Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Preparation, characterization and in vitro evaluation of atorvastatin nanosuspensions. [PDF]
Akour YA +4 more
europepmc +1 more source
The Reaction of Aluminum Sulfate and Calcium Carbonate. I. Preparation of Basic Aluminum Sulfate Sol and its Hydrolysis [PDF]
Tsutomu Kuwata, Tadahisa Nakazawa
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Serum Calcium as a Determinant of Fibroblast Growth Factor 23 Levels in Patients With Primary Hyperparathyroidism and Graves' Disease. [PDF]
Yamashita H +9 more
europepmc +1 more source
Ueber die Atomgwichte des Wasserstoffes und des Calciums [PDF]
Otto Linné Erdmann, Robin Marchand
openalex +1 more source
Compounds of the Structural Type of Calcium Titanate [PDF]
H. P. Rooksby
openalex +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Nanoparticle modified paper-based analytical sensor for calcium determination in human nasal secretions and its association with olfactory dysfunction. [PDF]
Imam MS +11 more
europepmc +1 more source

