Results 41 to 50 of about 11,230 (296)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

STUDY OF PHYSIOLOGICAL AND PATHOLOGICAL BREAST CALCIFICATIONS ON MAMMOGRAPHY

Journal of Evolution of Medical and Dental sciences, 2013
INTRODUCTION: Breast calcifications are too small to feel. They can be seen on mammography. They are common and found in about half of all mammograms of females aged 50 and older and one in 10 mammograms of young women. The initial assessment of calcification is made to determine if they confirm well established benign morphologies. Calcifications with
Sonia Baweja, Saurabh Baweja, Asha Dixit, Abhijeet Yadav, Monika Shrivastava   +4 more
openaire   +1 more source

Physiologic intracranial calcifications incidentally detected on cone beam computed tomography

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2022
This study aims to determine the incidence of physiologic intracranial calcifications on cone beam computed tomography (CBCT) and to contribute to the differentiation between physiologic and pathologic intracranial calcifications by sharing their characteristic appearances, with the largest number of patients in the literature and many different types ...
Rabia Duman Tepe, Hulya Cakir Karabas, Ahmet Faruk Erturk, Ilknur Ozcan   +3 more
openaire   +3 more sources

Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD

, 2004
Patients with ESRD have a high circulating calcium (Ca) x phosphate (P) product and develop extensive vascular calcification that may contribute to their high cardiovascular morbidity. However, the cellular mechanisms underlying vascular calcification in
Jahnen-Dechent, W, Willi Jahnen-Dechent, Jeremy N. Skepper, Diane Proudfoot, Joannides, Alexis J., Alexis J. Joannides, Reynolds, Joanne L., Proudfoot, Diane, Joanne L. Reynolds, Joannides, AJ, Shanahan, Catherine M., Skepper, JN, Rosamund McNair, Weissberg, Peter L., Reynolds, JL, Proudfoot, D, Catherine M. Shanahan, Schurgers, LJ, Skepper, Jeremy N., Shanahan, CM; id_orcid, Weissberg, PL, Leon J. Schurgers, Peter L. Weissberg, Schurgers, Leon J., Jahnen-Dechent, Wilhelm, McNair, R, McNair, Rosamund   +26 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Cone Beam Computed Tomographic Evaluation of Intracranial Physiologic Calcifications

Journal of Craniofacial Surgery, 2019
Objective: The aim of the present study was to evaluate the incidence of physiologic intracranial calcifications detected in cone beam computed tomography (CBCT) images of a Turkish subpopulation. Methods: The CBCT image of the full head of 573 patients taken between 2015 and 2018 ...
Bayrak, Seval, Bulut, Duygu Göller, Çakmak, Emine Şebnem Kurşun, Orhan, Kaan   +3 more
openaire   +4 more sources

Lung to finger circulation time in sleep study and coronary artery calcification: the Multi-Ethnic Study of Atherosclerosis

, 2020
Lung to finger circulation time (LFCT) measured from sleep studies may represent a novel physiologic marker for cardiovascular risk in patients with sleep disordered breathing (SDB).
Jacobs, David, Reid, Michelle, Punjabi, Naresh, Redline, Susan, Mariani, Sara, Lima, Joao, Kapur, Vishesh, Kwon, Younghoon   +7 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Case report: extreme coronary calcifications and hypomagnesemia in a patient with a 17q12 deletion involving HNF1B

BMC Nephrology, 2019
Background 17q12 deletion syndrome encompasses a broad constellation of clinical phenotypes, including renal magnesium wasting, maturity-onset diabetes of the young (MODY), renal cysts, genitourinary malformations, and neuropsychiatric illness ...
Howard J. Li, Catherine Groden, Melanie P. Hoenig, Evan C. Ray, Carlos R. Ferreira, Willam Gahl, Danica Novacic   +6 more
doaj   +1 more source