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Review of Calcium-Channel Blockers
The Nurse Practitioner, 1986Calcium-channel blocking drugs were introduced to the United States in 1982. The three approved calcium-channel blockers--nifedipine, verapamil and diltiazem--have offered new treatments for angina. This article presents an overview of these drugs with emphasis on their mechanisms of action, clinical use and guidelines for the nurse practitioner in ...
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Calcium Channel Blockers and Atherosclerosis
Journal of Cardiovascular Pharmacology, 1990There is evidence that calcium antagonists (calcium channel blockers) may suppress atheroma formation in animals fed high-fat diets. Studies on the antiatherosclerotic effects of calcium blockers have suggested a variety of possible mechanisms: (a) lowering of arterial pressure, (b) decrease in atherogenic plasma lipoproteins, (c) suppression of ...
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Calcium channel blockers and stroke.
Aging clinical and experimental research, 2005The most frequent indication for Calcium Channel Blockers (CCBs) is their use as antihypertensive agents for primary or secondary stroke prevention. Hypertension contributes to virtually all mechanisms of stroke, of atherothrombotic, lacunar, cardioembolic and intraparenchymal hemorrhage types.
INZITARI, DOMENICO, POGGESI, ANNA
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Calcium channel blockers and the kidney
Clinical Cornerstone, 2004Although end-stage renal disease (ESRD) currently affects only a small percentage (
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Calcium channel blockers in psychiatry
1996The influence of calcium in mental disorders has been considered over time. For example, intravenous calcium gluconate was used for treatment of periodic psychosis as late as the 1970s. Also, mental symptoms may be prominent in patients with hypercalcemia of various causes.
L E, Hollister, E S, Garza-Trevino
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Calcium Channel Blockers in Systemic Hypertension
Medical Clinics of North America, 1987Alterations in transmembrane flux of calcium ions may be playing a role in the pathophysiology of systemic hypertension. Calcium channel blockers have been shown to be effective antihypertensive drugs with excellent safety profiles. They are efficacious in the long term treatment of systemic hypertension in all population subgroups, and have special ...
W H, Frishman +5 more
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Calcium Channel Blockers and Essential Tremor
European Neurology, 2008Acute effects of two calcium blockers, nifedipine and verapamil, were investigated on the tremor activity of 8 patients with essential tremor and compared with those of propranolol and placebo. Following a single oral dose of 10 mg of nifedipine, tremor intensity of the patients was increased by 71.4 ± 22.6%.
TOPAKTAS, S, ONUR, R, DALKARA, T
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On the specificity of verapamil as a calcium channel-blocker
Biochemical Pharmacology, 1985The stimulated uptake of 45Ca2+ into incubated cerebrocortical synaptosomes caused by veratrine (75 microM) was blocked by low concentrations of verapamil (0.5-30 microM) which did not prevent or reduce depolarization as judged by efflux of potassium (K+).
D K, Norris, H F, Bradford
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Postgraduate Medicine, 1997
Although the calcium channel blockers have been used to treat hypertension for a number of years, they are now under close scrutiny because of disturbing findings regarding their safety. Drs Kochar and Qurashi sort out the controversies surrounding these widely used drugs and make recommendations based on current consensus.
M S, Kochar, M I, Qurashi
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Although the calcium channel blockers have been used to treat hypertension for a number of years, they are now under close scrutiny because of disturbing findings regarding their safety. Drs Kochar and Qurashi sort out the controversies surrounding these widely used drugs and make recommendations based on current consensus.
M S, Kochar, M I, Qurashi
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