxiang Sun, Ying Zhang   +3 more
doaj   +1 more source

Relationship between vitamin D3 level and rheumatoid arthritis patients attending Rizgary Teaching Hospital in Erbil city [PDF]

Zanco Journal of Medical Sciences, 2017
Background and objective: Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology. Vitamin D3 plays an important role in bone metabolism and may also have immunomodulatory effects.
Banaz Abdulsattar Hamad, Shwan K. Media
doaj   +1 more source

Transposase‐Assisted Donor Tethering Boosts Large‐Fragment HDR in Plants

Advanced Science, EarlyView.
A transposase‐assisted donor tethering strategy is developed to enhance homology‐directed repair in plants. By recruiting donor DNA to double‐strand breaks and synergizing with repair pathway reprogramming and transcription‐coupled donor design, this system markedly improves large‐fragment targeted insertion efficiency, providing a robust platform for ...
Sha Wei, Kai Zhang, Shuke Deng, Jinjie Chen, Xiaomei Huang, Jingfei Guo, Yuqing Wu, Yingjie Guo, Zhen Liang   +8 more
wiley   +1 more source

Ameliorative effect of liprotide-encapsulated vitamin D3 on blood glucose, calcium homeostasis, and vitamin D level in a vitamin D and calcium deficient rat model

Frontiers in Nutrition
Vitamin D3, recognized for its higher bioavailability and direct cell utilization, plays a vital role in the human body. Applying β-lactoglobulin with oleic acid (β-Lg-AO) as an encapsulating agent is anticipated to protect and enhance the transport of ...
Gemala Anjani, Reza Achmad Maulana, Sylvia Rahmi Putri, Faizah Fulyani, Ahmad Syauqy, Diana Nur Afifah, Fitriyono Ayustaningwarno, Refani Alycia Kusuma, Zulfatul Masruroh   +8 more
doaj   +1 more source

1(OH) vitamin D3 supplementation improves the sensitivity of the immune-response during Peg-IFN/RBV therapy in chronic hepatitis C patients-case controlled trial. [PDF]

PLoS ONE, 2013
OBJECTIVE: 1,25(OH)2 vitamin D3 can affect immune cells. However, the mechanism responsible for the favorable effects of 1(OH) vitamin D3, which becomes 1,25(OH)2 vitamin D3 in the liver, is not clear.
Yasuteru Kondo, Takanobu Kato, Osamu Kimura, Tomoaki Iwata, Masashi Ninomiya, Eiji Kakazu, Masahito Miura, Takehiro Akahane, Yutaka Miyazaki, Tomoo Kobayashi, Motoyasu Ishii, Norihiro Kisara, Kumiko Sasaki, Haruo Nakayama, Takehiko Igarashi, Noriyuki Obara, Yoshiyuki Ueno, Tatsuki Morosawa, Tooru Shimosegawa   +18 more
doaj   +1 more source

Bone mineral content after renal transplantation [PDF]

, 1984
Forearm bone mineral content (BMC), as evaluated by photonabsorption densitometry, was measured in 28 cadaver kidney donor recipients who entered the study 8 weeks postoperatively and were followed up for 18 months.
A Alvestrand, A Alvestrand, E Ritz, E. Neubauer, E. Ritz, EGA Aird, F Suzuki, HE Nielsen, HK Genant, I Yoshihiro, J Lekkerkerker, JK Davidson, JU Lindgren, K. -H. Krause, K. Dreikorn, KD Tovey, LS Ibels, MG McGeown, N. Neubauer, R Bouillon, R Lindsay, RE Belsey, RG Klein, TJ Hahn, TJ Hahn, TJ Hahn, TJ Hahn, WE Huffer, WSS Jee   +28 more
core   +1 more source

m.10010T>C Mitochondrial Disease: A Case Report With Hypoparathyroidism and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Mitochondria are essential intracellular organelles that play a critical role in cellular metabolism, including the regulation of intracellular calcium signaling. Advances in genomic sequencing have facilitated the identification of rare pathogenic mitochondrial DNA (mtDNA) genetic variants in patients with unexplained endocrine disorders.
Jacob Mohr, Anja Lisbeth Frederiksen, Morten Duno, Anne Pernille Hermann, Trine Maxel Juul, Simone Rask Nielsen   +5 more
wiley   +1 more source

The antibacterial effects of vitamin D3 against mutans streptococci: an in vitro study

European Oral Research, 2021
Purpose This study aims to evaluate the antimicrobial effects of the cholecalciferol vitamin D3 against Streptococcus sobrinus (Strep. sobrinus) and Streptococcus mutans (Strep.
Manal Mohamed Mansour Almoudi, Alaa Sabah Hussein, Mohamed Ibrahim Abu Hassan, Hassanain Al Talib, Hasnah Begum Said Gulam Khan, Siti Arisya Binti Nazli, Nur Aina Efira Binti Effandy   +6 more
doaj   +1 more source

Untangling the Most Probable Role for Vitamin D\u3csub\u3e3\u3c/sub\u3e in Autism [PDF]

, 2017
Recent studies indicate an important role for vitamin D3 in autism spectrum disorder (ASD), although its mechanism is not completely understood.
Godar, Dianne E., Merrill, Stephen J.
core   +1 more source