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EFSA JournalEFSA was asked by the European Commission to provide scientific assistance with respect to the EFSA adopted scientific opinion on ‘Safety of calcidiol monohydrate produced by chemical synthesis as a novel food pursuant to Regulation (EU) 2015/2283 ...
Ruth Roldán‐Torres
exaly +5 more sources
Questioning the Safety of Calcidiol in Hemodialysis Patients [PDF]
Nutrients, 2019 Background. Epidemiological studies have suggested a survival benefit for hemodialysis patients on paricalcitol or calcitriol, but nutritional vitamin D supplementation of patients already on vitamin D receptor (VDR) activators is controversial. Methods.
Emilio Gonzalez PARRA +2 more
exaly +3 more sources
Increase in calcidiol level is associated with improved sternal bone healing after cardiac surgery with sternotomy—REINFORCE-D trial results [PDF]
TrialsIntroduction Heart surgery is associated with a sternotomy in most patients. Low serum calcidiol level below 80 nmol/l carries the risk of bone loss as a risk factor in sternotomy healing.
Dalibor Černý +7 more
doaj +2 more sources
Exploring Vitamin D Deficiency and IGF Axis Dynamics in Colorectal Adenomas [PDF]
Biomedicines(1) Colorectal cancer is a major cause of cancer-related death, with colorectal adenomas (CRAs) serving as precursors. Identifying risk factors such as vitamin D deficiency and the insulin-like growth factor (IGF) axis is crucial for prevention. (2) This
George Ciulei +9 more
doaj +2 more sources
Genome-wide association study of blood vitamin D metabolites and bone remodelling markers in pigs [PDF]
BMC GenomicsBackground Bone integrity is crucial for farm animals, particularly pigs, as it has direct impact on animal health and welfare as well as for a sustainable livestock farming.
Dipanwita Paul +4 more
doaj +2 more sources
EFSA Journal, 2023 Following two requests from the European Commission (EC), the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on the revision of the tolerable upper intake level (UL) for vitamin D and to propose a ...
EFSA Panel on Nutrition, Novel Foods and FoodAllergens (NDA) +22 more
exaly +2 more sources
Journal of Immunology Research, 2021 Vitamin D (calcidiol) deficiency in systemic lupus erythematosus (SLE) is more frequent than in healthy subjects (HS); it is associated with clinical activity and damage in SLE.
Mónica R. Meza-Meza +9 more
doaj +1 more source
Coexistence of low vitamin D and high fibroblast growth factor-23 plasma levels predicts an adverse outcome in patients with coronary artery disease. [PDF]
PLoS ONE, 2014 OBJECTIVE: Vitamin D and fibroblast growth factor-23 (FGF-23) are related with cardiovascular disorders. We have investigated the relationship of calcidiol (vitamin D metabolite) and FGF-23 plasma levels with the incidence of adverse outcomes in patients
José Tuñón +15 more
doaj +1 more source
Reduced Hepatic Synthesis of Calcidiol in Uremia [PDF]
Journal of the American Society of Nephrology, 2010 Calcidiol insufficiency is highly prevalent in chronic kidney disease (CKD), but the reasons for this are incompletely understood. CKD associates with a decrease in liver cytochrome P450 (CYP450) enzymes, and specific CYP450 isoforms mediate vitamin D(3) C-25-hydroxylation, which forms calcidiol. Abnormal levels of parathyroid hormone (PTH), which also
Josée, Michaud +8 more
openaire +2 more sources
Vitamin C Deficiency in Blood Samples of COVID-19 Patients
Antioxidants, 2022 Coronavirus disease 2019 (COVID-19) is the most notable pandemic of the modern era. A relationship between ascorbate (vitamin C) and COVID-19 severity is well known, whereas the role of other vitamins is less understood.
Tobias Sinnberg +14 more
doaj +1 more source