Results 61 to 70 of about 25,410 (271)

Dermatomyositis and Breast Calcinosis [PDF]

, 1999
The authors report a rare case of dermatomyositis diagnosed at the Mastology Sector of the Division of Gynecology of the Federal University of São Paulo - Escola Paulista de Medicina, which caused breast deformity due to formation of bilateral dystrophic
Bernardes Jr., Júlio Roberto De M., Facina, Gil, Gebrim, Luiz Henrique, Kemp, Claudio, Lima, Geraldo Rodrigues De, Nazário, Afonso Celso Pinto   +5 more
core   +3 more sources

Lysophosphatidic Acid Synergizes With 1,25‐Dihydroxyvitamin D to Promote Fibroblast Growth Factor‐23 Synthesis via MAPK Signaling and Induction of the IL12A Gene

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Ay et al. investigated the cellular mechanisms behind the role of lysophosphatidic acid (LPA) in FGF23 production. They revealed that LPA cooperates with 1,25‐dihydroxyvitamin D (1,25D), that is, the bioactive form of vitamin D known to stimulate FGF23 synthesis. This synergy entails MAPK signaling and the induction of the gene encoding the interleukin‐
Birol Ay, Sajin Marcus Cyr, Yorihiro Iwasaki, Elizabeth Hill, Eugene P. Rhee, Nevil J. Singh, Petra Simic, Murat Bastepe   +7 more
wiley   +1 more source

Calcinosis in systemic sclerosis: prevalence, clinical picture, management, complications

Bolʹ, Sustavy, Pozvonočnik, 2019
This literature review summarizes current data on the epi­demiology, pathophysiology, diagnosis and treatment of calcinosis cutis in patients with systemic sclerosis (SSc).
Ye.D. Yehudina, I.Yu. Golovach
doaj   +1 more source

Conditional Deletion of Murine Fgf23: Interruption of the Normal Skeletal Responses to Phosphate Challenge and Rescue of Genetic Hypophosphatemia [PDF]

, 2016
The transgenic and knockout (KO) animals involving Fgf23 have been highly informative in defining novel aspects of mineral metabolism, but are limited by shortened lifespan, inability of spatial/temporal FGF23 control, and infertility of the global KO ...
Allen, Matthew R., Bellido, Teresita, Cass, Taryn A., Clinkenbeard, Erica L., Hum, Julia M., Ni, Pu, White, Kenneth E.   +6 more
core   +1 more source

Prevalence and Clinical Characteristics of Systemic Sclerosis in Alaska Native and American Indian Peoples in Alaska

ACR Open Rheumatology, Volume 8, Issue 1, January 2026.
Objective Systemic sclerosis (SSc) is known to exhibit significant epidemiologic and clinical variation. This study aimed to describe the clinical and epidemiologic characteristics of SSc in Alaska Native and American Indian (AN/AI) individuals in Alaska.
Vivek R. Mehta, Peter Holck, Tammy L. Choromanski, Amy Wilson, Flora Lee, Elizabeth D. Ferucci   +5 more
wiley   +1 more source

Assessment, classification and treatment of calcinosis as a complication of juvenile dermatomyositis: a survey of pediatric rheumatologists by the childhood arthritis and rheumatology research alliance (CARRA)

Pediatric Rheumatology Online Journal, 2017
Background There is no standardized approach to the management of JDM-associated calcinosis and its phenotypes. Current knowledge of treatment outcomes is confined to small series and case reports.
A. B. Orandi, K. W. Baszis, V. R. Dharnidharka, A. M. Huber, M. F. Hoeltzel, for the CARRA Juvenile Myositis subgroup   +5 more
doaj   +1 more source

Abatacept in the Treatment of Juvenile Dermatomyositis-Associated Calcifications in a 16-Year-Old Girl

Case Reports in Rheumatology, 2020
Calcinosis is a feared complication of JDM that may be seen in up to 40% of children with JDM. It is associated with negative impact on the patients’ quality of life due to weakness, functional disability, joint contractures, muscle atrophy, skin ulcers,
Sukesh Sukumaran, Vini Vijayan
doaj   +1 more source

Incidental Diagnosis of Fahr's Disease Following Severe Traumatic Brain Injury: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Fahr's disease is a rare idiopathic neurodegenerative disorder characterized by symmetrical calcifications in the basal ganglia and cerebellar dentate nuclei. Although it may present with diverse neuropsychiatric symptoms, a significant number of cases remain asymptomatic and are only identified incidentally through neuroimaging performed for ...
Hadi Ebrahimi, Ali Holakoo, Seyyed Ebrahim Hejazian, Hamed Ahmadian, Amir Hosein Zohrevand, Morteza Sharifzadeh   +5 more
wiley   +1 more source

Comparison of the Utility and Validity of Three Scoring Tools to Measure Skin Involvement in Patients With Juvenile Dermatomyositis [PDF]

, 2016
OBJECTIVE: To compare the abbreviated Cutaneous Assessment Tool (CAT), Disease Activity Score (DAS), and Myositis Intention to Treat Activity Index (MITAX) and correlate them with the physician's 10-cm skin visual analog scale (VAS) in order to define ...
Almeida, B, Arnold, K, Campanilho-Marques, R, de Iorio, M, Deakin, C, Gallot, N, Juvenile Dermatomyositis Research Group, ., Nistala, K, Pilkington, CA, Wedderburn, LR   +9 more
core   +1 more source

Clinical course and potential associated factors of progressive calcinosis cutis in early systemic sclerosis: a cohort study

Annals of Medicine
Background Calcinosis cutis of hands can progress and impair hand function in systemic sclerosis (SSc). Understanding the natural disease and comprehensive management is crucial.Objective To examine clinical course and identify risk factors associated ...
Vassana Kanjanajarurat, Prathana Chowchuen, Chingching Foocharoen, Punthip Thammaroj   +3 more
doaj   +1 more source