Calcium-Channel-Blocker-Influenced Gingival Enlargement: A Conundrum Demystified
Oral, 2021 The aim of the article is to discuss the development of calcium channel blocker (CCB) influenced gingival enlargement. Data and Sources: MEDLINE/PubMed, Scopus, ScienceDirect, and Google Search databases.
Pallavi Tonsekar, Vidya Tonsekar
doaj +1 more source
Molecular Oncology, EarlyView.Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka +10 more
wiley +1 more source
Performance of Predictive Indoor mmWave Networks with Dynamic Blockers [PDF]
arXiv, 2021 In this paper, we consider millimeter Wave (mmWave) technology to provide reliable wireless network service within factories where links may experience rapid and temporary fluctuations of the received signal power due to dynamic blockers, such as humans and robots, moving in the environment.
arxiv
Novel Effects of Mibefradil, An Anti-Cancer Drug, on White Adipocytes [PDF]
, 2017 The present study was undertaken to investigate the effects of the T-type calcium channel blocker, Mibefradil, on white adipocytes. Unexpected for a T-type channel blocker, Mibefradil was found to increase intracellular calcium levels, cause lipid ...
Thompson, Sonia
core +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
The EuroHeart Failure Survey programme—a survey on the quality of care among patients with heart failure in Europe Part 2: treatment [PDF]
, 2003 National surveys suggest that treatment of heart failure in daily practice differs from guidelines and is characterized by underuse of recommended medications.
Aguilar, JC +17 more
core +2 more sources
Prescribing Patterns and Cost of Antihypertensive Drugs in Private Hospitals in Dar es Salaam, Tanzania [PDF]
, 2009 Antihypertensive agents are used to prevent morbidity and mortality related to hypertension. Prescribing patterns and the cost of some antihypertensive were studied for 600 patients attending medical clinics in four private hospitals in Dar es Salaam ...
Justin-Temu, M, Nilay, C, Rimoy, GH
core +2 more sources
The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines. [PDF]
, 2000 The pharmacology of hSK1, a small conductance calcium-activated potassium channel, was studied in mammalian cell lines (HEK293 and COS-7). In these cell types, hSK1 forms an apamin-sensitive channel with an IC(50) for apamin of 8 nM in HEK293 cells and ...
BENTON +14 more
core +2 more sources
FM1-43 dye behaves as a permeant blocker of the hair-cell mechanotransducer channel [PDF]
, 2001 Hair cells in mouse cochlear cultures are selectively labeled by brief exposure to FM1-43, a styryl dye used to study endocytosis and exocytosis. Real-time confocal microscopy indicates that dye entry is rapid and via the apical surface.
Gale, J.E. +4 more
core +1 more source
Comparison of First-Line Dual Combination Treatments in Hypertension: Real-World Evidence from Multinational Heterogeneous Cohorts. [PDF]
, 2020 Background and objectives: 2018 ESC/ESH Hypertension guideline recommends 2-drug combination as initial anti-hypertensive therapy. However, real-world evidence for effectiveness of recommended regimens remains limited.
Cho, Jaehyeong +10 more
core