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Characterisation of the calcitonin gene-related peptide receptor antagonists ubrogepant and atogepant in human isolated coronary, cerebral and middle meningeal arteries

Cephalalgia, 2020
Background Migraine has been associated with a dysfunctional activation of the trigeminovascular system. Calcitonin gene-related peptide, a neuropeptide released from the trigeminal nerve fibres, has an important role in the pathophysiology of migraine ...
Eloísa Rubio-Beltrán   +4 more
semanticscholar   +1 more source

Calcitonin

Rheumatic Disease Clinics of North America, 1997
Calcitonin is FDA approved for the treatment of postmenopausal osteoporosis but not for prevention. The preferred delivery system is nasal. Nasal calcitonin is safe and well tolerated. The vertebral fracture efficacy of calcitonin is less robust than the two approved bisphosphonates (alendronate and risedronate) but is similar to raloxifene in the ...
openaire   +7 more sources

Calcitonin

Der Schmerz, 1990
A central antinociceptive effect of calcitonin has been well established in animal experiments. Owing to the lack of appropriate studies, however, a final judgement cannot be made regarding the value of calcitonin in pain therapy. Positive clinical experiences have been reported in the following cases.
openaire   +2 more sources

Calcitonin

2003
Mini Review ; There is yet much to learn about the actions and role of CT. It will be important to better understand die physicochemistry of CT-CTR interaction, and the pharmacokinetics of CT, so that small molecule CT-mimetics and more potent, differently delivered, longer acting forms of the molecule can be designed to control bone resorption and ...
Findlay, D., Sexton, P.
openaire   +3 more sources

Calcitonin gene-related peptide levels in tear fluid are elevated in migraine patients compared to healthy controls

Cephalalgia, 2019
Background Calcitonin gene-related peptide (CGRP) released from trigeminal nerve fibres indicates trigeminal activation and has a key role in migraine pathophysiology. The trigeminal nerve directly innervates the eye.
K. Kamm, A. Straube, R. Ruscheweyh
semanticscholar   +1 more source

Calcitonin and Migraine

Headache: The Journal of Head and Face Pain, 1986
SYNOPSIS A group of 30 patients (12 M ‐ 18 F) suffering from migraine underwent salmon calcitonin therapy for a period of one month. All patients were treated at first for 30 days with vehicle administration in a daily i.m. injection, as a control.
PATTI, Francesco   +5 more
openaire   +4 more sources

Nasal calcitonin

Endocrine, 1997
Nasal calcitonin is a newly approved treatment for established osteoporosis that increases lumbar spine bone mass, is safe, and well tolerated. Fracture efficacy data is not yet available, although preliminary results are promising. The dose for established osteoporosis is 200 IU.
openaire   +2 more sources

Empfehlung zum Calcitonin-Screening bei Struma nodosa

Deutsche Medizinische Wochenschrift, 2018
Was ist neu? Calcitonin-Bestimmung Die neuen vollautomatischen Chemilumineszenz-Immunoassays erlauben eine sichere Festlegung geschlechtsspezifischer oberer Referenzwerte für Calcitonin.
K. Frank‐Raue, M. Schott, F. Raue
semanticscholar   +1 more source

Salmon Calcitonin

Orthopaedic Nursing, 1993
Calcitonin has a specific role in prevention and treatment of osteoporotic fractures. Calcitonin is a hormone that is synthesized and secreted by the thyroid gland. The circulating level of ionized calcium controls calcitonin release. Treatment of osteoporosis with calcitonin was approved by the FDA in 1985 (Fatourechi & Health, 1987).
openaire   +2 more sources

Calcitonin and calcitonin receptors.

Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases, 2012
Calcitonin (CT) is a polypeptide hormone with 32 aminoacids syntetized primarily by the thyroid.Several evidences support the existence of nonthyroidal CT like peptide. The CT gene transcript also encodes a distinct peptide known as calcitonin gene related peptide (CGRP) which is a potent vasodilator and responsible for the stimulation of the ...
Masi, Laura, Brandi, Maria Luisa
openaire   +1 more source

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