Results 301 to 310 of about 152,832 (396)

Toward Novel Targeted Therapy for Overactive Bladder: A Cadaver Study Identifying Critical Autonomic Nerve Structures

Neurourology and Urodynamics, Volume 44, Issue 8, Page 1695-1703, November 2025.
ABSTRACT Introduction and Objectives Targeted radiofrequency (RF) therapy is a promising treatment for overactive bladder (OAB), aiming to modulate autonomic nerve pathways for symptom control. This cadaveric study focuses on identifying areas of high nerve density in the bladder and corresponding vaginal wall (AVW) to support RF use in a minimally ...
Gamal Ghoniem, Mickey Karram, Muhammed A. M. Hammad   +2 more
wiley   +1 more source

<i>CYP24A1</i> loss-of-function mutation as a rare cause of parathyroid (PTH)-independent severe hypercalcaemia in pregnancy. [PDF]

Obstet Med
Morton A.
europepmc   +1 more source

Acute Chemodenervation of the Bladder With Botulinum Toxin After Spinal Cord Injury Resulted in Preserved Bladder Function in Rodents

Neurourology and Urodynamics, Volume 44, Issue 8, Page 1704-1712, November 2025.
ABSTRACT Despite modern bladder management methods, lower and upper urinary tract complications still contribute significantly to morbidity and diminished quality of life in persons with spinal cord injuries (SCI). Neurogenic overactive bladders often develop after SCI and this can result in loss of compliance, with concomitant urinary tract ...
Noor Al‐Khayat, Lindsay N. Cates, Benjamin R. Valenti, Mark P. Hudson, Claire C. Yang, Zin Z. Khaing   +5 more
wiley   +1 more source

Impact of anti-CGRP monoclonal antibodies on treatment satisfaction and quality of life in patients with resistant migraine: a retrospective real-world study. [PDF]

BMC Neurol
Cardona-Roca L, Seguí-Solanes C, Cano-Alonso M, Sosa-Pons A, Almendros-Abad N, Sola NR.   +5 more
europepmc   +1 more source

Structural similarities reveal an expansive conotoxin family with a two‐finger toxin fold

Protein Science, Volume 34, Issue 11, November 2025.
Abstract Venomous animals have evolved a diverse repertoire of toxins with considerable pharmaceutical potential. The rapid evolution of peptide toxins, such as the conotoxins produced by venomous marine cone snails, often complicates efforts to infer their evolutionary relationships based solely on sequence information.
Muhammad Saad Khilji, Celeste M. Hackney, Thomas L. Koch, Arik J. Hone, Aymeric Rogalski, Maren Watkins, Jortan Tun, J. Michael McIntosh, Baldomero Olivera, Helena Safavi‐Hemami, Kaare Teilum, Lars Ellgaard   +11 more
wiley   +1 more source

A Comparative Study on the Multidimensional Features of Hereditary and Sporadic Medullary Thyroid Carcinoma Patients: A Single-Center Retrospective Study. [PDF]

Medicina (Kaunas)
Deniz MS, Nasiroglu Imga N, Tural Balsak BO, Safak Bulut A, Savas F, Cavdarli B, Aydin C, Topaloglu O, Ersoy R, Cakir B.   +9 more
europepmc   +1 more source

Non‐linear relationship between liver fibrosis and femoral neck bone mineral density in metabolic dysfunction‐associated fatty liver disease patients with type 2 diabetes mellitus

Journal of Diabetes Investigation, Volume 16, Issue 11, Page 2082-2091, November 2025.
Our study investigates the relationship between hepatic fibrosis and femoral neck bone mineral density (BMD) in MAFLD patients with type 2 diabetes mellitus (T2DM‐MAFLD) and assesses the potential influence of metabolic factors. We found a non‐linear relationship between hepatic fibrosis and femoral neck BMD, particularly evident in postmenopausal ...
Jie Tao, Lin Wang, Honggang Wang, Juan Tan   +3 more
wiley   +1 more source

Extracellular ATP increases agonist potency and reduces latency at class B G protein-coupled receptors. [PDF]

Mol Pharmacol
Zhu S, Yuan A, Duffy T, Kim BH, Ozawa T, Dixon SJ, Chidiac P.   +6 more
europepmc   +1 more source

Neuroendocrinology meets addiction: Emerging pharmacotherapies on the horizon

Journal of Internal Medicine, Volume 298, Issue 5, Page 392-423, November 2025.
Abstract Alcohol and other substance use disorders (ASUDs) are prevalent and major contributors to global morbidity and mortality. Their impact extends beyond the individual, imposing significant burdens on families, communities, healthcare systems, and society at large.
Anna Loften, Mehdi Farokhnia, Leandro F. Vendruscolo, Lorenzo Leggio   +3 more
wiley   +1 more source