Results 21 to 30 of about 68,523 (237)

Assessment of extracts from red yeast rice for herb-drug interaction by in-vitro and in-vivo assays [PDF]

, 2012
Red yeast rice (RYR) is made by fermenting the yeast Monascus purpureus over rice. It is a source of natural red food colorants, a food garnish and a traditional medication.
Fung, W.T., Subramaniam, G., Lee, J., Loh, H.M., Leung, P.H.H.   +4 more
core   +2 more sources

Mechanism Underlying the Reversal of Drug Resistance in P-Glycoprotein-Expressing Leukemia Cells by Pinoresinol and the Study of a Derivative [PDF]

, 2017
P-glycoprotein (P-gp) is a membrane protein associated with multidrug resistance (MDR) due to its key role in mediating the traffic of chemotherapeutic drugs outside cancer cells, leading to a cellular response that hinders efforts toward successful ...
Carpinella, Maria Cecilia, Gancedo, Samanta, González, María Laura, Joray, Mariana Belén, Laiolo, Jerónimo, Lanza Castronuovo, Priscila Ailin, Maccioni, Mariana, Molina, Gabriela, Palacios, Sara Maria, Rumjanek, Vivian, Vera, Domingo Mariano Adolfo   +10 more
core   +2 more sources

Verapamil Induces Calcium Influx in the Trachea

Journal of Pharmacological Sciences, 2008
Verapamil, a Ca2+entry blocker, can induce bronchorelaxation and bronchoconstriction. The mechanism of verapamil-induced bronchoconstriction is poorly understood.
Seham Mustafa, Abdulkareem Abdulraheem, Abdulhakeem Alsughayer   +2 more
doaj   +1 more source

Pharmacokinetic Interaction between Metformin and Verapamil in Rats: Inhibition of the OCT2-Mediated Renal Excretion of Metformin by Verapamil

Pharmaceutics, 2020
The incidence of hypertension in diabetic patients has been increasing and contributing to the high mortality of diabetic patients. Recently, verapamil use was found to lower fasting blood glucose levels in diabetic patients, which led to a new ...
Seung Yon Han, Young Hee Choi
doaj   +1 more source

Kinetic Aspects of Verapamil Binding (On-Rate) on Wild-Type and Six hKv1.3 Mutant Channels

Cellular Physiology and Biochemistry, 2017
Background/Aims: The human-voltage gated Kv1.3 channel (hKv1.3) is expressed in T- and B lymphocytes. Verapamil is able to block hKv1.3 channels. We characterized the effect of verapamil on currents through hKv1.3 channels paying special attention to the
Ann-Kathrin Diesch, Stephan Grissmer
doaj   +1 more source

COMPARISON OF APOPTOSIS IN CONTRALATERAL RENAL TUBULAR CELLS IN ORYCTALAGUS CUNICULUS DUE TO ARTIFICIAL UNILATERAL URETERAL OBSTRUCTION, WITH AND WITHOUT VERAPAMIL

Jurnal Urologi Indonesia, 2016
Objective: To compare the effects of verapamil on the contralateral kidney affected by unilateral ureter obstruction. Material & method: The right ureter of oryctalagus cuniculus rabbits, were obstructed surgically with silk suture material, and kept ...
Djoyo M Boetoro, Soetojo Soetojo, Doddy M Soebadi, Endang Joewarini, Widodo J P   +4 more
doaj   +1 more source

Reasoning by analogy in the generation of domain acceptable ontology refinements [PDF]

, 2010
Refinements generated for a knowledge base often involve the learning of new knowledge to be added to or replace existing parts of a knowledge base. However, the justifiability of the refinement in the context of the domain (domain acceptability) is ...
L. Moss, L. Zhou, M. Horridge, M. Ricklefs, N. Noy, Y. Sure   +5 more
core   +1 more source

Influence of Water Temperature on the MXR Activity and P-glycoprotein Expression in the Freshwater Snail, Physa acuta (Draparnaud, 1805) [PDF]

, 2017
P-glycoprotein (P-gp) mediated multixenobioticresistance (MXR) is a mechanism analogous to multidrug resistance, which has been extensivelycharacterized in mammalian tumours.
Assef, Yanina Andrea, Horak, Cristina Natalia   +1 more
core   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

The protective effect of bee venom against verapamil embryotoxicity during prenatal liver and kidney development of mice Mus musculus

Journal of Basic and Applied Zoology, 2016
Verapamil is a calcium channel blocker that has been widely used in the treatment of cardiovascular abnormalities, hypertension and angina pectoris. The present study investigates the effect of bee venom against verapamil embryotoxicity, bee venom (BV ...
Amin A. Seleem
doaj   +1 more source