Calcifying vascular smooth muscle cells and osteoblasts: Independent cell types exhibiting extracellular matrix and biomineralization-related mimicries [PDF]
, 2014 Background: Ectopic vascular calcifications represent a major clinical problem associated with cardiovascular disease and mortality. However, the mechanisms underlying pathological vascular calcifications are largely unknown hampering the development of ...
Alves, R.D.A.M. (Rodrigo) +3 more
core +1 more source
The role of Matrix Gla Protein in ossification and recovery of the avian growth plate
Frontiers in Endocrinology, 2012 ECM mineralization is an essential physiologic process in bone, teeth, and hypertrophic cartilage. Matrix Gla Protein (MGP), an inhibitor of mineralization, is expressed by chondrocytes and vascular smooth muscle cells to inhibit calcification of those ...
Harel eDan +4 more
doaj +1 more source
Scientific Reports, 2022 Cardiovascular diseases are major causes of death in the western world and this incidence increases in the elderly population. With aging, there are physiologic changes to the cardiac structure secondary to adipose tissue deposition, calcification of ...
Lisa Murphy +4 more
doaj +1 more source
Journal of Oral Research and Review, 2023 Background: Pulp stones (PSs) are calcification within the pulp space formed as a physiologic or pathogenic response. Local and systemic factors are implicated in its occurrence.
Daiasharailang Lyngdoh +4 more
doaj +1 more source
Você conhece esta síndrome? Do you know this syndrome?
Anais Brasileiros de Dermatologia, 2008 A osteodistrofia hereditária de Albright é caracterizada por calcificações cutâneas, obesidade, baixa estatura, braquidactilia associada ao pseudo-hipoparatireoidismo do tipo IA entre outras alterações hormonais como hipotireoidismo e hipogonadismo.
Thais Helena Proença de Freitas +3 more
doaj +1 more source
Evaluation of intracranial physiological calcifications in Computed Tomography
Radiography Open, 2023 Introduction: Intracranial physiological calcifications are not related to any pathological conditions, rather they are due to the normal deposition of calcium or iron in the different parts of the brain. Computed Tomography (CT) scan is superior to all other modalities in terms of sensitivity in the detection of intracranial physiological ...
openaire +2 more sources
ENDOCRINE TUMOURS: Imaging in the follow up of differentiated thyroid cancer: current evidence and future perspectives for a risk-adapted approach [PDF]
, 2016 The clinical and epidemiological profiles of differentiated thyroid cancers (DTCs) have changed in the last three decades. Today's DTCs are more likely to be small, localized, asymptomatic papillary forms.
Deandreis, Désirée +3 more
core +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Dinucleoside polyphosphates : newly detected uraemic compounds with an impact on leucocyte oxidative burst [PDF]
, 2009 Background. Dinucleoside polyphosphates (NpnN) have pathophysiologic roles in cardiovascular disease and are newly detected uraemic retention solutes. They were retrieved in human plasma, tissues and cells.
Dhondt, Annemieke +5 more
core +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source