Results 11 to 20 of about 33,094 (317)

Calcinosis Cutis and Calciphylaxis in Autoimmune Connective Tissue Diseases

Vaccines, 2023
Calcinosis represents a severe complication of several autoimmune disorders. Soft-tissue calcifications have been classified into five major types: dystrophic, metastatic, idiopathic, iatrogenic, and calciphylaxis.
Ilaria Mormile, Francesca Mosella, Piergiorgio Turco, Filomena Napolitano, Amato de Paulis, Francesca Wanda Rossi   +5 more
doaj   +2 more sources

Autoimmune hyperphosphatemic tumoral calcinosis in a patient with FGF23 autoantibodies [PDF]

Journal of Clinical Investigation, 2018
Hyperphosphatemic familial tumoral calcinosis (HFTC)/hyperostosis-hyperphosphatemia syndrome (HHS) is an autosomal recessive disorder of ectopic calcification due to deficiency of or resistance to intact fibroblast growth factor 23 (iFGF23). Inactivating
Burbelo, Christopher J. Romero, Daniela Egli-Spichtig, Emily Farrow, Farzana Perwad, Ichikawa, Lori C. Guthrie, Mary Scott Roberts, Michael J. Econs, Michael T. Collins, Peter D. Burbelo, Rachel I. Gafni, Shimada, Shoji Ichikawa, Uchida   +14 more
core   +2 more sources

Assessment, classification and treatment of calcinosis as a complication of juvenile dermatomyositis: a survey of pediatric rheumatologists by the childhood arthritis and rheumatology research alliance (CARRA)

Pediatric Rheumatology Online Journal, 2017
Background There is no standardized approach to the management of JDM-associated calcinosis and its phenotypes. Current knowledge of treatment outcomes is confined to small series and case reports.
A. B. Orandi, K. W. Baszis, V. R. Dharnidharka, A. M. Huber, M. F. Hoeltzel, for the CARRA Juvenile Myositis subgroup   +5 more
doaj   +2 more sources

Management of Calcinosis Cutis in Rheumatic Diseases

Journal of Rheumatology, 2022
Calcinosis (hydroxyapatite and calcium phosphate crystal deposition) within the extracellular matrix of the dermis and subcutaneous tissue is a frequent manifestation of adult and pediatric systemic autoimmune rheumatic diseases, specifically systemic ...
Hadiya Elahmar, B. Feldman, S. Johnson
semanticscholar   +1 more source

Development of a computed tomography calcium scoring technique for assessing calcinosis distribution, pattern and burden in dermatomyositis.

Rheumatology, 2023
OBJECTIVES To utilize whole-body computed tomography (CT) imaging and calcium scoring techniques as tools for calcinosis assessment in a prospective cohort of patients with adult and juvenile dermatomyositis (DM and JDM, respectively).
Briana A Cervantes, Prateek C. Gowda, L. Rider, F. Miller, Marcus Y. Chen, Adam Schiffenbauer   +5 more
semanticscholar   +1 more source

CREST Syndrome in Systemic Sclerosis Patients – Is Dystrophic Calcinosis a Key Element to a Positive Diagnosis?

Journal of Inflammation Research, 2022
Introduction CREST syndrome is a clinical entity associated with systemic sclerosis, which meets at least three of the five clinical features: calcinosis, Raynaud’s phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.
Carmen Bobeica, E. Niculeț, Mihaela Craescu, Elena-Laura Parapiru, C. Musat, C. Dinu, Iulia Chiscop, L. Nechita, M. Debita, V. Stefanescu, I. Stefanopol, Alexandru Nechifor, A. Pelin, Gabriela Bălan, Silvia Chirobocea, C. Vasile, A. Tatu   +16 more
semanticscholar   +1 more source

Cumulative Disease Damage and Anti-PM/Scl Antibodies Are Associated with a Heavy Burden of Calcinosis in Systemic Sclerosis.

Rheumatology, 2022
OBJECTIVES Ectopic calcification (calcinosis) is a common complication of systemic sclerosis, but a subset of systemic sclerosis patients has a heavy burden of calcinosis. We examined whether there are unique risk factors for a heavy burden of calcinosis,
Carrie Richardson, J. Perin, S. Zeger, F. Wigley, L. Hummers, L. Casciola-Rosen, A. Rosen, Ami A. Shah   +7 more
semanticscholar   +1 more source

Local, non-systemic, and minimally invasive therapies for calcinosis cutis: a systematic review

Archives of Dermatological Research, 2021
Calcinosis cutis is a deposition of calcium in the skin and subcutaneous tissue, often accompanied by pain, reduced mobility, and chronic infections. Limited evidence is available about the feasibility and efficacy of therapies alternative to systemic ...
Joanna Nowaczyk, Michał Zawistowski, P. Fiedor   +2 more
semanticscholar   +1 more source

Bisphosphonates for the Treatment of Calcinosis Cutis—A Retrospective Single-Center Study

Biomedicines, 2021
(1) Background: Calcinosis cutis is a frequent symptom of autoimmune connective tissue diseases leading to pain, transcutaneous expulsion of calcified material and bacterial superinfection.
Lilian Rauch, R. Hein, T. Biedermann, K. Eyerich, F. Lauffer   +4 more
semanticscholar   +1 more source

Subcutaneous calcinosis: Is it different between systemic sclerosis and dermatomyositis?

Journal of Scleroderma and Related Disorders, 2021
Calcinosis cutis is the deposition of insoluble calcium in the skin and subcutaneous tissues. It is a manifestation of several autoimmune connective tissue diseases, most frequently with systemic sclerosis and juvenile dermatomyositis, followed by adult ...
A. Valenzuela, L. Chung
semanticscholar   +1 more source