Results 71 to 80 of about 143,255 (299)

Selective Inhibition of Mammalian DNA Polymerase by Vitamin D2 and D3

Journal of Pharmacological Sciences, 2003
As described previously (H. Togashi et al. Biochem Pharmacol. 1998;56:583–590), the irradiated products of provitamin D2 (ergosterol) inhibit the activities of eukaryotic DNA polymerases.
Yoshiyuki Mizushina, Xianai Xu, Chikako Murakami, Toshio Okano, Masaharu Takemura, Hiromi Yoshida, Kengo Sakaguchi   +6 more
doaj   +1 more source

Non‐classical monocytes frequency and serum vitamin D3 levels are linked to diabetic foot ulcer associated with peripheral artery disease

Journal of Diabetes Investigation, 2023
Aims/Introduction Peripheral artery disease (PAD) serves as a risk factor for diabetic foot ulcers (DFUs). PAD pathology involves atherosclerosis and impaired immunity. Non‐classical monocytes are believed to have an anti‐inflammatory role.
Reham Hammad, Maisa A Abdel Wahab, Nehal Farouk, Mohamed Yahia Zakaria, Mona A Eldosoky, Asmaa A Elmadbouly, Sara A Tahoun, Eman Mahmoud, Seham K Khirala, Amena Rezk Mohammed, Wafaa Abdelaziz Emam, Asmaa A Abo Elqasem, Fatma M Kotb, Rasha Abd Elaziz Abd Elghany   +13 more
doaj   +1 more source

Sex-specific determinants of serum 25-hydroxyvitamin D3 concentrations in an elderly German cohort : a cross-sectional study [PDF]

, 2008
BACKGROUND: Considering the suggested link between vitamin D insufficiency and several chronic diseases, attention should be given to approaches for improving vitamin D status.
Chen, Jinjun, Ren, Kaijun, Song, Junqiang, Xiao, Nong, Zhang, Weimin   +4 more
core   +2 more sources

Comprehensive Characterization of Acer truncatum Leaf Extract: Identification of Systemic Metabolites and Effects on Performance, Antioxidant Status, and Intestinal Microbiota in Laying Hens

Animal Research and One Health, EarlyView.
Dietary A. truncatum leaf extract is absorbed and improves laying performance in aged hens by enhancing systemic antioxidant capacity and modulating the gut microbiota. ABSTRACT The demand for natural feed additives is considerably increasing in the antibiotic‐free feed era.
Kailong Qin, Jiantao Yang, Minglu Gao, Xiaozhao Tao, Xin Yang, Yanli Liu, Xiaojun Yang   +6 more
wiley   +1 more source

Vitamin D3 an ever green molecule [PDF]

Frontiers in Bioscience, 2013
Vitamin D3 is a key regulator of vertebrates homeostasis. It is synthesized from the precursor 7-dehydrocholesterol upon UVB exposure in the skin and then hydrolyzed in the liver in position 25, to be finally converted into its active form, 1,25-dihydroxyvitamin D (1,25(OH)2D or calcitriol), in the kidneys.
DI ROSA, MICHELINO DANIELE ANTONIO, MALAGUARNERA, Lucia, Nicolosi A, Sanfilippo C, MAZZARINO, Maria Clorinda, Pavone P, Berretta M, Cosentino S, CACOPARDO, Bruno Santi, Pinzone MR, Nunnari G.   +10 more
openaire   +4 more sources

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

British Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

The use of vitamin D3 and its metabolites to improve beef tenderness [PDF]

, 2004
Three experiments were conducted to determine whether feeding 25-hydroxyvitamin D3 (25-OH D3) or 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3) improves the tenderness of longissimus dorsi (LD), semimembranosus (SM), and infraspinatus (IF) muscles similar to ...
Beitz, Donald, Foote, Monica, Horst, Ronald, Huff-Lonergan, Elisabeth, Huff-Lonergan, Elisabeth, Parrish, Frederick, Trenkle, Allen   +6 more
core   +2 more sources

Vitamins as potent cancer treatments through regulating the activity and expression of MMP‐2 and MMP‐9

Bulletin of the Korean Chemical Society, EarlyView.
Vitamins could regulate both MMP‐2 and MMP‐9 expression and activity through transcriptional and MAPK signaling pathway modulation. This study highlights the potential of vitamins as low‐toxicity therapeutic or adjunct agents for targeting MMP‐mediated cancer progression. Abstract Matrix metalloproteinases (MMP‐2 and MMP‐9) are key regulators of cancer
Yen Thi Nguyen, Eungchan Kim, Ha Vy Thi Vo, Song Ja Kim, Namdoo Kim, Hyuck Jin Lee   +5 more
wiley   +1 more source

Evaluation of vitamin D3 metabolism in psychiatric disorders

Psychiatry and Clinical Psychopharmacology, 2021
Objective: The detection of vitamin D3 receptors (VDR) in many tissues in the human body has yielded new insights into the mechanism of vitamin D3. As low levels of vitamin D3 were determined in schizophrenia, bipolar disorder, and depression, vitamin ...
Sinan Erenkus, Hakan Balibey, Zehra Erenkus, Onur Durmaz, Recep Tutuncu, Ayhan Algul, Alpay Ates, Servet Ebrinc, Cengiz Basoglu   +8 more
doaj  

Acute effects of Vitamin D3 supplementation on muscle strength in Judoka athletes: a randomized placebo-controlled, double-blind trial [PDF]

, 2015
Objective: Indoor athletes have been shown to be prone to vitamin D3 deficiency. The aim of the study was to examine the acute effects of vitamin D supplementation on muscle function using isokinetic dynamometry.
Cloak, Ross, Gould, Douglas, Ingham, Andrew, Koutedakis, Yiannis, Metsios, George S, Nevill, Alan M, Wolman, Roger, Wyon, Matthew   +7 more
core   +1 more source