Results 51 to 60 of about 363,038 (313)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Dietary calcium intake and food sources among Chinese adults in CNTCS. [PDF]

PLoS ONE, 2018
BACKGROUND:Calcium is one of the essential micronutrients in the human body and is well-known for its important role in keeping bones and teeth healthy. However, calcium deficiency is a very common nutritional problem in the world and especially in China.
Feifei Huang, Zhihong Wang, Jiguo Zhang, Wenwen Du, Chang Su, Hongru Jiang, Xiaofang Jia, Yifei Ouyang, Yun Wang, Li Li, Bing Zhang, Huijun Wang   +11 more
doaj   +1 more source

Dietary calcium decreases but short-chain fructo-oligosaccharides increase colonic permeability in rats [PDF]

, 2010
An increased intestinal permeability is associated with several diseases. Nutrition can influence gut permeability. Previously, we showed that dietary Ca decreases whereas dietary short-chain fructo-oligosaccharides (scFOS) increase intestinal ...
Bovee-Oudenhoven, I.M.J., Brummer, R.J.M., Meer, R., van de, Rijnierse, A., Schepens, M.A.A., Schonewille, A.J., Vink, C., Willemsen, L.E.M.   +7 more
core   +3 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Association of dietary calcium with mortality from all causes, cardiovascular disease and cancer in people with hypertension

The Journal of Clinical Hypertension, 2023
Association between calcium intake and premature mortality in the general population has been well studied, but little is known about the association among specific populations.
Ruilang Lin, Wen Feng, Yating Yang, Jiaqin Xu, Hui Yang, Jingyi Wu, Jiong Li, Guoyou Qin, Yongfu Yu, Jiaohua Chen   +9 more
doaj   +1 more source

Evaluation of a Phosphate Management Protocol to Achieve Optimum Serum Phosphate Levels in Hemodialysis Patients [PDF]

, 2008
Original article can be found at: http://www.sciencedirect.com/science/journal/10512276 Copyright National Kidney Foundation, Inc. DOI: 10.1053/j.jrn.2008.05.003To evaluate the effectiveness of a protocol designed to optimize serum phosphate levels in ...
Cheung, C.F., Cunningham, J., Fan, S., Glass, G., Madden, A.M., Yokum, D.   +5 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Association of dietary calcium intake at dinner versus breakfast with cardiovascular disease in U.S. adults: the national health and nutrition examination survey, 2003–2018

BMC Public Health
Background Currently, it is still largely unknown whether the proportion of calcium intake at breakfast and dinner is associated with cardiovascular disease (CVD) in the general population. Objectives The aim of this study was to evaluate the association
Ting Zhang, Sijia Zhuang, Yue Yu, Zizhuo Fan, Xiyun Ren   +4 more
doaj   +1 more source

Exploring the Role of Dietary Calcium Intake in Muscle and Cardiovascular Performance Among Young Athletes

Sports
The importance of dietary calcium intake in bone metabolism has been well established; however, it is still less investigated in health-related components, especially addressing muscle performance.
Pragya Sharma Ghimire, Xiyan Ding, Adam Eckart   +2 more
doaj   +1 more source

Fast-food offerings in the United States in 1986, 1991, and 2016 show large increases in food variety, portion size, dietary energy, and selected micronutrients [PDF]

, 2019
BACKGROUND US national survey data shows fast food accounted for 11% of daily caloric intake in 2007-2010. OBJECTIVE To provide a detailed assessment of changes over time in fast-food menu offerings over 30 years, including food variety (number ...
Appeadu, Sarah, Harbaugh, Allen G., McCrory, Megan A., Roberts, Susan B.   +3 more
core   +1 more source