Results 81 to 90 of about 363,038 (313)

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Dairy consumption and other dietary risk factors for osteoporosis in Croatian young women

Mljekarstvo, 2008
Among dietary risk factors for developing osteoporosis, calcium intake in the primary prevention of osteoporosis has received much attention. The aim of this study was to determine dietary risk factors for later osteoporosis in Croatian young women (mean
Zvonimir Šatalić, Irena Colić Barić, Irena Keser   +2 more
doaj  

Association between dietary calcium intake and constipation in a metabolic syndrome population: evidence from NHANES 2005–2010

Frontiers in Nutrition
BackgroundThe global prevalence of Metabolic Syndrome (MetS) is increasing, primarily characterized by abdominal obesity, which significantly heightens the risk of cardiovascular diseases, gastrointestinal disorders, and cancers. Constipation is a common
Li Zhu, Long Yang, Zonghua Liang, Wen Shi, Ming Ma, Jingbo Chen, Zulipikaer Abdula, Xuchen Gong   +7 more
doaj   +1 more source

The Role of Calcium in Osteoporosis [PDF]

Calcium requirements may vary throughout the lifespan. During the growth years and up to age 25 to 30, it is important to maximize dietary intake of calcium to maintain positive calcium balance and achieve peak bone mass, thereby possibly decreasing the ...
Arnaud, C. D., Sanchez, S. D.
core   +1 more source

Freeze-Dried Ham Promotes Azoxymethane-Induced Mucin-Depleted Foci and Aberrant Crypt Foci in Rat Colon [PDF]

, 2010
Processed and red meat consumption is associated with the risk of colorectal cancer. Meta-analyses have suggested that the risk associated with processed meat is higher. Most processed meats are cured and cooked, which leads to formation of free nitrosyl
Bonneson C, Caderni G, Cross A J, Cummings J H, Denis E. Corpet, Fabrice H. F. Pierre, Françoise Guéraud, Karkare M R, Nathalie Naud, Ossama Allam, Pierre F, Raphaëlle L. Santarelli, Sandhu M S, Sesink A LA, Sinha R, Sylviane Taché, Van Den Berg J W   +16 more
core   +4 more sources

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Comparison of dietary and supplemental calcium - a systematic review

Quality in Sport
Calcium is an essential mineral crucial for several physiological processes. The public has generally perceived its supplementation as beneficial or, at the least, neutral.
Karolina Siembab, Wiktor Garbarczyk, Agnieszka Napieralska, Albert Kapla, Alicja Černohorská, Daria Bednarczyk, Julia Białeta, Katarzyna Rowińska, Michalina Jurkiewicz, Wiktoria Pysiewicz   +9 more
doaj   +1 more source

Dietary Calcium Intake May Contribute to the HOMA-IR Score in Korean Females with Vitamin D Deficiency (2008–2012 Korea National Health and Nutrition Examination Survey)

Journal of Obesity & Metabolic Syndrome, 2017
Background : Vitamin D and calcium are important factors involved in the regulation of blood glucose and insulin secretion. The Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) score is a useful variable for evaluating insulin resistance, and
Jin-Ho Kim, Seok-Hoon Lee, Soo-Jung Park, Kyung-Jin Yeum, Beomhee Choi, Nam-Seok Joo   +5 more
doaj   +1 more source

Dietary Acid Load and Bone Turnover During Long-Duration Spaceflight and Bed Rest [PDF]

Background Bed rest studies document that a lower dietary acid load is associated with lower bone resorption. Objective We tested the effect of dietary acid load on bone metabolism during spaceflight. Design Controlled 4-d diets with a high or low animal
Dlouhy, Holly, Heer, Martina, Koslovsky, Matthew, Rice, Barbara L., Shackelford, Linda C., Smith, Scott M., Zwart, Sara R.   +6 more
core   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source