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Reactions, 1985
Verapamil may have application in the field of obstetrics for treatment of maternal and fetal tachyarrhythmias. This study was performed to assess the maternal and fetal hemodynamic effects of this drug, as well as to determine its placental transfer and effects on maternal and fetal atrioventricular conduction in the pregnant ewe. Verapamil, 0.2 mg/kg,
S. H. N. Murad +6 more
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Verapamil may have application in the field of obstetrics for treatment of maternal and fetal tachyarrhythmias. This study was performed to assess the maternal and fetal hemodynamic effects of this drug, as well as to determine its placental transfer and effects on maternal and fetal atrioventricular conduction in the pregnant ewe. Verapamil, 0.2 mg/kg,
S. H. N. Murad +6 more
openaire +2 more sources
On the conversion of verapamil to carboxy verapamil.
Research communications in chemical pathology and pharmacology, 1986The reaction of verapamil with concentrated sulfuric acid was studied. It was found, in disagreement with a published report, that the reaction did not hydrolyze the nitrile group of the drug to the corresponding carboxylic acid, but, instead, produced a sulfonated derivative.
J, Gal +4 more
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