Results 31 to 40 of about 3,904 (202)

Calcifediol supplementation in adults on hemodialysis: a randomized controlled trial

Journal of Nephrology, 2021
Background Vitamin D deficiency is associated with increased risks of mortality in people with chronic kidney disease. The benefits and harm of vitamin D supplementation on cardiovascular outcomes and mortality are unknown.
Suetonia C Palmer, Domenico Russo, Loreto Gesualdo   +2 more
exaly   +1 more source

Calcifediol supplementation to reduce pulse pressure in a limited sample of vitamin D deficient older adults with elevated parathyroid hormone levels

Clinical Nutrition Experimental, 2019
Summary: Vitamin D is proposed as an antihypertensive agent, but current evidence is inconclusive. Calcifediol is more potent in raising vitamin D status.
Pol Grootswagers, Anouk M.M. Vaes, Michael Tieland, Lisette C.P.G.M. de Groot   +3 more
doaj   +2 more sources

Calcifediol for Use in Treatment of Respiratory Disease

Nutrients, 2022
Calcifediol is the prohormone of the vitamin D endocrine system (VDES). It requires hydroxylation to move to 1,25(OH)2D3 or calcitriol, the active form that exerts its functions by activating the vitamin D receptor (VDR) that is expressed in many organs,
Marta Entrenas-Castillo, Entrenas-Costa, Luis M., Lourdes Salinero-González, Rubén Andújar-Espinosa, Salinero-González, Lourdes, Entrenas-Castillo, Marta, Entrenas-Costa, Luis M, Andújar-Espinosa, Rubén, Luis M. Entrenas-Costa   +8 more
core   +4 more sources

Pharmacokinetic profile and effect on bone markers and muscle strength of two daily dosage regimens of calcifediol in osteopenic/osteoporotic postmenopausal women [PDF]

Aging Clinical and Experimental Research, 2021
Background: At present, although cholecalciferol represents the form of vitamin D of choice for the treatment of vitamin D deficiency, there is a growing interest in calcifediol.
Stefano Gonnelli, Maria Dea Tomai Pitinca, Silvia Camarri   +2 more
exaly   +2 more sources

Hypovitaminosis D: Is It Time to Consider the Use of Calcifediol?

Nutrients, 2019
Hypovitaminosis D is becoming a notable health problem worldwide. A consensus exists among several different medical societies as to the need for adequate levels of vitamin D for bone and general health.
Roberto Cesareo, Alberto Falchetti, Roberto Attanasio   +2 more
exaly   +2 more sources

Pharmacokinetics of oral vitamin D3 and calcifediol

Bone, 2014
Aim: Long-term pharmacokinetics after supplementation with vitamin D3 or calcifediol (the 25-hydroxyvitamin D3 metabolite) is notwell studied.
Goessl, Richard, Staehelin, H B, Stoecklin, Elisabeth, Dawson-Hughes, Bess, Egli, Andreas, Jetter, Alexander, Bischoff-Ferrari, H A, Henschkowski, Jana   +7 more
core   +3 more sources

Ross 708 broiler small intestine morphology and immunity improvements in response to in ovo Marek's Disease vaccine administration alone or in conjunction with in ovo and dietary supplemental calcifediol

Poultry Science
: Investigations were performed to determine the systemic immune and small intestine (SI) morphological responses of Ross 708 broilers to the Marek's Disease vaccine (MDV) administered alone or in conjunction with the in ovo and dietary administration of
S.A. Fatemi, A.W. Levy, E.D. Peebles
doaj   +2 more sources

Vitamin D and chronic kidney disease: mechanisms, clinical implications, and future perspectives [PDF]

Frontiers in Medicine
BackgroundVitamin D deficiency is common in chronic kidney disease (CKD). Vitamin D/vitamin D receptor (VDR) signaling intersects inflammation, oxidative stress/mitochondrial injury, fibrogenic pathways, the renin–angiotensin–aldosterone system (RAAS ...
Hong Wang, Hong Wang, Hong Wang, Tingting Yuan, Tingting Yuan, Tingting Yuan, Weihua Wu, Weihua Wu, Weihua Wu, Santao Ou, Santao Ou, Santao Ou   +11 more
doaj   +2 more sources

Modified-release oral calcifediol corrects vitamin D insufficiency with minimal CYP24A1 upregulation

Journal of Steroid Biochemistry and Molecular Biology, 2015
Vitamin D insufficiency is prevalent in chronic kidney disease (CKD) and associated with secondary hyperparathyroidism (SHPT) and increased risk of bone and vascular disease.
Martin Petkovich, Charles W Bishop
exaly   +2 more sources

Analysis of the Efficacy and Safety of Weekly Calcifediol 100 µg in Vitamin D Deficient Patients. [PDF]

J Clin Med
Background/Objectives: Adequate vitamin D levels are critical for overall health, yet vitamin D deficiency remains prevalent. This study aims to evaluate the efficacy and safety of a standardized weekly supplementation regimen of 100 μg calcifediol for ...
Pérez Castrillón JL, Jódar-Gimeno E, Molina K, García-Bea A, Ostalé CM, Gilaberte I.   +5 more
europepmc   +2 more sources