Results 61 to 70 of about 65,773 (256)

Improved core manifestations of autism following supplementation with vitamin D3-loaded nanoemulsion

LabMed Discovery
Objective: Children with autism spectrum disorder (ASD) had lower vitamin D3 levels than neurotypical (NT) children, as well as deficits in language, social, and fine motor abilities.
Nagwa A. Meguid, Maha Hemimi, Gina Hussein, Ahmed Elnahry, Marwa Hasanein Asfour, Sameh Hosam Abd El-Alim, Ahmed Alaa Kassem, Abeer Salama, Amr Sobhi Gouda, Walaa Samy Nazim, Radwa Ibrahim Ali Hassan, Neveen Hassan Nashaat   +11 more
doaj   +1 more source

Evaluating Thiram‐Induced Embryotoxicity Using Integrated In Silico, In Vitro, and Transcriptomic Approaches

Environmental Toxicology, EarlyView.
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho, Chun‐Wei Tung, B. Linju Yen, Chen‐Yi Weng, Ju‐Hsin Hsu, Ming‐Hsien Tsai, Salim Arrokhman, Pinpin Lin   +7 more
wiley   +1 more source

Elevated Dietary Vitamin D Supplementation During Winter can Mimic Vitamin D Levels Induced by Summer Daylight Exposure in Atlantic Salmon

Aquaculture Nutrition
Vitamin D3 (cholecalciferol) is an essential nutrient for vertebrate calcium homeostasis, skeletal integrity, and immune function. In aquaculture, declining use of fishmeal and fish oil has reduced dietary vitamin D3 levels in salmon feeds, raising ...
Frederike Keitel-Gröner, David Lausten Knudsen, Eirik Hoel, Margunn Sandstad, Kjetil Berge   +4 more
doaj   +1 more source

Exposure to Structurally Related Organophosphate Esters Elicits Distinct Metabolomic Perturbations in Daphnia magna

Environmental Toxicology, EarlyView.
ABSTRACT Organophosphate esters (OPEs) are found ubiquitously in the environment and exposure to these chemicals has induced behavioral, developmental, and morphological impairments in several model organisms. Yet there is still a lack of understanding of how sub‐lethal exposure disrupts organism function at the molecular‐level, especially for Daphnia ...
Salwa Hajir, Sanam Yousifie, Karl J. Jobst, André J. Simpson, Myrna J. Simpson   +4 more
wiley   +1 more source

Synergy between Vitamin D3 and Toll-Like Receptor Agonists Regulates Human Dendritic Cell Response during Maturation

Clinical and Developmental Immunology, 2013
Human dendritic cells (DC) can be differentiated from blood monocytes in the presence of GM-CSF and IL-4 and matured by lipopolysaccharide (LPS). Vitamin D3 inhibits the maturation of human DC measured by changes in surface expression of HLA-DR, CD14 ...
Anne Brosbøl-Ravnborg, Bettina Bundgaard, Per Höllsberg   +2 more
doaj   +1 more source

Risk factors for dental overgrowth in rabbits: A retrospective study using electronic health records

Veterinary Record, EarlyView.
Abstract Background Rabbits’ teeth grow continuously. Overgrown teeth are a frequent cause for veterinary consultation and can have severe welfare implications. The risk factors for overgrown teeth are incompletely understood. Methods Rabbits with overgrown teeth recorded in their electronic health records (EHRs) were identified from a large population
Mary A. Coles, Alan D. Radford, Melanie Chapman   +2 more
wiley   +1 more source

Real‐World Effectiveness, Treatment Course, and Safety of Tapinarof Cream 1% for Atopic Dermatitis and Plaque Psoriasis in Japan

The Journal of Dermatology, EarlyView.
ABSTRACT Background Tapinarof cream 1%, a non‐steroidal topical aryl hydrocarbon receptor‐modulating agent, is approved in Japan for atopic dermatitis (AD) and plaque psoriasis. Real‐world data on longitudinal outcomes, treatment continuation, interruption and restart, and adverse‐event timing are limited. Methods This single‐center retrospective study
Kanade Iino, Saori Takamura, Tomoo Fukuda   +2 more
wiley   +1 more source

An interplay of light and temperature: Vitamin D3 formation in vitro, a model for in vivo plant studies

Journal of Photochemistry and Photobiology
Vitamin D deficiency is a global issue that requires attention, given its essential functions in the human body. The synthesis of vitamin D3 in the human skin is subject to limitations related to the availability of UV radiation, which can be ...
Maria Fitzner, Natalie Cunningham, Marcel AK Jansen   +2 more
doaj   +1 more source

A new chromatographic system for vitamin D3, and its metabolites: resolution of a new vitamin D3, metabolite

Journal of Lipid Research, 1971
A simple yet powerful new chromatographic procedure for vitamin D3 and its metabolites is described. Liquid–gel partition chromatography on Sephadex LH-20 using a solvent of various percentages of CHCl3 in Skellysolve B (petroleum ether, bp 67–69°C ...
M.F. HOLICK, H.F. DeLUCA
doaj   +1 more source

Beyond thermoregulation: Active behavioural regulation of ultraviolet light exposure by a free‐ranging lizard

Journal of Animal Ecology, EarlyView.
This study provides a clear demonstration of active ultraviolet (UV) regulation in free‐ranging lizards and supports that microhabitat choice likely constrains UV regulation more than thermoregulation. Overall, it serves to establish UV as a parallel regulatory axis of physiological homeostasis and expand the range of testable hypotheses in animal ...
Matthew S. Lattanzio
wiley   +1 more source