Results 221 to 230 of about 1,315,620 (268)
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Journal of Molecular and Cellular Cardiology, 1986
In contrast to nifedipine-like calcium antagonists, calcium agonistic 1,4-dihydropyridines have vasoconstricting and positive inotropic properties. BAY K 8644 has become the prototype of this new class. Its enantiomers show opposite effects on the calcium channel: one acts as a calcium agonist with the pharmacological profile of the racemic compound ...
M, Bechem, M, Schramm
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In contrast to nifedipine-like calcium antagonists, calcium agonistic 1,4-dihydropyridines have vasoconstricting and positive inotropic properties. BAY K 8644 has become the prototype of this new class. Its enantiomers show opposite effects on the calcium channel: one acts as a calcium agonist with the pharmacological profile of the racemic compound ...
M, Bechem, M, Schramm
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Atherogenesis, calcium and calcium antagonists
The American Journal of Cardiology, 1990Hypercholesterolemia and arterial hypertension are highly interrelated risk factors of atherosclerosis. Early lesions in nonhuman primates with dietary hypercholesterolemia resemble atherosclerotic lesions demonstrable in the arteries of American children with comparably elevated plasma cholesterol levels.
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The Journal of Nutrition, 1986
It seems we are about back to square one and the question that still needs an answer is whether diet, or calcium intake, plays a really significant role in the etiology of osteoporosis, especially hip fractures. Logic may tell us that calcium intake ought to be important but the evidence is weak.
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It seems we are about back to square one and the question that still needs an answer is whether diet, or calcium intake, plays a really significant role in the etiology of osteoporosis, especially hip fractures. Logic may tell us that calcium intake ought to be important but the evidence is weak.
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Calcium, Calcium Translocation, and Specific Calcium Antagonists
1978It is now almost one hundred years since Sidney Ringer (1882) described the importance of Ca2+ in the maintenance of frog heart contractility. Subsequent to this observation, it has been increasingly recognized that Ca2+ plays a critical and central role in a multitude of biological events at both the intra-and extracellular levels (Duncan, 1976 ...
L. Rosenberger, D. J. Triggle
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2000
The article contains sections titled: 1. Introduction 2. Physical and Chemical Properties 3. Production 4. Uses 5. Occupational Health and Safety 6. Biological Relevance 6.1. Introduction 6.2. Chemical Properties of Ca Important in Biological Functions 6.3. Dietary Considerations; Distribution in the Body 6.4.
Stephen E. Hluchan, Kenneth Pomerantz
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The article contains sections titled: 1. Introduction 2. Physical and Chemical Properties 3. Production 4. Uses 5. Occupational Health and Safety 6. Biological Relevance 6.1. Introduction 6.2. Chemical Properties of Ca Important in Biological Functions 6.3. Dietary Considerations; Distribution in the Body 6.4.
Stephen E. Hluchan, Kenneth Pomerantz
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Calcium-dependent and calcium-independent exocytosis
Trends in Neurosciences, 1989A large body of evidence supports the concept that calcium (Ca2+) plays a pivotal role in the control of exocytosis. However, recent experiments suggest that a rise in intracellular Ca2+ does not necessarily trigger secretion, and also that secretion can occur independently of cytosolic free calcium levels.
D E, Knight +2 more
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Calcium Entry, Calcium Redistribution, and Exocytosis
Annals of the New York Academy of Sciences, 2002Abstract: At a given cytosolic domain of a chromaffin cell, the rate and amplitude of the Ca2+ concentration, [Ca2+]c, depend on at least three efficient regulatory mechanisms: (1) the plasmalemmal Ca2+ channels; (2) the endoplasmic reticulum (ER); and (3) the mitochondria.
Inmaculada, Cuchillo-Ibanez +5 more
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Calcium and calcium-binding proteins in the nucleus
Molecular and Cellular Biochemistry, 1994Calcium has long been known to play a role as a key cytoplasmic second messenger, but until relatively recently its possible involvement in nuclear signal transduction and the regulation of nuclear events has not been extensively studied. Evidence revealing the presence of transmembrane nuclear Ca2+ gradients and a variety of intranuclear Ca2+ binding ...
J S, Gilchrist +2 more
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Calcium-induced calcium release in neurones
Cell Calcium, 1996Neurones express several subtypes of intracellular Ca2+ channels, which are regulated by cytoplasmic calcium concentration ([Ca2+]c) and provide the pathway for Ca(2+)-induced Ca2+ release (CICR) from endoplasmic reticulum Ca2+ stores. The initial studies of CICR which employed several pharmacological tools (and in particular caffeine and ryanodine ...
Verkhratsky, A.; id_orcid 0000-0003-2592-9898 +1 more
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Simulation Strategies for Calcium Microdomains and Calcium-Regulated Calcium Channels
2012In this article, we present an overview of simulation strategies in the context of subcellular domains where calcium-dependent signaling plays an important role. The presentation follows the spatial and temporal scales involved and represented by each algorithm.
Frederic, von Wegner +2 more
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