Results 141 to 150 of about 212,769 (372)

Lipid-mediated hydrophobic gating in the BK potassium channel [PDF]

open access: yesarXiv
The large-conductance, calcium-activated potassium (BK) channel lacks the typical intracellular bundle-crossing gate present in most ion channels of the 6TM family. This observation, initially inferred from Ca$^{2+}$-free-pore accessibility experiments and recently corroborated by a CryoEM structure of the non-conductive state, raises a puzzling ...
arxiv  

Identifikasi Senyawa Fitokimia Calcium Channel Blocker dengan Molecular Docking sebagai Pengembangan Terapi Hipertensi pada Kehamilan [PDF]

open access: yes, 2017
Asma Azizah, G0013043, 2017. Identification of Phytochemical as Calcium Channel Blocker by Molecular Docking for Treatment of Hypertension in Pregnancy. Mini Thesis. Faculty of Medicine, Universitas Sebelas Maret, Surakarta. Introduction: Hypertension in
AZIZAH, ASMA
core  

Epitope Mapping of Anti‐Neurofascin 155 Antibody in a Large Cohort of Autoimmune Nodopathy Patients

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune nodopathy (AN), a newly recognized disease entity, is an immune‐mediated polyneuropathy involving autoantibodies against cell adhesion molecules located in nodes of Ranvier and paranodal regions, such as neurofascin 186 (NF186) and neurofascin 155 (NF155). The present study aimed to identify the epitopes for autoantibodies
Amina A. Abdelhadi   +6 more
wiley   +1 more source

A Modern View on the Treatment for Acute Calcium Channel Blocker Poisoning

open access: yesНеотложная медицинская помощь
BACKGROUND. At the beginning of the 21st century, the structure of acute exotoxicoses changed, in particular, an increase in poisoning by drugs that mainly affect the cardiovascular system, including calcium channel blockers, was noted.
A. Yu. Simonova   +4 more
doaj   +1 more source

Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis

open access: yesAdvanced Biology, EarlyView.
Transmembrane signaling is the hallmark of living cells and is among the highest challenges for the design of synthetic cells. Herein, an artificial receptor based on the chemistry of self‐immolative linkers is used to communicate information across the lipid bilayer, for transmembrane activation of enzymatic activity. Abstract The design of artificial,
Ane Bretschneider Søgaard   +7 more
wiley   +1 more source

Efficacy and mechanism of action of a calcium channel blocker after global cerebral ischemia in rats. [PDF]

open access: bronze, 1988
James C. Grotta   +5 more
openalex   +1 more source

Blockade of current through single calcium channels by trivalent lanthanide cations. Effect of ionic radius on the rates of ion entry and exit. [PDF]

open access: yes, 1990
Currents flowing through single dihydropyridine-sensitive Ca2+ channels were recorded from cell-attached patches on C2 myotubes. In the presence of dihydropyridine agonist to prolong the duration of single-channel openings, adding micromolar ...
Lansman, JB
core  

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