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Differentiation of Calcium Entry Blockers into Calcium Channel Blockers and Calcium Overload Blockers

European Neurology, 2008
The heterogeneity of the several subgroups of calcium-antagonistic drugs requires a rigid and well-defined differentiation of this type of agents. From the chemical point of view verapamil-like drugs, dihydrophyridines, benzothiazepines and diphenylalkylamines should be distinguished. Among these largely different groups no obvious relationship between
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Calcium Channel Blocker Toxicity

Pediatric Emergency Care, 2009
Calcium channel blockers continue to be used for the management of a wide variety of adult and pediatric conditions including hypertension, angina pectoris, atrial arrhythmias, Raynaud phenomenon, and migraine headaches. With increased use comes increased potential for misuse and abuse.
Anna Maria, Arroyo, Louise W, Kao
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Chromatography of calcium channel blockers

Journal of Chromatography B: Biomedical Sciences and Applications, 1990
Numerous publications during the past ten years have described the determination of various calcium channel blockers in biological fluids, using gas and liquid chromatographic techniques. Diltiazem, verapamil, flunarizine and a growing number of dihydropyridines belong to this group of drugs, which in most instances are active at low plasma ...
M, Ahnoff, B A, Persson
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Calcium channel blockers in psychiatry

1996
The influence of calcium in mental disorders has been considered over time. For example, intravenous calcium gluconate was used for treatment of periodic psychosis as late as the 1970s. Also, mental symptoms may be prominent in patients with hypercalcemia of various causes.
L E, Hollister, E S, Garza-Trevino
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Calcium channel blockers in psychiatry

Psychosomatics, 1987
Abstract Calcium channel blockers have an established role in the treatment of various cardiovascular disorders and potential applications in psychiatry. Preliminary reports based on limited numbers of patients indicate that they are promising for mania, of uncertain utility for depression or schizophrenia, and deserving of further investigation for ...
M H, Pollack, J F, Rosenbaum, S E, Hyman
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Calcium channel blocker toxicity

Annals of Emergency Medicine, 1990
A retrospective review was conducted of all patients who were reported to a regional poison control center after "overdose" of a calcium channel blocker during a two-year period (1987 and 1988). An analysis of 91 patient cases is presented after excluding allergic reactions, cases involving coingestants, and patients lost to follow-up.
E A, Ramoska, H A, Spiller, A, Myers
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Calcium channel blockers and atherogenesis

The American Journal of Medicine, 1987
The events involved in atherogenesis include platelet deposition on damaged endothelial surfaces; migration and proliferation of smooth muscle cells; the formation of elastin, collagen, and glycosaminoglycans, followed by the penetration and complexing of lipoproteins; and, calcification.
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Calcium channel blockers and asthma

Lung, 1986
An increase in cytoplasmic Ca++ concentration can activate not only respiratory smooth muscles, but also mast cells, bronchial mucus glands, and the vagi. Altered control of cytoplasmic Ca++ may also be related to the development of bronchial hyperreactivity.
So, SY, Ip, M, Lam, WK
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Review of Calcium-Channel Blockers

The Nurse Practitioner, 1986
Calcium-channel blocking drugs were introduced to the United States in 1982. The three approved calcium-channel blockers--nifedipine, verapamil and diltiazem--have offered new treatments for angina. This article presents an overview of these drugs with emphasis on their mechanisms of action, clinical use and guidelines for the nurse practitioner in ...
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Calcium channel blockers as tocolytics

Seminars in Perinatology, 2001
This article reviews the clinical and basic science investigations regarding the safety and efficacy of calcium channel blockers as tocolytic agents. The authors reviewed the English language literature on the pharmacology and clinical applications of calcium antagonists in obstetrics.
K E, Economy, A Z, Abuhamad
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