Calcifying vascular smooth muscle cells and osteoblasts: Independent cell types exhibiting extracellular matrix and biomineralization-related mimicries [PDF]
, 2014 Background: Ectopic vascular calcifications represent a major clinical problem associated with cardiovascular disease and mortality. However, the mechanisms underlying pathological vascular calcifications are largely unknown hampering the development of ...
Alves, R.D.A.M. (Rodrigo) +3 more
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Arterial calcification and bone physiology: role of the bone–vascular axis [PDF]
Nature Reviews Endocrinology, 2012 Bone never forms without vascular interactions. This simple statement of fact does not adequately reflect the physiological and pharmacological implications of the relationship. The vasculature is the conduit for nutrient exchange between bone and the rest of the body.
Bithika, Thompson, Dwight A, Towler
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Vascular Calcification and Stone Disease: A New Look towards the Mechanism
Journal of Cardiovascular Development and Disease, 2015 Calcium phosphate (CaP) crystals are formed in pathological calcification as well as during stone formation. Although there are several theories as to how these crystals can develop through the combined interactions of biochemical and biophysical factors,
Allen J. Yiu +3 more
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The role of Matrix Gla Protein in ossification and recovery of the avian growth plate
Frontiers in Endocrinology, 2012 ECM mineralization is an essential physiologic process in bone, teeth, and hypertrophic cartilage. Matrix Gla Protein (MGP), an inhibitor of mineralization, is expressed by chondrocytes and vascular smooth muscle cells to inhibit calcification of those ...
Harel eDan +4 more
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Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes [PDF]
, 2005 Basic calcium phosphate (BCP) crystals, including hydroxyapatite, octacalcium phosphate (OCP) and carbonate-apatite, have been associated with severe osteoarthritis and several degenerative arthropathies.
Ea, Hang-Korng +3 more
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Scientific Reports, 2022 Cardiovascular diseases are major causes of death in the western world and this incidence increases in the elderly population. With aging, there are physiologic changes to the cardiac structure secondary to adipose tissue deposition, calcification of ...
Lisa Murphy +4 more
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Dinucleoside polyphosphates : newly detected uraemic compounds with an impact on leucocyte oxidative burst [PDF]
, 2009 Background. Dinucleoside polyphosphates (NpnN) have pathophysiologic roles in cardiovascular disease and are newly detected uraemic retention solutes. They were retrieved in human plasma, tissues and cells.
Dhondt, Annemieke +5 more
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Você conhece esta síndrome? Do you know this syndrome?
Anais Brasileiros de Dermatologia, 2008 A osteodistrofia hereditária de Albright é caracterizada por calcificações cutâneas, obesidade, baixa estatura, braquidactilia associada ao pseudo-hipoparatireoidismo do tipo IA entre outras alterações hormonais como hipotireoidismo e hipogonadismo.
Thais Helena Proença de Freitas +3 more
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Journal of Oral Research and Review, 2023 Background: Pulp stones (PSs) are calcification within the pulp space formed as a physiologic or pathogenic response. Local and systemic factors are implicated in its occurrence.
Daiasharailang Lyngdoh +4 more
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Evaluation of intracranial physiological calcifications in Computed Tomography
Radiography Open, 2023 Introduction: Intracranial physiological calcifications are not related to any pathological conditions, rather they are due to the normal deposition of calcium or iron in the different parts of the brain. Computed Tomography (CT) scan is superior to all other modalities in terms of sensitivity in the detection of intracranial physiological ...
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