Results 61 to 70 of about 786,573 (309)

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

British Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

Função dos hormônios tireoideos e da 1,25(OH)2 vitamina D3 em células testiculares de ratos imaturos [PDF]

, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2015.A espermatogênese, processo que ocorre nos túbulos seminíferos (TS), é controlada por uma rede de fatores ...
Zanatta, Ana Paula
core  

Comparison of the Effect of Daily Versus Bolus Dose Maternal Vitamin D3 Supplementation on the 24,25-dihydroxyvitamin D3 to 25-hydroxyvitamin D3 Ratio

Bone, 2018
Objective Supplementing lactating mothers with high doses of vitamin D3 can adequately meet vitamin D requirements of the breastfed infant. We compared the effect of bolus versus daily vitamin D3 dosing in lactating mothers on vitamin D3 catabolism.
Hemamalini Ketha, T. Thacher, S. Oberhelman, P. Fischer, Ravinder J Singh, R. Kumar   +5 more
semanticscholar   +1 more source

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

British Journal of Clinical Pharmacology, EarlyView.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria, Annisa Lazuardi Larasati, Indri Yuliani Hamdani, Jin‐Gun Cho, Jan‐Willem C. Alffenaar   +4 more
wiley   +1 more source

Vitamin D, innate immunity and outcomes in community acquired pneumonia

, 2011
We investigated the associations between vitamin D status, the antimicrobial peptides cathelicidin and beta defensin-2 and outcomes in community acquired pneumonia.
Karalus, Noel, LEONG LEOW, Cursons, Raymond T., RAY CURSONS, Hancox, Robert J., Leow, Leong, NOEL KARALUS, ROBERT J. HANCOX, TALIA SIMPSON, Leong, Talia   +9 more
core   +1 more source

"Test me and treat me" - attitudes to vitamin D deficiency and supplementation: a qualitative study [PDF]

, 2015
© 2015 BMJ Open, "Test me and treat me"-attitudes to vitamin D deficiency and supplementation: a qualitative study.
Jakeways, Niki; id_orcid, Hull, Sally, Sohanpal, Ratna, Famakin, O, Sohanpal, R, Gadhvi, Dev, Kotta, S, Jakeways, N, Famakin, Olufunke, Martineau, Adrian, Martineau, A, Kotta, Siddharth, Saeed, M, Hull, S, Saeed, Maryum, Griffiths, Chris, Gadhvi, D, Griffiths, C   +17 more
core   +1 more source

Voclosporin‐induced gingival enlargement: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca, Jessica M. Greco, Dimitris N. Tatakis   +2 more
wiley   +1 more source

Proceedings of the Rank Forum on Vitamin D

, 2010
The Rank Forum on Vitamin D was held on 2nd and 3rd July 2009 at the University of Surrey, Guildford, UK. The workshop consisted of a series of scene-setting presentations to address the current issues and challenges concerning vitamin D and health, and ...
Lamberg-Allardt, C, C. Nowson, Martineau, A.R., Miles, LM, Lamberg-Allardt, C., Martineau, AR, Darling, A. L., Macdonald, H M, H. M. Macdonald, Berry, J.L., A. L. Darling, Fraser, WD, S. Reddy, M. Kiely, Darling, A.L., de Groot, CPGM, Macdonald, H. M., C. P. G. M. de Groot, S. A. Lanham-New, Prentice, A., Mavroeidi, A.; id_orcid, de Groot, C P G M, Kiely, M., Stone, E M, Fraser, W. D., Miles, L.M., Macdonald, HM, Lanham-New, S. A., Masud, T, De Groot, C. P.G.M., A. Prentice, Francis, R.M., Vieth, R, Francis, RM, K. D. Cashman, Masud, T., E. Hyppönen, Williams, C. M., Boucher, BJ, de Groot, C.P.G.M., Williams, Christine Mary, Mavroeidi, A., Buttriss, J L, de Groot, C. P. G. M., Boucher, B.J., Mavroeidi, A, Reddy, S., A. Mavroeidi, Nowson, C., Stone, E.M., Cooper, C., W. D. Fraser, Fraser, W D, Cooper, C, A. R. Martineau, Boucher, B. J., Berry, J L, E. M. Stone, Buttriss, J.L., C. Cooper, Francis, R. M., Stone, EM, Williams, CM, Reddy, S, Kiely, K, Kiely, M, Hyppönen, E, T. Masud, Martineau, A. R., Francis, R M, Lanham-New, SA, Vieth, R., C. M. Williams, Hyppönen, E., Prentice, A, Macdonald, H.M., B. J. Boucher, M. Ashwell, Williams, M., J. L. Berry, Ashwell, M., Buttriss, JL, Fraser, W.D., L. M. Miles, Miles, L. M., Nowson, C, Stone, E. M., Cashman, K.D., Lanham-New, S A, C. Lamberg-Allardt, Cashman, K D, Berry, J. L., Berry, J.L, Miles, L M, Cashman, K. D., Ashwell, M, Darling, A L, Buttriss, J. L., J. L. Buttriss, Cashman, KD, de Groot, C.P., R. Vieth, Darling, AL, Williams, C.M., Berry, JL, Lanham-New, S.A., Boucher, B J, Groot, C.P.G.M., de, R. M. Francis, Williams, C M, Martineau, A R, Hypöpnen, E.   +111 more
core   +1 more source

Tuberculosis incidence correlates with sunshine : an ecological 28-year time series study [PDF]

, 2013
Birmingham is the largest UK city after London, and central Birmingham has an annual tuberculosis incidence of 80 per 100,000. We examined seasonality and sunlight as drivers of tuberculosis incidence. Hours of sunshine are seasonal, sunshine exposure is
Martin Dedicoat, Kunst, Heinke, Gavin C K W Koh, Hawthorne Gemma, Koh, Gavin, Hawthorne, Gemma, Koh, Gavin C K W, Turner, AM, Koh, GCKW, Hawthorne, G, Turner, Alice M., Turner Alice M., Alice M Turner, Turner, Alice M, Dedicoat Martin, Dedicoat, Martin, Gemma Hawthorne, Dedicoat, M, Koh Gavin C. K. W., Kunst Heinke, Heinke Kunst, Kunst, H   +21 more
core   +1 more source

Management of severe bone loss in patients at risk of medication‐related osteonecrosis of the jaw with microsurgery and guided bone regeneration: A case study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Medication‐related osteonecrosis of the jaw (MRONJ) is a challenging complication associated with antiresorptive medications. Its exact pathophysiology remains unclear, but dental extractions and infections are known triggers, complicating prevention, and treatment.
Pedro Franco Ferreira, José Maurício Paradella de Camargo, Lara Maria Alencar Ramos Innocentini, Ana Carolina Fragoso Motta   +3 more
wiley   +1 more source