Regulation of bicarbonate secretion in marine fish intestine by the calcium-sensing receptor [PDF]
In marine fish, high epithelial intestinal HCO3- secretion generates luminal carbonate precipitates of divalent cations that play a key role in water and ion homeostasis.
Fuentes, Juan, Gregorio, Silvia
core +6 more sources
In vitro analysis of urinary stone composition in dual-energy computed tomography [PDF]
Purpose: Dual energy computed tomography (DECT) is a new method of computed tomography (CT) imaging, allowing the assessment of not only the object's morphology, but also its composition.
Chrzan, Robert+2 more
core +1 more source
Small-molecule CaVα1⋅CaVβ antagonist suppresses neuronal voltage-gated calcium-channel trafficking [PDF]
Extracellular calcium flow through neuronal voltage-gated CaV2.2 calcium channels converts action potential-encoded information to the release of pronociceptive neurotransmitters in the dorsal horn of the spinal cord, culminating in excitation of the ...
Chen, Xingjuan+10 more
core +1 more source
X-ray diffraction study of cadmium hydroxyapatite [PDF]
Solid solutions of cadmium and calcium hydroxyapatite [Ca10−x Cdx (PO4)6 (OH)2 (0 ≤ x ≤ 10)] were synthesized by a wet process in a basic medium. The lattice dimensions of these compounds vary linearly with the atom percent cadmium.
Ait Ichou, Yhya+4 more
core +2 more sources
Targeting cellular calcium homeostasis to prevent cytokine-mediated beta cell death [PDF]
Pro-inflammatory cytokines are important mediators of islet inflammation, leading to beta cell death in type 1 diabetes. Although alterations in both endoplasmic reticulum (ER) and cytosolic free calcium levels are known to play a role in cytokine ...
Abreu, Damien+9 more
core +2 more sources
FSA Neutralization with Calcium Compounds
AbstractAs environmental regulations continue to restrict chemical processing emissions, phosphate plant operators will eventually be required to neutralize fluoride waste materials. Most phosphate plants currently use direct contact barometric condensers with recirculating cooling pond water that is saturated with fluoride salts. Most of this fluoride
Salah F. Albustami, Stephen W. Hilakosa
openaire +2 more sources
Canvass: A crowd-sourced, natural-product screening library for exploring biological space [PDF]
NCATS thanks Dingyin Tao for assistance with compound characterization. This research was supported by the Intramural Research Program of the National Center for Advancing Translational Sciences, National Institutes of Health (NIH). R.B.A.
Majumdar, Susruta
core +4 more sources
Regulation of intracellular cyclic GMP concentration by light and calcium in electropermeabilized rod photoreceptors. [PDF]
This study examines the regulation of cGMP by illumination and by calcium during signal transduction in vertebrate retinal photoreceptor cells. We employed an electropermeabilized rod outer segment (EP-ROS) preparation which permits perfusion of low ...
Coccia, V J, Cote, Rick H.
core +2 more sources
The sleep-inducing lipid oleamide deconvolutes gap junction communication and calcium wave transmission in glial cells. [PDF]
Oleamide is a sleep-inducing lipid originally isolated from the cerebrospinal fluid of sleep-deprived cats. Oleamide was found to potently and selectively inactivate gap junction-mediated communication between rat glial cells.
Cao+35 more
core +2 more sources
RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca2+ assays. [PDF]
Elevated cytoplasmic [Ca2+] is characteristic in severe skeletal and cardiac myopathies, diabetes, and neurodegeneration, and partly results from increased Ca2+ leak from sarcoplasmic reticulum stores via dysregulated ryanodine receptor (RyR) channels ...
Bers, Donald M+6 more
core +2 more sources