Results 11 to 20 of about 46,600 (231)

Verapamil Induces Calcium Influx in the Trachea

open access: yesJournal of Pharmacological Sciences, 2008
Verapamil, a Ca2+entry blocker, can induce bronchorelaxation and bronchoconstriction. The mechanism of verapamil-induced bronchoconstriction is poorly understood.
Seham Mustafa   +2 more
doaj   +2 more sources

Pharmacokinetic Interaction between Metformin and Verapamil in Rats: Inhibition of the OCT2-Mediated Renal Excretion of Metformin by Verapamil

open access: yesPharmaceutics, 2020
The incidence of hypertension in diabetic patients has been increasing and contributing to the high mortality of diabetic patients. Recently, verapamil use was found to lower fasting blood glucose levels in diabetic patients, which led to a new ...
Seung Yon Han, Young Hee Choi
doaj   +2 more sources

Verapamil HCl demonstrates antiviral activity against porcine reproductive and respiratory syndrome virus by regulating Ca2+ influx and promoting type I interferon production [PDF]

open access: yesMicrobiology Spectrum
Porcine reproductive and respiratory syndrome virus (PRRSV) poses a major challenge to swine health, impairing reproductive performance and causing respiratory disorders in pigs.
Tongtong Wang   +12 more
doaj   +2 more sources

Genetic variants related to successful migraine prophylaxis with verapamil

open access: yesMolecular Genetics & Genomic Medicine, 2021
Background Currently, there is no biologically based rationale for drug selection in migraine prophylactic treatment. Methods To investigate the genetic variation underlying treatment response to verapamil prophylaxis, we selected 225 patients from a ...
Fred Michael Cutrer   +10 more
doaj   +2 more sources

Verapamil Inhibits Aspergillus Biofilm, but Antagonizes Voriconazole

open access: yesJournal of Fungi, 2017
The paucity of effective antifungals against Aspergillus and increasing resistance, the recognition of the importance of Aspergillus biofilm in several clinical settings, and reports of verapamil—a calcium channel blocker—efficacy against Candida biofilm
Hasan Nazik   +2 more
doaj   +2 more sources

PROTECTIVE EFFECTS OF VERAPAMIL AGAINST HEXACHLOROBUTADIENE NEPHROTOXICITY IN RATS [PDF]

open access: yesPakistan Veterinary Journal, 2008
In order to evaluate the protective effect of verapamil against hexachlorobutadiene (HCBD) nephrotoxicity, 30 adult Wistar albino rats were divided into five equal groups, A, B, C, D and E and were given intra-peritonially corn oil (I ml/kg; control ...
E. MOGHTADAI KHORASGANI, K. MANOCHEHRI AND M. HOSSEINI1
doaj   +2 more sources

Applications of human microdosing with accelerator mass spectrometry: assessment of ability to predict drug-drug interactions and determine the pharmacokinetics of enantiomers [PDF]

open access: yes, 2012
In this thesis, new applications of microdosing were explored in two clinical trials. Methods were developed for the separation and quantification of 14C-labelled analytes in human plasma using two-dimensional HPLC and accelerator mass ...
Croft, M L
core   +6 more sources

Verapamil Potentiometric Membrane Sensor for Verapamil Pharmaceutical Analysis. Computational Investigation

open access: yesInternational Journal of Electrochemical Science, 2009
Verapamil is a calcium channel blocker used in the management of angina, arrhythmia and hypertension. In this study a potentiometric liquid membrane sensor is used for simple and fast determination of verapamil in pharmaceutical formulation and urine ...
F Faridbod, S Riahi, P Norouzi
exaly   +3 more sources

Evaluating the antidiabetic effects of R-verapamil in type 1 and type 2 diabetes mellitus mouse models

open access: yesPLoS ONE, 2021
The global incidence of diabetes mellitus (DM) is increasing. Types 1 and 2 DM are associated with declining β-cell function. Verapamil (50% S-verapamil and 50% R-verapamil) can treat DM by downregulating thioredoxin-interacting protein (TXNIP), which ...
Yu-Syuan Chen   +8 more
doaj   +2 more sources

Solanaceae glycoalkaloids: α-solanine and α-chaconine modify the cardioinhibitory activity of verapamil

open access: yesPharmaceutical Biology, 2022
Context Solanaceae glycoalkaloids (SGAs) possess cardiomodulatory activity.Objective This study investigated the potential interaction between verapamil and glycoalkaloids.Material and methods The cardioactivity of verapamil and glycoalkaloids (α ...
Szymon Chowański   +9 more
doaj   +1 more source

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