Results 181 to 190 of about 508,286 (387)

Self‐Cascade Catalytic Reaction–Assisted Apoptosis/Calcicoptosis/Ferroptosis Induction with Microsphere‐Aggregated Hydrogels in Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
Hyaluronic acid‐dopamine‐based intra‐crosslinked microsphere including cisplatin (HPC MS) is fabricated by spray‐drying and calcium/iron ions are introduced for interparticle crosslinking. Designed microsphere‐aggregated hydrogel (MAH) system including cisplatin/CaO2/FeSO4 can provide apoptosis/calcicoptosis/ferroptosis‐mediated chemo/cascade ...
ChaeRim Hwang   +6 more
wiley   +1 more source

Sodium-glucose cotransporter 2 inhibitors attenuate vascular calcification by suppressing endoplasmic reticulum protein thioredoxin domain containing 5 dependent osteogenic reprogramming

open access: yesRedox Biology
Aims: Vascular calcification is strongly linked to the development of major adverse cardiovascular events, but effective treatments are lacking. Sodium-glucose cotransporter 2 (SGLT2) inhibitors are an emerging category of oral hypoglycemic drugs that ...
Shaofa Wu   +12 more
doaj  

Calcific uraemic arteriolopathy - A mini-review [PDF]

open access: yes, 2016
Calcific Uraemic Arteriolopathy (CUA) or calciphylaxis, is a thrombotic disorder of skin and subcutaneous tissue which typically presents with painful purpuric nodules that may progress to necrotic ulcers, and is a severe, life-threatening condition. CUA
Agapii, Rodica   +7 more
core  

Advanced Micro‐OLED Integration on Thin and Flexible Polymer Neural Probes for Targeted Optogenetic Stimulation

open access: yesAdvanced Functional Materials, EarlyView.
This paper introduces a flexible neural probe with integrated micro‐OLEDs on a flexible substrate for the first time, featuring 8 micro‐OLEDs and recording electrodes for optogenetics. It uses advanced encapsulation and an IAI anode for durability, emitting 470 nm light for ChR2 activation, enabling high‐resolution, minimally invasive stimulation ...
Somin Lee   +8 more
wiley   +1 more source

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy