Results 111 to 120 of about 129,457 (298)

Nifedipine promotes the proliferation and migration of breast cancer cells.

PLoS ONE, 2014
Nifedipine is widely used as a calcium channel blocker (CCB) to treat angina and hypertension,but it is controversial with respect the risk of stimulation of cancers. In this study, we demonstrated that nifedipine promoted the proliferation and migration
Dong-Qing Guo, Hao Zhang, Sheng-Jiang Tan, Yu-Chun Gu   +3 more
doaj   +1 more source

Reply to the Letter “Create Guidelines for Characterization of Venom Peptides” from Dr. Volker Herzig

Toxins, 2016
Regarding our paper “PhTx3-4, a Spider Toxin Calcium Channel Blocker, Reduces NMDA-Induced Injury of the Retina”, published in Toxins 2016, 8, doi:10.3390/toxins8030070 [1].[...]
Marcus Vinicius Gomez
doaj   +1 more source

Convulsant actions of 4-aminopyridine on the guinea-pig olfactory cortex slice [PDF]

, 1982
The effects of bath-applied 4-aminopyridine on neurones and extracellular potassium and calcium concentrations were recorded in slices of guinea-pig olfactory cortex. Neurones were orthodromically activated by stimulating the lateral olfactory tract.
Baranyi, Ben-Ari, Brismar, Brown, Buckle, Collins, Constanti, DiFrancesco, Dingemanse, Galvan, Galvan, Galvan, Gerrit Ten Bruggencate, Gilbey, Golenhofen, Halliwell, Heinemann, Jankowska, Jefferys, Kocsis, Lemeignan, Lipicky, Llinaś, Lundh, Martin Galvan, Matthews, McAfee, Mori, Neuman, Nicholson, Nicoll, Pelhate, Peter Grafe, Pichon, Scholfield, Scholfield, Schwartzkroin, Schwartzkroin, Sherratt, Shimahara, Spyker, Szente, Thesleff, Thompson, Ulbricht, von Haxthausen, Yanagisawa, Yeh   +47 more
core   +1 more source

Development and Preliminary In Vivo Study of 3D‐Printed Bioactive Glass Scaffolds with Trabecular Architecture

Advanced Engineering Materials, EarlyView.
This study reports the fabrication of trabecular bioactive glass scaffolds (composition “1d”: 46.1SiO2‐28.7CaO‐8.8MgO‐6.2P2O5‐5.7CaF2‐4.5Na2O wt%) through vat photopolymerization and the relevant results from mechanical testing and in vivo implantation procedures in rabbit femora, showing great promise for bone tissue engineering applications.
Dilshat Tulyaganov, Roberta Gabrieli, Avzal Akbarov, Nigora Nigmatova, Bekhzod Khabilov, Alessandro Schiavi, Martin Schwentenwein, Enrica Verné, Francesco Baino   +8 more
wiley   +1 more source

Trace Nickel Activated Biphasic Core‐CuOii/Shell‐CuOi Secondary Microspheres Enable Room Temperature Parts‐Per‐Trillion‐Level NO2 Detection

Advanced Engineering Materials, EarlyView.
An idea of designing novel sensors is proposed by creating appropriate Schottky barriers and vacancies between isomorphous Core‐CuOii/ Shell‐CuOi secondary microspheres and enhancing catalytic and spill‐over effects, and electronegativity via spontaneous biphasic separation, self‐assembly, and trace‐Ni‐doping.
Bala Ismail Adamu, Peipei Chen, Shafia Mukhtar Ibrahim, Mukhtar Lawan Adam, Attia Falak, Mokhotjwa Simon Dhlamini, Hanfu Wang, Lingxiang Jiang, Weiguo Chu   +8 more
wiley   +1 more source

K-ATP channel gene expression is induced by urocortin and mediates its cardioprotective effect [PDF]

, 2002
Background-Urocortin is a novel cardioprotective agent that can protect cardiac myocytes from the damaging effects of ischemia/reperfusion both in culture and in the intact heart and is effective when given at reperfusion.Methods and Results-We have ...
Chanalaris, A, Comini, L, Ferrari, R, Hubank, M, Knight, RA, Latchman, DS, Lawrence, KM, Pasini, E, Scarabelli, T, Stephanou, A, Tinker, A, Townsend, PA   +11 more
core  

What Do Large Language Models Know About Materials?

Advanced Engineering Materials, EarlyView.
If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer, Thomas Wallmersperger, Gianaurelio Cuniberti   +2 more
wiley   +1 more source

Advancing Electronic Application of Coordination Solids: Enhancing Electron Transport and Device Integration via Surface‐Mounted MOFs (SURMOFs)

Advanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of coordination solids, enabled by the surface‐mounted metal‐organic framework (SURMOF) platform, is on the cusp of generating the organic counterpart of the epitaxy of inorganics. The programmable and sequential SURMOF protocol, optimized by machine learning (ML), is suited for accessing high‐quality thin films of ...
Zhengtao Xu, Christof Wöll, Stefan Bräse   +2 more
wiley   +1 more source

Ventricular Action Potential Adaptation to Regular Exercise: Role of β-adrenergic and K\u3csub\u3eATP\u3c/sub\u3e Channel Function [PDF]

, 2017
Regular exercise training is known to affect the action potential duration (APD) and improve heart function, but involvement of β-adrenergic receptor (β-AR) subtypes and/or the ATP-sensitive K+ (KATP) channel is unknown.
Fitts, Robert H., Wang, Xinrui
core   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source