Results 11 to 20 of about 32,489 (314)

Is Anti-NXP2 Autoantibody a Risk Factor for Calcinosis and Poor Outcome in Juvenile Dermatomyositis Patients? Case Series

Frontiers in Pediatrics, 2022
Juvenile dermatomyositis (JDM) has a wide spectrum of clinical presentations. In the last decade, several myositis-specific antibodies have been identified in patients with JDM and connected with specific organ involvement or specific clinical picture ...
Natasa Toplak, Pallavi Pimpale Chavan, Silvia Rosina, Tomas Dallos, Oz Rotem Semo, Cassyanne L. Aguiar, Raju Khubchandani, Angelo Ravelli, Angelo Ravelli, Anjali Patwardhan   +9 more
doaj   +2 more sources

Calcinosis in juvenile dermatomyositis: Updates on pathogenesis and treatment

Frontiers in Medicine, 2023
Calcinosis, or the deposition of insoluble calcium salts in the skin, subcutaneous tissue, fascia, tendons, and muscles, is a feared complication of juvenile dermatomyositis.
Caitlan S. Pinotti, Laura Cannon, Jeffrey A. Dvergsten, Eveline Y. Wu, Eveline Y. Wu   +4 more
doaj   +2 more sources

Calcinosis Cutis and Calciphylaxis in Autoimmune Connective Tissue Diseases

Vaccines, 2023
Calcinosis represents a severe complication of several autoimmune disorders. Soft-tissue calcifications have been classified into five major types: dystrophic, metastatic, idiopathic, iatrogenic, and calciphylaxis.
Ilaria Mormile, Francesca Mosella, Piergiorgio Turco, Filomena Napolitano, Amato de Paulis, Francesca Wanda Rossi   +5 more
doaj   +2 more sources

Osteoclastogenesis in Patients With Systemic Sclerosis With and Without Calcinosis Cutis [PDF]

ACR Open Rheumatology
Objective We aimed to assess whether the presence of radiographically confirmed calcinosis of the hands in patients with systemic sclerosis (SSc) is associated with increased osteoclastogenesis.
Antonia Valenzuela, Guillermo Pérez, Lorinda Chung, Felipe Sánchez, Carolina Iturriaga, Rebeca Montalva, Arturo Borzutzky   +6 more
doaj   +2 more sources

Autoimmune hyperphosphatemic tumoral calcinosis in a patient with FGF23 autoantibodies [PDF]

Journal of Clinical Investigation, 2018
Hyperphosphatemic familial tumoral calcinosis (HFTC)/hyperostosis-hyperphosphatemia syndrome (HHS) is an autosomal recessive disorder of ectopic calcification due to deficiency of or resistance to intact fibroblast growth factor 23 (iFGF23). Inactivating
Burbelo, Christopher J. Romero, Daniela Egli-Spichtig, Emily Farrow, Farzana Perwad, Ichikawa, Lori C. Guthrie, Mary Scott Roberts, Michael J. Econs, Michael T. Collins, Peter D. Burbelo, Rachel I. Gafni, Shimada, Shoji Ichikawa, Uchida   +14 more
core   +2 more sources

Hyperphosphatemic Tumoral Calcinosis: Pathogenesis, Clinical Presentation, and Challenges in Management

Frontiers in Endocrinology, 2020
Hyperphosphatemic familial tumoral calcinosis (HFTC) is a rare and disabling disorder of fibroblast growth factor 23 (FGF23) deficiency or resistance.
Rachel I Gafni
exaly   +2 more sources

Clinical phenotypes and biologic treatment use in juvenile dermatomyositis-associated calcinosis [PDF]

Pediatric Rheumatology Online Journal, 2018
Background Few risk factors have been identified for the development of calcinosis among patients with Juvenile Dermatomyositis, and currently no clinical phenotype has been associated with its development.
Al-Hammadi, Noor, Baszis, Kevin W, CARRA Legacy Registry Investigators,, Dharnidharka, Vikas R, Orandi, Amir B   +4 more
core   +3 more sources

Outcome Measures in Dystrophic Calcinosis Cutis: A Systematic Review [PDF]

JID Innovations
Background: Calcinosis cutis is a skin condition characterized by calcium salt deposition in the skin and subcutaneous tissues, significantly affecting patients' QOL.
Jennifer Foster, Leslie Guerrero, Benjamin F. Chong   +2 more
doaj   +2 more sources

Clinical course and potential associated factors of progressive calcinosis cutis in early systemic sclerosis: a cohort study [PDF]

Annals of Medicine
Background Calcinosis cutis of hands can progress and impair hand function in systemic sclerosis (SSc). Understanding the natural disease and comprehensive management is crucial.Objective To examine clinical course and identify risk factors associated ...
Vassana Kanjanajarurat, Prathana Chowchuen, Chingching Foocharoen, Punthip Thammaroj   +3 more
doaj   +2 more sources

Calcinosis in Scleroderma [PDF]

Proceedings of the Royal Society of Medicine, 1976
J N Rosenberg, Jayne Lewis
openalex   +4 more sources